On-line coupling of high-performance liquid chromatography and nuclear magnetic resonance
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NMR-flow-through cells introduced in 1979 allowed complex mixtures to be injected into NMR without pre-purification.
“This changed with the dawn of NMR-flow-through cells in 1979;130 here complex mixtures can be injected into the NMR without pre-purification, as the HPLC system served as online purification system.”
From Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products (2024) · cites this paper as [130]
Cites
Liquid chromatograph—mass spectrometer—computer analytical systems
Horning, E. C., Carroll, D. I., Dzidic, I., et al. (1974) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)90841-0 · Cited by 175 · see citing works
Interface for on-line liquid chromatography—mass spectroscopy analysis
Scott, R. P. W., SCOTT, C. G., Munroe, M., et al. (1974) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)90872-0 · Cited by 158 · see citing works
Nuclear resonance in flowing liquids
Suryan, G. (1951) · Proceedings of the Indian Academy of Sciences - Section A · doi:10.1007/bf03172192 · Cited by 141 · see citing works
Arpino, P., Dawkins, B. G., & McLafferty, F. W. (1974) · Journal of Chromatographic Science · doi:10.1093/chromsci/12.10.574 · Cited by 101 · see citing works
Jones, D. W., & CHILD, T. F. (1976) · Advances in magnetic and optical resonance · doi:10.1016/b978-0-12-025508-5.50008-6 · Cited by 52 · see citing works
Nuclear Magnetic Resonance in Flowing Fluids
Hirschel, L. R., & Libelo, L. F. (1961) · Journal of Applied Physics · doi:10.1063/1.1736247 · Cited by 18 · see citing works
Flow method in high-resolution nuclear magnetic resonance
Asahi, Y. (1972) · Talanta · doi:10.1016/0039-9140(72)80118-8 · Cited by 14 · see citing works
A flow probe for nuclear magnetic resonance spectroscopy
McIvor, M. C. (1969) · Journal of Physics E Scientific Instruments · doi:10.1088/0022-3735/2/3/421 · Cited by 13 · see citing works
NMR Signal Dependence on Fluid Velocity
Hirschel, L. R., & Libelo, L. F. (1962) · Journal of Applied Physics · doi:10.1063/1.1728857 · Cited by 9 · see citing works
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Hyphenated NMR methods in natural products research, part 1: Direct hyphenation
Jaroszewski, J. W. (2005) · Planta Medica · doi:10.1055/s-2005-871298 · Cited by 104 · see citing works
Vitale, G. A., Geibel, C., Minda, V., Wang, M., Aron, A. T., & Petras, D. (2024) · Natural Product Reports · doi:10.1039/d3np00050h · Cited by 66 · see citing works
- Authors
- Bayer, E., Albert, K., Nieder, M., Grom, E., & Keller, T.
- Affiliations
- University of Tübingen (DE)
- Venue
- Journal of Chromatography A
- Publisher
- Elsevier BV
- Published
- 1979-12
- Volume
- 186
- Pages
- 497-507
- ISSN
- 0021-9673 (ISSN-L)
- OpenAlex
- W2084200059
- Cited by
- 138
- References
- 9
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 5 · 2013: 7 · 2012: 4
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Chromatography A (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Physical Sciences › Chemistry › Spectroscopy › Advanced NMR Techniques and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Keywords
- universal detector, compound classification, unknown compound identification, HPLC separation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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