The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Endogenous nitric oxide synthase inhibitors are responsible for the L‐arginine paradox
Abstract
L‐Arginine, the substrate of nitric oxide (NO) synthases (NOSs), is found in the mammalian organism at concentrations by far exceeding K M values of these enzymes. Therefore, additional L‐arginine should not enhance NO formation. In vivo, however, increasing L‐arginine concentration in plasma has been shown repeatedly to increase NO production. This phenomenon has been named the L‐arginine paradox; it has found no satisfactory explanation so far. In the present work, evidence for the hypothesis that the endogenous NOS inhibitors methylarginines, asymmetric dimethylarginine being the most powerful (IC 50 1.5 μM), are responsible for the L‐arginine paradox is presented.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Pyruvate dehydrogenase (887), α-ketoglutarate dehydrogenase (130, 887, 952), and monoamine oxygenase A and B (290) have all been demonstrated to serve as ROS sources.”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [952]
Citations
Cites
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
Leone, A., Moncada, S., Vallance, P., Calver, A., & Collier, J. (1992) · The Lancet · doi:10.1016/0140-6736(92)90865-z · Cited by 2,107
Böger, R. H., Bode-Böger, S. M., Szuba, A., Tsao, P. S., Chan, J. R., Tangphao, O., Blaschke, T. F., & Cooke, J. P. (1998) · Circulation · doi:10.1161/01.cir.98.18.1842 · Cited by 1,181
Self-citationNitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.
Förstermann, U., Closs, E. I., Pollock, J. S., Nakane, M., Schwarz, P., Gath, I., & Kleinert, H. (1994) · Hypertension · doi:10.1161/01.hyp.23.6.1121 · Cited by 1,122
L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.
Creager, M. A., Gallagher, S. J., Girerd, X. J., Coleman, S. M., Dzau, V. J., & Cooke, J. P. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115987 · Cited by 809
Drexler, H., Zeiher, A. M., Meinzer, K., & Just, H. (1991) · The Lancet · doi:10.1016/0140-6736(91)92372-9 · Cited by 794
Iyengar, R., Stuehr, D. J., & Marletta, M. A. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.18.6369 · Cited by 664
Böger, R. H., Bode‐Böger, S. M., Thiele, W., Junker, W., Alexander, K., & Frölich, J. C. (1997) · Circulation · doi:10.1161/01.cir.95.8.2068 · Cited by 490
Self-citationSurdacki, A., Nowicki, M. P., Sandmann, J., Tsikas, D., Boeger, R. H., Bode-Boeger, S. M., Kruszelnicka-Kwiatkowska, O., Kokot, F., Dubiel, J. S., & Froelich, J. C. (1999) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199904000-00020 · Cited by 422
Self-citationKakimoto, Y., & Akazawa, S. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)62716-4 · Cited by 409
Interference ofL-Arginine Analogues withL-Arginine Transport Mediated by the y+Carrier hCAT-2B
Closs, E. I., Basha, F. Z., Habermeier, A., & Förstermann, U. (1997) · Nitric Oxide · doi:10.1006/niox.1996.0106 · Cited by 385
Research works printed but not linked: 3
- Bode-Böger S.M., 1999, J. Invest. Med., 47, 43
- Sandmann J. (2000) Ph.D. thesis University of Hannover Hannover.
