Cited by 123Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and EducationHealth Promotion and Cardiovascular Prevention

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A community based primary prevention programme for type 2 diabetes integrating identification and lifestyle intervention for prevention: the Let's Prevent Diabetes cluster randomised controlled trial

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Davies, Melanie J., Gray, Laura J., Troughton, Jacqui, Gray, Alastair, Tuomilehto, Jaakko, Farooqi, Azhar, Khunti, Kamlesh, Yates, Thomas·2016·Preventive Medicine

DOI 10.1016/j.ypmed.2015.12.012

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Abstract

Objectives Prevention of type 2 diabetes (T2DM) is a priority in healthcare, but there is a lack of evidence investigating how to effectively translate prevention research into a UK primary care setting. We assessed whether a structured education programme targeting lifestyle and behaviour change was effective at preventing progression to T2DM in people with pre-diabetes.Materials and methods Forty-four general practices were randomised to receive either standard care or a 6hour group structured education programme with an annual refresher course, and regular phone contact. Participants were followed up for 3years. The primary outcome was progression to T2DM.Results Eight hundred and eighty participants were included (36% female, mean age 64years, 16% ethnic minority group); 131 participants developed T2DM. There was a non-significant 26% reduced risk of developing T2DM in the intervention arm compared to standard care (HR 0.74, 95% CI 0.48, 1.14, p=0.18). The reduction in T2DM risk when excluding those who did not attend the initial education session was also non-significant (HR 0.65, 0.41, 1.03, p=0.07). There were statistically significant improvements in HbA1c (-0.06, -0.11, -0.01), LDL cholesterol (-0.08, -0.15, -0.01), sedentary time (-26.29, -45.26, -7.32) and step count (498.15, 162.10, 834.20) when data were analysed across all time points.Conclusions This study suggests that a relatively low resource, pragmatic diabetes prevention programme resulted in modest benefits to biomedical, lifestyle and psychosocial outcomes, however the reduction to the risk of T2DM did not reach significance. The findings have important implications for future research and primary care.

