The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials
Abstract
Background The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults.Methods Randomized controlled trials that examined the effects of walking on total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), the ratio of TC/HDL, and triglycerides (TG) in adults ages 18 years and older were retrieved via computerized literature searches, cross-referencing, hand-searching, and expert review of our reference list.Results Twenty-five studies that included 1,176 subjects (692 walkers, 484 controls) and up to 33 outcomes were available for pooling. Using random-effects modeling, statistically significant, walking-induced decreases of 5% and 6% were observed for LDL-C and TC/HDL-C (LDL-C, mean +/- SE, -5.5 +/- 2.2 mg/dL, 95% CI, -9.9 to -1.2 mg/dL; TC/HDL-C, mean +/- SE, -0.3 +/- 0.1, 95% CI, -0.6 to -0.1). No statistically significant changes were observed for TC, HDL, or TG (P > 0.05), although changes were in the direction of benefit. No statistically significant changes occurred in body composition (P > 0.05).Conclusions Walking reduces LDL-C and TC/HDL-C in adults independent of changes in body composition.
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“Aerobic exercise is effective in improving lipid metabolism607–615).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [607]
In the citing paper
“Six reported a significant increase in HDL-C levels, which was the most frequently observed effect of exercise on serum lipids577, 607–613).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [607]
Citations
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2023 ESC guidelines for the management of cardiomyopathies
Arbelo, E., Protonotarios, A., Gimeno, J. R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C. R., Biagini, E., Blom, N. A., de Boer, R. A., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad194 · Cited by 2,844
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2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk
Eckel, R. H., Jakicic, J. M., Ard, J. D., de Jesus, J. M., Houston Miller, N., Hubbard, V. S., Lee, I.-M., Lichtenstein, A. H., Loria, C. M., Millen, B. E., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.11.003 · Cited by 1,160
Kinoshita, M., Yokote, K., Arai, H., Iida, M., Ishigaki, Y., Ishibashi, S., Umemoto, S., Egusa, G., Ohmura, H., Okamura, T., et al. (2018) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2017 · Cited by 813
Fruchart, J.-C., Sacks, F., Hermans, M. P., Assmann, G., Brown, W. V., Ceska, R., Chapman, M. J., Dodson, P. M., Fioretto, P., Ginsberg, H. N., et al. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.10.002 · Cited by 463
Metadata
- Authors
- Kelley, G.
- Affiliations
- West Virginia University (US)
- Corresponding author
- Kelley, G
- ORCID
- Kelley, G
- Venue
- Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2004-05
- Volume
- 38
- Issue
- 5
- Pages
- 651-661
- ISSN
- 0091-7435 (ISSN-L)
- OpenAlex
- W2040589021
- Cited by
- 148
- References
- 47
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 7 · 2022: 4 · 2021: 1 · 2020: 7 · 2019: 7 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 8 · 2014: 6 · 2013: 12 · 2012: 10
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (R01HL069802)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- walking, physical activity, lipids, lipoproteins, LDL cholesterol, total cholesterol, HDL cholesterol, triglycerides, TC/HDL-C ratio, body composition, cardiovascular risk factors
- MeSH terms
- Adult, Cholesterol, Female, Humans, Lipoproteins, Male, Middle Aged, Triglycerides, Randomized Controlled Trials as Topic, Walking
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