- Böger R.H., 2000, Naunyn-Schmiedeberg's Arch. Pharmacol., 361, R42
Cited by
Sorted by citations
Items 101–200 of 236
Arlouskaya, Y., Sawicka, A., Głowala, M., Giebułtowicz, J., Korytowska, N., Tałałaj, M., Nowicka, G., & Wrzosek, M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8060897 · Cited by 36
Haghikia, A., Kayacelebi, A. A., Beckmann, B., Hanff, E., Gold, R., Haghikia, A., & Tsikas, D. (2015) · Amino Acids · doi:10.1007/s00726-015-2015-0 · Cited by 36
Self-citationMaas, R., Wenske, S., Zabel, M., Ventura, R., Schwedhelm, E., Steenpaß, A., Klemm, H. U., Noldus, J., & Böger, R. H. (2005) · European Urology · doi:10.1016/j.eururo.2005.07.017 · Cited by 36
Self-citationNitric Oxide Regulation of Microvascular Oxygen
Buerk, D. G. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1551 · Cited by 36
Micelles Based on Lysine, Histidine, or Arginine: Designing Structures for Enhanced Drug Delivery
Li, X., Liu, R., Chen, X., He, M., Zhang, Y., & Chen, S. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.744657 · Cited by 35
Marteau, J., Mohr, S., Pfister, M., & Visvikis‐Siest, S. (2005) · Clinical Chemistry · doi:10.1373/clinchem.2005.048546 · Cited by 35
Asymmetric dimethylarginine predicts survival in the elderly
Pizzarelli, F., Maas, R., Dattolo, P. C. G., Tripepi, G. L., Michelassi, S., D’Arrigo, G., Mieth, M., Bandinelli, S., Ferrucci, L., & Zoccali, C. (2013) · AGE · doi:10.1007/s11357-013-9523-1 · Cited by 35
Tsikas, D. (2009) · Journal of Chromatography B · doi:10.1016/j.jchromb.2009.01.005 · Cited by 34
Self-citationAmino acids in human nutrition and health
D’Mello, J. P. F. (2011) · CABI eBooks · doi:10.1079/9781845937980.0000 · Cited by 36
Haghikia, A., Yanchev, G. R., Kayacelebi, A. A., Hanff, E., Bledau, N., Widera, C., Sonnenschein, K., Haghikia, A., Weißenborn, K., Bauersachs, J. K., et al. (2017) · Amino Acids · doi:10.1007/s00726-017-2409-2 · Cited by 33
Self-citationReduction in Basal Nitric Oxide Activity Causes Albuminuria
Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., & Schmieder, R. E. (2011) · Diabetes · doi:10.2337/db09-1630 · Cited by 31
Human blood platelets lack nitric oxide synthase activity
Böhmer, A., Gambaryan, S. P., & Tsikas, D. (2014) · Platelets · doi:10.3109/09537104.2014.974024 · Cited by 31
Self-citationSciacqua, A., Grillo, N., Quero, M., Sesti, G., & Perticone, F. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms131113804 · Cited by 31
Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?
Ellger, B., Langouche, L., Richir, M. C., Debaveye, Y. A., Vanhorebeek, I., van Leeuwen, P. A. M., & den Berghe, G. V. (2008) · Intensive Care Medicine · doi:10.1007/s00134-008-1118-4 · Cited by 31
Chobanyan-Jürgens, K., Thum, T., Suchy, M.-T., Zhu, B., Mitschke, A., Gutzki, F., Beckmann, B., Stichtenoth, D. O., & Tsikas, D. (2007) · Journal of Chromatography B · doi:10.1016/j.jchromb.2007.08.002 · Cited by 31
Self-citationBetz, B. B., Möller-Ehrlich, K., Kress, T., Kniepert, J., Schwedhelm, E., Böger, R. H., Wanner, C., Sauvant, C., & Schneider, R. (2013) · Translational research · doi:10.1016/j.trsl.2013.04.005 · Cited by 30
Self-citationKayacelebi, A. A., Willers, J., Pham, V. V., Hahn, A., Schneider, J. Y., Rothmann, S., Frölich, J. C., & Tsikas, D. (2015) · Amino Acids · doi:10.1007/s00726-015-1915-3 · Cited by 29