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The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
International physical activity questionnaire: 12-country reliability and validity
CRAIG, C. L., MARSHALL, A. L., SJ??STR??M, M., BAUMAN, A. E., BOOTH, M. L., AINSWORTH, B. E., PRATT, M., EKELUND, U., YNGVE, A., SALLIS, J. F., et al. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000078924.61453.fb · Cited by 21,619
Multiple Imputation for Nonresponse in Surveys
Rubin, D. B. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316696 · Cited by 20,701
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011 · cited 2×
“(5) Consistent findings have been reported from the USA Diabetes Prevention Program (DPP).(6)”
Background
Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle among Subjects with Impaired Glucose Tolerance
Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873 · cited 1×
“(4) For example, the Finnish Diabetes Prevention Study (DPS) found that the risk of T2DM was reduced by 58% in those referred to an intensive lifestyle intervention compared to usual care over a three-year period.(5) Consistent findings have been reported from the USA Diabetes Prevention Program (DPP).”
BackgroundSelf-citation
The Brief Illness Perception Questionnaire
Broadbent, E., Petrie, K. J., Main, J., & Weinman, J. (2006) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2005.10.020 · Cited by 3,431
How Many Steps/Day Are Enough?: Preliminary Pedometer Indices for Public Health
Tudor-Locke, C., & Bassett, D. R. (2004) · Sports Medicine · doi:10.2165/00007256-200434010-00001 · Cited by 2,054
The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
Ramachandran, A., Snehalatha, C., Mary, S., Mukesh, B., Bhaskar, A. D., Vijay, V., & Indian Diabetes Prevention Programme (IDPP) (2006) · Diabetologia · doi:10.1007/s00125-005-0097-z · Cited by 1,881
The Finnish Diabetes Prevention Study (DPS)
Lindström, J., Louheranta, A., Mannelin, M., Rastas, M., Salminen, V., Eriksson, J., Uusitupa, M., Tuomilehto, J., & for the Finnish Diabetes Prevention Study Group (2003) · Diabetes Care · doi:10.2337/diacare.26.12.3230 · Cited by 1,848
Self-citation
Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis
Gillies, C. L., Abrams, K. R., Lambert, P. C., Cooper, N. J., Sutton, A. J., Hsu, R. T., & Khunti, K. (2007) · BMJ · doi:10.1136/bmj.39063.689375.55 · Cited by 1,171
Self-citation
Estimating the current and future costs of Type 1 and Type 2 diabetes in the UK, including direct health costs and indirect societal and productivity costs
Hex, N., Bartlett, C., Wright, D., Taylor, M., & Varley, D. (2012) · Diabetic Medicine · doi:10.1111/j.1464-5491.2012.03698.x · Cited by 819
Multiple Imputation for Nonresponse in Surveys
Campion, W. M., & Rubin, D. B. (1989) · Journal of Marketing Research · doi:10.2307/3172772 · Cited by 775
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial
Davies, M. J., Heller, S. R., Skinner, T. C., Campbell, M. J., Carey, M., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., et al. (2008) · BMJ · doi:10.1136/bmj.39474.922025.be · Cited by 761
Self-citation
Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations
Dunkley, A. J., Bodicoat, D. H., Greaves, C. J., Russell, C., Yates, T., Davies, M. J., & Khunti, K. (2014) · Diabetes Care · doi:10.2337/dc13-2195 · Cited by 542
Self-citation
Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus
(2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2011.03.012 · Cited by 462
Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study
Roper, N. A., Bilous, R. W., Kelly, W. F., Unwin, N. C., & Connolly, V. M. (2001) · BMJ · doi:10.1136/bmj.322.7299.1389 · Cited by 316
Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial
Andrews, R., Cooper, A., Montgomery, A., Norcross, A., Peters, T., Sharp, D., Jackson, N., Fitzsimons, K., Bright, J., Coulman, K., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60442-x · Cited by 302
Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M., Campbell, M. J., Heller, S. R., Khunti, K., Skinner, T. C., & Davies, M. J. (2010) · BMJ · doi:10.1136/bmj.c4093 · Cited by 258
Self-citation
Dietary Intervention in Primary Care: Validity of the DINE Method for Diet Assessment
Roe, L. S., Strong, C., Whiteside, C., Neil, A., & Mant, D. (1994) · Family Practice · doi:10.1093/fampra/11.4.375 · Cited by 256
Progression rates from HbA1c 6.0-6.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis
Morris, D. H., Khunti, K., Achana, F., Srinivasan, B., Gray, L. J., Davies, M. J., & Webb, D. (2013) · Diabetologia · doi:10.1007/s00125-013-2902-4 · Cited by 229
Self-citation
Effectiveness of a Pragmatic Education Program Designed to Promote Walking Activity in Individuals With Impaired Glucose Tolerance
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Self-citation
Interpreting the results of secondary end points and subgroup analyses in clinical trials: should we lock the crazy aunt in the attic?
Freemantle, N. (2001) · BMJ · doi:10.1136/bmj.322.7292.989 · Cited by 168
Effect of a lifestyle intervention on weight change in south Asian individuals in the UK at high risk of type 2 diabetes: a family-cluster randomised controlled trial
Bhopal, R. S., Douglas, A., Wallia, S., Forbes, J. F., Lean, M. E. J., Gill, J. M. R., McKnight, J. A., Sattar, N., Sheikh, A., Wild, S. H., et al. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70204-3 · Cited by 149
Self-citation
A fifteen-dimensional measure of health-related quality of life (15D) and its applications
Sintonen, H., & Pekurinen, M. (1993) · Springer eBooks · doi:10.1007/978-94-011-2988-6_9 · Cited by 147
Quality of life assessment: Key issues in the 1990s
Aaronson, N. K. (1993) · Quality of Life Research · doi:10.1007/bf00434802 · Cited by 135
Uptake of the NHS Health Checks programme in a deprived, culturally diverse setting: cross-sectional study
Dalton, A. R. H., Bottle, A., Okoro, C., Majeed, A., & Millett, C. J. (2011) · Journal of Public Health · doi:10.1093/pubmed/fdr034 · Cited by 127
Randomised controlled trial evaluating lifestyle interventions in people with impaired glucose tolerance
Oldroyd, J. C., Unwin, N. C., White, M. J., Mathers, J. C., & Alberti, K. G. M. M. (2005) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2005.09.018 · Cited by 115
Rationale and design of the ADDITION-Leicester study, a systematic screening programme and Randomised Controlled Trial of multi-factorial cardiovascular risk intervention in people with Type 2 Diabetes Mellitus detected by screening
Webb, D. R., Khunti, K., Srinivasan, B. T., Gray, L. J., Taub, N. A., Campbell, S., Barnett, J., Henson, J. J., Hiles, S., Farooqi, A., et al. (2010) · Trials · doi:10.1186/1745-6215-11-16 · Cited by 82
Self-citation
Detection of impaired glucose regulation and/or type 2 diabetes mellitus, using primary care electronic data, in a multiethnic UK community setting
Gray, L. J., Davies, M. J., Hiles, S., Taub, N. A., Webb, D. R., Srinivasan, B. T., & Khunti, K. (2012) · Diabetologia · doi:10.1007/s00125-011-2432-x · Cited by 76
Self-citation
The EQ-5D Health-Related Quality of Life Questionnaire
(2012) · SpringerReference · doi:10.1007/springerreference_73334 · Cited by 72
Brief Illness Perception Questionnaire
Broadbent, E., Petrie, K. J., Main, J., & Weinman, J. A. (2006) · PsycTESTS Dataset · doi:10.1037/t10379-000 · Cited by 71
The fasting hyperglycaemia study: II. Randomized controlled trial of reinforced healthy-living advice in subjects with increased but not diabetic fasting plasma glucose
Dyson, P. A., Hammersley, M. S., Morris, R. J., Holman, R. R., & Turner, R. C. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90318-8 · Cited by 66
Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: the ADDITION-Leicester study
Webb, D. R., Gray, L. J., Khunti, K., Srinivasan, B. T., Taub, N. A., Campbell, S., Barnett, J., Farooqi, A., Echouffo-Tcheugui, J. B., Griffin, S. J., et al. (2011) · Diabetologia · doi:10.1007/s00125-011-2189-2 · Cited by 64
Self-citation
Let’s prevent diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation
Gray, L. J., Khunti, K., Williams, S., Goldby, S., Troughton, J., Yates, T. E., Gray, A. M., Davies, M. J., & Collaborators, F. T. L. P. (2012) · Cardiovascular Diabetology · doi:10.1186/1475-2840-11-56 · Cited by 38
Self-citation
Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance
Gray, L. J., Khunti, K., Edwardson, C. L., Goldby, S., Henson, J. J., Morris, D. H., Sheppard, D., Webb, D. R., Williams, S. T., Yates, T. E., et al. (2012) · Diabetologia · doi:10.1007/s00125-012-2725-8 · Cited by 38
Self-citation

