The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
Open accessAbstract
The efficient delivery of short interfering RNAs (siRNAs) into cells provides a powerful approach to study cellular functions. SiRNAs were coupled to the membrane permeant peptides (MPPs) penetratin and transportan to improve their uptake by cells. Thiol‐containing siRNAs corresponding to luciferase, or green fluorescent protein (GFP) transgenes, were synthesized and conjugated to penetratin or transportan via a disulfide bond that is labile in the reducing environment of the cytoplasm. These MPP‐siRNAs efficiently reduced transient and stable expression of reporter transgenes in several mammalian cell types in a high proportion of cells, and demonstrated equivalent or better delivery characteristics than cationic liposomes with fewer manipulations.
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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., & Tuschl, T. (2001) · Nature · doi:10.1038/35078107 · Cited by 9,456
Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi
Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., & Hannon, G. J. (2001) · Science · doi:10.1126/science.1064023 · Cited by 1,580
High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates
Josephson, L., Tung, C.-H., Moore, A., & Weissleder, R. (1999) · Bioconjugate Chemistry · doi:10.1021/bc980125h · Cited by 882
Lindgren, M., Hällbrink, M., Prochiantz, A., & Langel, Ü. (2000) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)01447-4 · Cited by 803
Schwarze, S. R., & Dowdy, S. F. (2000) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01429-7 · Cited by 452
Antisense RNA: Function and Fate of Duplex RNA in Cells of Higher Eukaryotes
Kumar, M., & Carmichael, G. G. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1415-1434.1998 · Cited by 320
RNA interference: genetic wand and genetic watchdog
Bosher, J. M., & Labouesse, M. (2000) · Nature Cell Biology · doi:10.1038/35000102 · Cited by 313
Cargo delivery kinetics of cell-penetrating peptides
Hällbrink, M., Florén, A., Elmquist, A., Pooga, M., Bartfai, T., & Langel, Ü. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00398-4 · Cited by 312
Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival
Muratovska, A., Zhou, C., He, S., Goodyer, P., & Eccles, M. R. (2003) · Oncogene · doi:10.1038/sj.onc.1206766 · Cited by 248
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