Self-citationKayacelebi, A. A., Minović, I., Hanff, E., Frenay, A.-R. S., de Borst, M. H., Feelisch, M., van Goor, H., Bakker, S. J. L., & Tsikas, D. (2017) · Amino Acids · doi:10.1007/s00726-017-2420-7 · Cited by 29
Self-citationVladimirova‐Kitova, L., Deneva, T., Angelova, E., Nikolov, F. P., Marinov, B. I., & Mateva, N. G. (2008) · Clinical Physiology and Functional Imaging · doi:10.1111/j.1475-097x.2008.00825.x · Cited by 29
Knipp, M. (2006) · ChemBioChem · doi:10.1002/cbic.200500527 · Cited by 28
Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria
Kanzelmeyer, N. K., Tsikas, D., Chobanyan-Jürgens, K., Beckmann, B., Vaske, B., Illsinger, S., Das, A. M., & Lücke, T. (2011) · Amino Acids · doi:10.1007/s00726-011-0892-4 · Cited by 27
Self-citationTsikas, D. (2017) · Journal of Controversies in Biomedical Research · doi:10.15586/jcbmr.2017.22 · Cited by 26
Self-citationBrain nitric oxide: Regional characterisation of a real-time microelectrochemical sensor
Finnerty, N. J., O’Riordan, S. L., Pålsson, E., & Lowry, J. P. (2012) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2012.05.023 · Cited by 26
Pascale, V., Pascale, W., Lavanga, V., Sansone, V. C., Ferrario, P., & Colonna, V. D. G. (2013) · Medical Science Monitor · doi:10.12659/msm.889275 · Cited by 26
Lücke, T., Kanzelmeyer, N. K., Chobanyan-Jürgens, K., Tsikas, D., Franke, D., Kemper, M. J., Ehrich, J. H. H., & Das, A. M. (2007) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfm761 · Cited by 27
Self-citationMcCarty, M. F. (2004) · Medical Hypotheses · doi:10.1016/j.mehy.2002.11.008 · Cited by 26
Baskal, S., Bollenbach, A., Mels, C. M. C., Kruger, R., & Tsikas, D. (2021) · Amino Acids · doi:10.1007/s00726-021-03031-6 · Cited by 25
Self-citationNitric oxide and iron metabolism in exercised rat with L-arginine supplementation
Xiao, D.-S., Jiang, L., Che, L.-L., & Lu, L. (2003) · Molecular and Cellular Biochemistry · doi:10.1023/a:1025517216681 · Cited by 25
Martens‐Lobenhoffer, J., Schwedhelm, E., & Tsikas, D. (2009) · Journal of Chromatography B · doi:10.1016/j.jchromb.2009.07.003 · Cited by 25
Self-citationPilz, S., Putz‐Bankuti, C., Meinitzer, A., März, W., Kienreich, K., Stojaković, T., Pieber, T. R., & Stauber, R. E. (2015) · Amino Acids · doi:10.1007/s00726-015-2000-7 · Cited by 23
Abdelhamed, A., Reís, S. E., Sane, D. C., Brosnihan, K. B., Preli, R. B., & Herrington, D. M. (2003) · American Heart Journal · doi:10.1067/mhj.2003.160 · Cited by 24
Amrouni, D., Meiller, A., Gautier, S. M., Piraud, M., Bouteille, B., Vincendeau, P., Buguet, A., & Cespuglio, R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016891 · Cited by 22
Nitric-Oxide-Mediated Signaling in Podocyte Pathophysiology
Semenikhina, M., Stefanenko, M., Spires, D. R., Ilatovskaya, D. V., & Palygin, O. (2022) · Biomolecules · doi:10.3390/biom12060745 · Cited by 21
The Metabolic Coupling of Arginine Metabolism to Nitric Oxide Generation by Astrocytes
Gensert, J. M., & Ratan, R. R. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.919 · Cited by 21
Jiang, Z., Shi, X., Zhao, H., Si, J., & Nuttall, A. L. (2004) · Hearing Research · doi:10.1016/s0378-5955(03)00398-8 · Cited by 21
Buttner, P. G., Werner, S., Baskal, S., Tsikas, D., Adams, V., Lurz, P. C., Besler, C., Knauth, S., Bahls, M., Schwedhelm, E., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-00216-7 · Cited by 20
