An indirect method for the estimation of oxytocin blood concentration and half‐life in pregnant women near term
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Saameli calculated that the half-life of oxytocin in pregnant women was approximately 3-4 min, and that uterine contractions were initiated by infusions that raised plasma concentrations by 3 μU/ml (5 pg/ml).
“he calculated that the half‐life of oxytocin in pregnant women was approximately 3–4 min, and also that uterine contractions were initiated by infusions that raised plasma concentrations by 3 μU/ml (5 pg/ml).”
From Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers (2016) · cites this paper as [52]
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“Saameli (52) drew similar conclusions: he calculated that the half-life of oxytocin in pregnant women was approximately 3–4 min, and also that uterine contractions were initiated by infusions that raised plasma concentrations by 3 l U/ml (5 pg/ml).”
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- Authors
- Saameli, K.
- Affiliations
- Kantonsspital St. Gallen (CH)
- Corresponding author
- Saameli, Konrad
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1963-01
- Volume
- 85
- Issue
- 2
- Pages
- 186-192
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2283714092
- Cited by
- 34
- References
- 13
- Citations by year
- 2023: 1 · 2020: 1 · 2019: 1 · 2016: 1 · 2012: 1
- FWCI
- 3.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- oxytocin, blood concentration, half-life, indirect estimation, near-term pregnancy, labor induction, pharmacokinetics
- MeSH terms
- Female, Half-Life, Humans, Oxytocin, Pregnancy, Uterus, Term Birth
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