Research works printed but not linked: 2

Aujla, 2010, Barriers to practice and patient recruitment to primary care based diabetes screening studies, Diabet. Med., 27, 371
Gillett M, Dallosso HM, Dixon S, Brennan A, Carey ME, Campbell MJ, et al. Delivering the Diabetes Education and Self Management for Ongoing and Newly Diagnosed (DESMOND) Programme for People with Newly Diagnosed Type 2 Diabetes: Cost Effectiveness Analysis 2010 2010-08-20 12:28:44. · DOI

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Barry, E., Roberts, S. A., Oke, J. L., Vijayaraghavan, S., Normansell, R., & Greenhalgh, T. (2017) · BMJ · doi:10.1136/bmj.i6538 · Cited by 347
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Hemmingsen, B., Gimenez-Perez, G., Mauricio, D., Roqué i Figuls, M., Metzendorf, M.-I., & Richter, B. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003054.pub4 · Cited by 316
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Authors: Davies, M. J., Gray, L. J., Troughton, J., Gray, A., Tuomilehto, J., Farooqi, A., Khunti, K., & Yates, T.
Affiliations: University of Leicester (GB)
University of Oxford (GB)
Universität für Weiterbildung Krems (AT)
Corresponding author: Gray, Laura J.
ORCID: Davies, Melanie J.
Gray, Laura J.
Troughton, Jacqui
Gray, Alastair
Tuomilehto, Jaakko
Khunti, Kamlesh
Yates, Thomas
Venue: Preventive Medicine
Publisher: Elsevier BV
Published: 2016-03
Volume: 84
Pages: 48-56
ISSN: 0091-7435 (ISSN-L)
DOI: 10.1016/j.ypmed.2015.12.012
OpenAlex: W2202989893
Cited by: 123
References: 36
Citations by year: 2026: 11 · 2025: 17 · 2024: 5 · 2023: 15 · 2022: 11 · 2021: 17 · 2020: 12 · 2019: 7 · 2018: 14 · 2017: 10 · 2016: 4
FWCI: 8.09
Type: journal article
Language: en
Open access: green
figshare.com
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Preventive Medicine (publishedVersion)
PubMed (publishedVersion)
Figshare (submittedVersion, cc-by-nc-nd)
Figshare (submittedVersion)
Leicester Research Archive (University of Leicester) (submittedVersion, cc-by-nc-nd)
Open Research Exeter (University of Exeter) (submittedVersion)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
Funders: University Hospitals of Leicester NHS Trust
National Institute for Health and Care Research (CL-2013-11-001, RP-PG-0606-1272, NF-SI-0512-10159, CDF-2012-05-259)
University of Leicester
Loughborough University
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: type 2 diabetes prevention, prediabetes, primary prevention, lifestyle intervention, structured education programme, behavior change, HbA1c, LDL cholesterol, sedentary behavior, physical activity, general practice, community-based prevention
MeSH terms: Adult, Aged, Diabetes Mellitus, Type 2, Female, United Kingdom, Health Promotion, Humans, Life Style, Male, Mass Screening, Middle Aged, Prediabetic State, Primary Prevention, Program Evaluation, Risk Reduction Behavior, Independent Living

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A community based primary prevention programme for type 2 diabetes integrating identification and lifestyle intervention for prevention: the Let's Prevent Diabetes cluster randomised controlled trial

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