Self-citationKhan, B. V., Rahman, S. T., Haque, T., Merchant, N., Bhaheetharan, S., Harris, J., Umar, K., Wahi, J. E., & Ferdinand, K. C. (2012) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248412436607 · Cited by 20
Mitochondrial nitric oxide inhibits ATP synthesis Effect of free calcium in rat heart
Saavedra‐Molina, A., Ramı́rez-Emiliano, J., Clemente‐Guerrero, M., Pérez‐Vázquez, V., Aguilera-Aguirre, L., & González‐Hernández, J. C. (2003) · Amino Acids · doi:10.1007/s00726-002-0331-7 · Cited by 20
Reactive Metabolites and AGE-RAGE-Mediated Inflammation in Patients following Liver Transplantation
Brenner, T., Fleming, T. H., Spranz, D. M., Schemmer, P., Bruckner, T. M., Uhle, F., Martin, E., Weigand, M. A., & Hofer, S. (2013) · Mediators of Inflammation · doi:10.1155/2013/501430 · Cited by 19
Nellore, K., & Harris, N. R. (2002) · Microcirculation · doi:10.1038/sj.mn.7800162 · Cited by 20
Hanusch, B., Sinningen, K., Brinkmann, F., Dillenhöfer, S., Frank, M., Jöckel, K., Koerner‐Rettberg, C., Holtmann, M. H., Legenbauer, T., Langrock, C., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042136 · Cited by 19
Self-citationDoroszko, A., Andrzejak, R., & Szuba, A. (2010) · Hypertension Research · doi:10.1038/hr.2010.169 · Cited by 19
Tsikas, D. (2008) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3283065bb1 · Cited by 18
Self-citationLücke, T., Tsikas, D., Kanzelmeyer, N. K., Vaske, B., & Das, A. M. (2006) · Metabolism · doi:10.1016/j.metabol.2006.07.020 · Cited by 18
Self-citationTsikas, D., Bollenbach, A., & Savvidou, M. D. (2017) · Amino Acids · doi:10.1007/s00726-017-2522-2 · Cited by 18
Self-citationBollenbach, A., Huneau, J., Mariotti, F., & Tsikas, D. (2019) · Nutrients · doi:10.3390/nu11071463 · Cited by 18
Self-citationJansen, K., Hanusch, B., Pross, S., Hanff, E., Drabert, K., Bollenbach, A., Dugave, I., Carmann, C., Siefen, R. G., Emons, B., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9010175 · Cited by 18
Self-citationGündüz, Ö., Karadağ, Ç. H., & Ulugöl, A. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0443-2 · Cited by 18
Serum asymmetric dimethylarginine and nitric oxide levels in obese postmenopausal women
Koçak, H., Öner-İyidoğan, Y., Gürdöl, F., Öner, P., & Esin, D. (2011) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.20452 · Cited by 18
Medeiros, R. F., Gaique, T. G., Bento‐Bernardes, T., Kindlovits, R., Gomes, T. M. B., Motta, N. A. V., Brito, F. C., Fernandes‐Santos, C., Oliveira, K. J., & da Nóbrega, A. C. L. (2017) · British Journal Of Nutrition · doi:10.1017/s0007114517001702 · Cited by 20
Berlinguer, F., Porcu, C., Molle, G., Cabiddu, A., Dattena, M., Gallus, M., Pasciu, V., Succu, S., Sotgiu, F. D., Paliogiannis, P., et al. (2019) · Animals · doi:10.3390/ani10010065 · Cited by 17
Sitar, M. E., Kayacelebi, A. A., Beckmann, B., Kielstein, J. T., & Tsikas, D. (2015) · Amino Acids · doi:10.1007/s00726-015-1991-4 · Cited by 17
Self-citationSenbel, A. M., Omar, A. G., Moneim, L. M. A., Mohamed, H. F., & Daabees, T. T. (2014) · Pharmacological Reports · doi:10.1016/j.pharep.2014.06.013 · Cited by 17
Garcia, V. P., Rocha, H. N. M., Silva, G. M., do Amaral, T. A. G., Secher, N. H., da Nóbrega, A. C. L., Vianna, L. C., & Rocha, N. G. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.06.006 · Cited by 17
Platelet aggregation in arterial hypertension: Is there a nitric oxide–urea connection?
