Cited by 69Lipid metabolism and disordersLipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

Preheparin serum lipoprotein lipase mass level: the effects of age, gender, and types of hyperlipidemias

Watanabe, Hitoshi, Miyashita, Yoh, Murano, Takeyoshi, Hiroh, Yuhji, Itoh, Yoshiaki, Shirai, Kohji·1999·Atherosclerosis

Abstract

To clarify the factors regulating preheparin serum lipoprotein lipase mass (preheparin LPL mass), the correlations between preheparin LPL mass and age, gender and types of hyperlipidemias were investigated in 377 persons who underwent annual health examinations. Preheparin LPL mass level did not significantly differ in individuals from 19 to 70 years old, for both men and women. Preheparin LPL mass level correlated negatively with triglyceride (TG), positively with high density lipoprotein-cholesterol (HDL-C), and not at all with total cholesterol (TC) or low density lipoprotein-cholesterol (LDL-C). Preheparin LPL mass levels were apparently higher in women than in men, but when serum lipid levels were adjusted, preheparin LPL mass levels were identical. In type IV and IIb hyperlipidemia, preheparin LPL mass levels were lower than in type IIa patients and in normals. Remnant positive individuals had lower levels of preheparin LPL mass than the negative individuals. In conclusion, preheparin LPL mass levels were not affected by aging and gender, but were lower in the conditions in which TG catabolism was disturbed, indicating that preheparin LPL mass might reflect somewhat the amount of LPL working in the body.

Integrity signals

Registry

Crossref · 10.1016/s0021-9150(99)00012-x

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Pre-heparin LPL concentration indicates the amount of systemic LPL activity.

    “However, with several findings showing that pre-heparin LPL concentration indicate the amount of systemic LPL activity [64–66], Tanaka et al. turned the target to pre-heparin LPL, and found that 12 weeks of jogging training increased pre-heparin LPL concentrations in overweight men [67].”

    From Effects of aerobic exercise on lipids and lipoproteins (2017) · cites this paper as [66]

Cites

Flagged first, then by citations

1 of the 24 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Watanabe, H., Miyashita, Y., Murano, T., Hiroh, Y., Itoh, Y., & Shirai, K.
Affiliations
Toho University (JP)
Corresponding author
Shirai, Kohji
Venue
Atherosclerosis
Publisher
Elsevier BV
Published
1999-07
Volume
145
Issue
1
Pages
45-50
ISSN
0021-9150 (ISSN-L)
OpenAlex
W2107020693
Cited by
69
References
24
Citations by year
2025: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 2 · 2013: 1
FWCI
2.18
Type
journal article
Language
en
Open access
closed
Locations
  • Atherosclerosis (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
Keywords
lipoprotein lipase, hyperlipidemia, triglyceride catabolism, HDL cholesterol, age and sex differences, remnant lipoproteins, type IV hyperlipidemia, type II hyperlipidemia, lipoprotein lipase activity
MeSH terms
Adult, Age Factors, Aged, Cholesterol, Female, Heparin, Humans, Hyperlipidemias, Lipoprotein Lipase, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Sex Factors, Triglycerides

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review