The DOI matches its Crossref record; 26 of the 27 references it cites were found in a registry or an index.
Basal and stimulated secretion of cytokines by peritoneal macrophages in women with endometriosis
Open accessAbstract
Objective To evaluate basal (constitutive) and stimulated synthesis of tumor necrosis factor alpha (TNF alpha), interleukin (IL)-8, IL-10 by peritoneal macrophages (PM) in women with endometriosis.Design Peritoneal macrophages were cultured in the presence or absence of lipopolysaccharide (LPS) for 24 hours. Peritoneal fluids (PF) and PM supernatants were assayed for cytokines using ELISA.Setting Institute for the Study and Treatment of Endometriosis and university-based research laboratories.Subjects Fertile controls undergoing tubal ligation (n = 8) and women with endometriosis (n = 17).Intervention Peritoneal fluid samples were obtained at the time of diagnostic laparoscopy (endometriosis group) or laparoscopy for tubal ligation; both were performed in the midluteal phase of the cycle.Results Both basal and LPS stimulated production of TNF alpha, IL-8, and IL-10 by the PM were elevated significantly in women with endometriosis as compared with the fertile controls.Conclusions This study demonstrated that cytokines TNF alpha, IL-8, and IL-10 are synthesized at greater than normal levels by basal and stimulated PM from women with endometriosis. The levels of TNF alpha and IL-8 correlated with the levels in the PF, suggesting that PM are the principal source of these cytokines in the PF.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Implantation in the peritoneum is explained by a local disorder of the mechanisms that prevent adhesion. The consequence is an increased production of cytokine macrophages, including tumor necrosis factor α (TNF-α) and interleukin [55].”
From Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature) (2021) · cites this paper as [55]
Citations
Cites
Interleukin-10-deficient mice develop chronic enterocolitis
Kühn, R., Löhler, J., Rennick, D. M., Rajewsky, K., & Müller, W. (1993) · Cell · doi:10.1016/0092-8674(93)80068-p · Cited by 4,248
de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., & de Vries, J. E. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.5.1209 · Cited by 3,762
Interleukin-8 as a macrophage-derived mediator of angiogenesis
Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G., & Strieter, R. M. (1992) · Science · doi:10.1126/science.1281554 · Cited by 2,135
Revised American Fertility Society Classification of Endometriosis: 1985
(1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48430-x · Cited by 1,803
The Biology Of Cachectin/TNF: A Primary Mediator Of The Host Response
Beutler, B., & Cerami, A. (1989) · Annual Review of Immunology · doi:10.1146/annurev.iy.07.040189.003205 · Cited by 1,690
Cachectin and tumour necrosis factor as two sides of the same biological coin
Beutler, B., & Cerami, A. (1986) · Nature · doi:10.1038/320584a0 · Cited by 1,633
Properties and Functions of Interleukin-10
Mosman, T. R. (1994) · Advances in immunology · doi:10.1016/s0065-2776(08)60449-6 · Cited by 495
Interleukin‐1: A possible role in the infertility associated with endometriosis
Fakih, H., Baggett, B., & Holtz, G. (1988) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(88)90224-x · Cited by 319
Halme, J. K., Becker, S., & Haskill, S. (1987) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(87)90333-4 · Cited by 289
Interleukin-1: a possible role in the infertility associated with endometriosis
Fakih, H., Baggett, B., Holtz, G., Tsang, K.-Y., Lee, J. C., & Williamson, H. O. (1987) · Fertility and Sterility · doi:10.1016/s0015-0282(16)49993-0 · Cited by 285
Cited by
Sorted by citations
Pathogenesis and pathophysiology of endometriosis
Burney, R. O., & Giudice, L. C. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.06.029 · Cited by 1,590
“In women with endometriosis, the peritoneal fluid is remarkable for an increased number of activated macrophages and important differences in the cytokine/chemokine profile (78).”
Nisolle, M., & Donnez, J. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00191-x · Cited by 1,279
Endometriosis and infertility: pathophysiology and management
de Ziegler, D., Borghese, B., & Chapron, C. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60490-4 · Cited by 853
Endometriosis: epidemiology and aetiological factors
Viganò, P., Parazzini, F., Somigliana, E., & Vercellini, P. (2004) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2004.01.007 · Cited by 718
Role of cytokines in endometriosis
Harada, T., Iwabe, T., & Terakawa, N. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01816-7 · Cited by 567
Metadata
- Authors
- Rana, N., Braun, D. P., House, R., Gebel, H., Rotman, C., & Dmowski, W. P.
- Affiliations
- Rush University Medical Center (US)
- ORCID
- Gebel, Howard
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 1996-05
- Volume
- 65
- Issue
- 5
- Pages
- 925-930
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W98713221
- Cited by
- 264
- References
- 27
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 12 · 2023: 9 · 2022: 5 · 2021: 8 · 2020: 6 · 2019: 5 · 2018: 6 · 2017: 9 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 8 · 2012: 9
- FWCI
- 11.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01ca058922-03)
- National Cancer Institute (CA 58922)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Health Sciences › Medicine › Infectious Diseases › Diagnosis and treatment of tuberculosis
- Keywords
- endometriosis, peritoneal macrophages, cytokine production, TNF-α, interleukin-8, IL-10, lipopolysaccharide stimulation, peritoneal fluid
- MeSH terms
- Ascitic Fluid, Cells, Cultured, Endometriosis, Female, Humans, Lipopolysaccharides, Tumor Necrosis Factor-alpha, Cytokines, Interleukin-8, Interleukin-10, Macrophages, Peritoneal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