Moss, M. B., Siqueira, M. A. S., Mann, G. E., Brunini, T. M. C., & Mendes‐Ribeiro, A. C. (2009) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2009.05247.x · Cited by 17
Hara, S., Mukai, T., Kurosaki, K., Mizukami, H., Kuriiwa, F., & Endo, T. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.05.055 · Cited by 17
Böhmer, A., Gambaryan, S. P., Flentje, M., Jordan, J., & Tsikas, D. (2014) · Journal of Chromatography B · doi:10.1016/j.jchromb.2014.06.025 · Cited by 15
Self-citationNakaki, T., & Hishikawa, K. (2002) · Folia Pharmacologica Japonica · doi:10.1254/fpj.119.7 · Cited by 15
Günes, D. N., Kayacelebi, A. A., Hanff, E., Lundgren, J., Redfors, B., & Tsikas, D. (2017) · Amino Acids · doi:10.1007/s00726-017-2465-7 · Cited by 15
Self-citationBollenbach, A., Hanff, E., Brunner, G. H. G., & Tsikas, D. (2019) · Amino Acids · doi:10.1007/s00726-019-02737-y · Cited by 15
Self-citationBuck, A., Kayacelebi, A. A., Chobanyan-Jürgens, K., Illsinger, S., Bohnhorst, B., Beckmann, B., Hanff, E., Das, A. M., Tsikas, D., & Lücke, T. (2017) · Amino Acids · doi:10.1007/s00726-017-2382-9 · Cited by 15
Self-citationKozlov, A. V., Sobhian, B., Costantino, G., Nohl, H., Redl, H., & Bahrami, S. (2001) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(01)00047-3 · Cited by 15
Role of intramitochondrial nitric oxide in rat heart and kidney during hypertension
Aguilera-Aguirre, L., González‐Hernández, J. C., Pérez‐Vázquez, V., Ramı́rez-Emiliano, J., Clemente‐Guerrero, M., Villalobos‐Molina, R., & Saavedra‐Molina, A. (2002) · Mitochondrion · doi:10.1016/s1567-7249(02)00002-8 · Cited by 15
Amin, H. J., Soraisham, A. S., & SAUVE, R. S. (2009) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2008.01458.x · Cited by 14
Brouwers, O., Teerlink, T., van Bezu, J. S. M., Barto, R., Stehouwer, C. D. A., & Schalkwijk, C. G. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1433.017 · Cited by 14
Deveaux, A., Fouillet, H., Petzke, K. J., Hermier, D., André, E., Bunouf, P., Lantoine, F., Benamouzig, R., Mathé, V., Huneau, J., et al. (2016) · Journal of Nutrition · doi:10.3945/jn.116.231910 · Cited by 15
Plasma Arginine and Urinary Nitrate and Nitrite Excretion in Bronchopulmonary Dysplasia
Heckmann, M., Kreuder, J. G., Riechers, K., Tsikas, D., Boedeker, R. H., Reiss, I. K. M., & Gortner, L. (2003) · Neonatology · doi:10.1159/000075377 · Cited by 14
Self-citationVladimirova‐Kitova, L., & Deneva-Koycheva, T. I. (2011) · Vascular Pharmacology · doi:10.1016/j.vph.2011.10.004 · Cited by 12
l -Arginine Transport in the Human Coronary and Peripheral Circulation
Miner, S. E. S., Al‐Hesayen, A., Kelly, S., Benson, T., Thiessen, J. J., Young, V. R., & Parker, J. D. (2004) · Circulation · doi:10.1161/01.cir.0000118469.77718.3e · Cited by 12
Les pharmaconutriments azotés : du tube à essai à la pratique clinique
Cynober, L. (2001) · Nutrition Clinique et Métabolisme · doi:10.1016/s0985-0562(01)00060-7 · Cited by 12
Patel, J. J., Hurt, R. T., McClave, S. A., & Martindale, R. G. (2017) · Critical Care Clinics · doi:10.1016/j.ccc.2016.12.006 · Cited by 36
Tsikas, D., Engeli, S., Beckmann, B., & Jordan, J. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.12.005 · Cited by 11
Self-citationNagasaka, H., Okano, Y., Aizawa, M., Miida, T., Yorifuji, T., Tajima, G., Sakura, N., Takatani, T., Sanayama, Y., Sugamoto, K., et al. (2009) · Metabolism · doi:10.1016/j.metabol.2009.07.013 · Cited by 11
Desrois, M., Caus, T., Belles, P. M., Dalmasso, C., Lan, C., Cozzone, P. J., & Bernard, M. (2007) · Transplant International · doi:10.1111/j.1432-2277.2007.00602.x · Cited by 11
Magné, J., Huneau, J., Borderie, D., Mathé, V., Bos, C., & Mariotti, F. (2015) · Amino Acids · doi:10.1007/s00726-015-1959-4 · Cited by 11
Arginine supplementation for neonatal necrotizing enterocolitis: are we ready?
