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Cited by 266

The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.

A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins.

Open access
de Silva, H V, Stuart, W D, Duvic, C R, Wetterau, J R, Ray, M J, Ferguson, D G, Albers, H W, Smith, W R, Harmony, J A·1990·Journal of Biological Chemistry
DOI 10.1016/s0021-9258(19)38290-0
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Abstract

A new apolipoprotein, termed apolipoprotein J (apoJ), was purified from human plasma by immunoaffinity chromatography. ApoJ is a glycoprotein consisting of disulfide-linked subunits of 34-36 and 36-39 kDa. Each subunit is glycosylated and has a pI range of 4.9-5.4. ApoJ exists in the plasma associated with high density lipoproteins (HDL) and specifically with subclasses of HDL which also contain apoAI and cholesteryl ester transfer protein activity. Immunoaffinity purified apoJ-HDL subclasses have apparent molecular masses of 80, 160, 240, 340, and 520 kDa, as determined by gradient gel electrophoresis. By negative staining electron microscopy, apoJ-HDL range in diameter from 5 to 16 nm. Fractionation of plasma by vertical gradient density centrifugation revealed apoJ-HDL in HDL2 (d 1.063-1.125 g/ml) with the majority overlapping HDL3 (d 1.125-1.21 g/ml) and very high density lipoprotein (d 1.21-1.25 g/ml). The bimodal density distribution of apoJ-HDL suggests that these subclasses have a unique metabolic relationship and may play a role in the transport of cholesterol from peripheral tissues to the liver.

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Metadata

Authors
de Silva, H. V., Stuart, W. D., Duvic, C. R., Wetterau, J. R., Ray, M. J., Ferguson, D. G., Albers, H. W., Smith, W. R., & Harmony, J. A.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1990-08
Volume
265
Issue
22
Pages
13240-13247
ISSN
0021-9258 (ISSN-L)
DOI
10.1016/s0021-9258(19)38290-0
OpenAlex
W1578820077
Cited by
266
References
68
FWCI
15.73
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins. https://app.cochat.ai/papers/10.1016/s0021-9258(19)38290-0
The paper
de Silva, H. V., Stuart, W. D., Duvic, C. R., Wetterau, J. R., Ray, M. J., Ferguson, D. G., Albers, H. W., Smith, W. R., & Harmony, J. A. (1990). A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)38290-0

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.