The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Microparticles in cardiovascular diseases
Abstract
Microparticles are membrane vesicles released from many different cell types. There are two mechanisms that can result in their formation, cell activation and apoptosis. In these two mechanisms, different pathways are involved in microparticle generation. Microparticle generation seems to be a well regulated process. Microparticles vary in size, phospholipid and protein composition. They have a potent pro-inflammatory effect, promote coagulation and affect vascular function. Since these processes are all involved in the pathogenesis of cardiovascular disease and circulating microparticle numbers are altered in many cardiovascular diseases, a role for microparticles in the pathogenesis of cardiovascular diseases is likely. Although hard evidence for a role of microparticles in cardiovascular diseases at present is still only limited, new evidence is accumulating rapidly to support this theory. Elucidation of the microparticle composition and the mechanisms involved in exertion of their effects will supply this evidence and enable us to develop additional intervention strategies for prevention and treatment of cardiovascular diseases.
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Cites
TCR Activation of Human T Cells Induces the Production of Exosomes Bearing the TCR/CD3/ζ Complex
Blanchard, N., Lankar, D., Faure, F., Regnault, A., Dumont, C., Raposo, G., & Hivroz, C. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.7.3235 · Cited by 660
Cellular origin and procoagulant properties of microparticles in meningococcal sepsis
Nieuwland, R., Berckmans, R. J., McGregor, S., Böing, A. N., Th. M. Romijn, F. P. H., Westendorp, R. G. J., Hack, C. E., & Sturk, A. (2000) · Blood · doi:10.1182/blood.v95.3.930.003k46_930_935 · Cited by 574
Self-citationVitamin C Inhibits Endothelial Cell Apoptosis in Congestive Heart Failure
Rössig, L., Hoffmann, J., Hugel, B., Mallat, Z., Haase, A., Freyssinet, J.-M., Tedgui, A., Aicher, A., Zeiher, A. M., & Dimmeler, S. (2001) · Circulation · doi:10.1161/hc4301.098284 · Cited by 182
Cited by
Ratajczak, J., Wysoczynski, M., Hayek, F., Janowska-Wieczorek, A., & Ratajczak, M. Z. (2006) · Leukemia · doi:10.1038/sj.leu.2404296 · Cited by 1,340
Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes
Zampetaki, A., Kiechl, S., Drozdov, I., Willeit, P., Mayr, U., Prokopi, M., Mayr, A., Weger, S., Oberhollenzer, F., Bonora, E., et al. (2010) · Circulation Research · doi:10.1161/circresaha.110.226357 · Cited by 1,283
Membrane Microparticles: Two Sides of the Coin
Hugel, B., Martínez, M. C., Kunzelmann, C., & Freyssinet, J.-M. (2005) · Physiology · doi:10.1152/physiol.00029.2004 · Cited by 698
Extracellular vesicles in physiological and pathological conditions
Yuana, Y., Sturk, A., & Nieuwland, R. (2013) · Blood Reviews · doi:10.1016/j.blre.2012.12.002 · Cited by 569
Self-citationTurturici, G., Tinnirello, R., Sconzo, G., & Geraci, F. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00228.2013 · Cited by 483
Metadata
- Authors
- VANWIJK, M., VANBAVEL, E., STURK, A., & NIEUWLAND, R.
- Venue
- Cardiovascular Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-08-01
- Volume
- 59
- Issue
- 2
- Pages
- 277-287
- ISSN
- 0008-6363 (ISSN-L)
- OpenAlex
- W2017269547
- Cited by
- 610
- References
- 3
- FWCI
- 7.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- VANWIJK, M., VANBAVEL, E., STURK, A., & NIEUWLAND, R. (2003). Microparticles in cardiovascular diseases. Cardiovascular Research. https://doi.org/10.1016/s0008-6363(03)00367-5
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