Neu, J. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507691612 · Cited by 11
Tsikas, D., & Kinzel, M. (2017) · Hellenic Journal of Cardiology · doi:10.1016/j.hjc.2017.10.004 · Cited by 11
Self-citationBrinkmann, F., Hanusch, B., Ballmann, M., Mayorandan, S., Bollenbach, A., Chobanyan-Jürgens, K., Jansen, K., Choudhury, A. R., Derichs, N., Tsikas, D., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9062012 · Cited by 11
Self-citationGajewiak, J., Tsukahara, R., Tsukahara, T., Yu, S., Lu, Y., Murph, M. M., Mills, G. B., Tigyi, G., & Prestwich, G. D. (2007) · ChemMedChem · doi:10.1002/cmdc.200700111 · Cited by 11
Hanusch, B., Brinkmann, F., Mayorandan, S., Chobanyan-Jürgens, K., Wiemers, A., Jansen, K., Ballmann, M., Choudhury, A. R., Bollenbach, A., Derichs, N., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123802 · Cited by 10
Self-citationTetrahydrobiopterin in the vascular system
Walter, R. B., Schaffner, A., & Schoedon, G. (2001) · Pteridines · doi:10.1515/pteridines.2001.12.3.93 · Cited by 10
Sinningen, K., Emons, B., Böhme, P., Juckel, G., Hanusch, B., Beckmann, B., Tsikas, D., & Lücke, T. (2023) · Nitric Oxide · doi:10.1016/j.niox.2023.06.006 · Cited by 9
Self-citationHuman hemoglobin does not contain asymmetric dimethylarginine (ADMA)
Böhmer, A., Großkopf, H., Jordan, J., & Tsikas, D. (2012) · Nitric Oxide · doi:10.1016/j.niox.2012.03.013 · Cited by 9
Self-citationChen, B., Strauch, K., Jin, Y., Cui, H., Nelin, L. D., & Chicoine, L. G. (2014) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12252 · Cited by 9
Role of nitric oxide in ethanol-induced ascorbic acid release in striatum of freely moving mice
Yan, P. G., Wu, C. F., Huang, M., & Liu, W. (2003) · Toxicology Letters · doi:10.1016/s0378-4274(03)00260-1 · Cited by 9
Jing, Z., Kuang, L., Liu, N., & Yang, J. (2015) · Bioanalysis · doi:10.4155/bio.15.58 · Cited by 8
İritaş, S. B., Dip, A., Gündüzöz, M., Tutkun, L., Türksoy, V. A., Deniz, S., Tekin, G., OZTAN, O., & Ünlü, A. (2019) · International Journal of Environmental Health Research · doi:10.1080/09603123.2019.1628927 · Cited by 8
Effect of exogenous and endogenous nitric oxide on biofilm formation by Lactobacillus plantarum
Рашидовна, Я. Д., Вакатова, Л. В., Krivoruchko, A. V., Rubtsova, E. V., & Ilinskaya, O. N. (2013) · Microbiology · doi:10.1134/s0026261713040140 · Cited by 8
Zwemer, C. F., Davenport, R. D., Gómez-Espina, J., Blanco‐González, E., Whitesall, S. E., & D’Alecy, L. G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119991 · Cited by 8
Do We Have Unrealistic Expectations of the Potential of Immuno-Nutrition?
Cynober, L. (2001) · Canadian Journal of Applied Physiology · doi:10.1139/h2001-040 · Cited by 8
Cvetković, T., Pavlović, R., Đorđević, V. B., Stojanović, I. R., Veličković‐Radovanović, R., Ignjatović, A., STEFANOVIĆ, N. Z., Živanović, S. C., & Đorđević, V. (2012) · Journal of Medical Biochemistry · doi:10.2478/v10011-012-0029-7 · Cited by 6
L-Arginine in Nutrition: Multiple Beneficial Effects in the Etiopathology of Diabetes
Stančić, A., Korać, A., Buzadžić, B., Otašević, V., Janković, A., Vučetić, M., & Korać, B. (2013) · Journal of Nutritional Therapeutics · doi:10.6000/1929-5634.2012.01.02.3 · Cited by 7
Modeling gas phase nitric oxide release in lung epithelial cells
Jiang, J., & George, S. C. (2011) · Nitric Oxide · doi:10.1016/j.niox.2011.04.010 · Cited by 7
Czarnecka, A. M., Aleksandrowicz, M., Jasiński, K., Jaźwiec, R., Kalita, K., Hilgier, W., & Zielińska, M. (2018) · Journal of Neurochemistry · doi:10.1111/jnc.14578 · Cited by 7
The Additive Antinociceptive Effect of Resveratrol and Ketorolac in the Formalin Test in Mice
Rojas-Aguilar, F. A., Briones-Aranda, A., Jaramillo‐Morales, O. A., Romero‐Nava, R., Esquinca-Avilés, H. A., & Espinosa‐Juárez, J. V. (2023) · Pharmaceuticals · doi:10.3390/ph16081078 · Cited by 7
Kozlov, A. V., Sobhian, B., Duvigneau, J. C., Costantino, G., Gemeiner, M., Nohl, H., Redl, H. R., & Bahrami, S. (2002) · Journal of Laboratory and Clinical Medicine · doi:10.1067/mlc.2002.128180 · Cited by 7
Excess l-arginine restores endothelium-dependent relaxation impaired by monocrotaline pyrrole
Cheng, W., Oike, M., Hirakawa, M., Ohnaka, K., Koyama, T., & Ito, Y. (2005) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2005.01.002 · Cited by 6
Bollenbach, A., & Tsikas, D. (2018) · Amino Acids · doi:10.1007/s00726-018-2684-6 · Cited by 6
Self-citationGroßkopf, H., Böhmer, A., & Tsikas, D. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00449.2012 · Cited by 6
Self-citationFidanboylu, M., & Thomas, S. A. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305318 · Cited by 5
Metadata
- Authors
- Tsikas, D., Böger, R. H., Sandmann, J., Bode-Böger, S. M., & Frölich, J. C.
- Affiliations
- Medizinische Hochschule Hannover (DE)
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2000-07-24
- Volume
- 478
- Issue
- 1-2
- Pages
- 1-3
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2000940740
- Cited by
- 237
- References
- 38
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 6 · 2019: 9 · 2018: 4 · 2017: 11 · 2016: 3 · 2015: 16 · 2014: 6 · 2013: 10 · 2012: 11
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer-related gene regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Keywords
- nitric oxide synthase inhibitors, asymmetric dimethylarginine, methylarginines, nitric oxide production, L-arginine
- MeSH terms
- Animals, Arginine, Binding, Competitive, Enzyme Inhibitors, Humans, Kinetics, Models, Biological, Thermodynamics, Meta-Analysis as Topic, Nitric Oxide Synthase, omega-N-Methylarginine, Inhibitory Concentration 50, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review