Exercise-induced complete heart block in a patient with chronic bifascicular block
Abstract
Heart block induced by exercise or associated with symptomatic, chronic bifascicular block can progress to high-grade atrioventricular (AV) block and sudden death. The authors describe a case of exercise-induced AV block in a patient with chronic bifascicular block. Thirty seconds of ventricular asystole were observed during exercise treadmill testing. Myocardial ischemia was ruled out, and the cause was determined to be distal AV nodal block. The pathophysiology, diagnosis, and treatment of distal AV nodal block are reviewed. The role of exercise treadmill testing and electrophysiologic studies in distal AV block are outlined in a diagnostic and therapeutic strategy.
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Tachycardia-related exercise-induced second- and third-degree AV block predicts progression to permanent AV block.
“and predicts progression to permanent AV block. 254,255”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [254]
In tachycardia-related exercise-induced AV block, a resting ECG frequently shows intraventricular conduction abnormalities, but cases with a normal resting ECG have also been described.
“A resting ECG frequently shows intraventricular conduction abnormalities, 253,254 but cases with a normal resting ECG have also been described. 256,257”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [254]
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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy
Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab364 · Cited by 2,019 · see citing works
2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya, A., de Lange, F. J., Deharo, J.-C., Elliott, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy037 · Cited by 1,951 · see citing works
- Authors
- Byrne, J. M., Marais, H. J., & Cheek, G. A.
- Affiliations
- Loma Linda University (US)
- Corresponding author
- Byrne, John M.
- Venue
- Journal of Electrocardiology
- Publisher
- Elsevier BV
- Published
- 1994-10
- Volume
- 27
- Issue
- 4
- Pages
- 339-342
- ISSN
- 0022-0736 (ISSN-L)
- OpenAlex
- W2025709902
- Cited by
- 28
- References
- 11
- Citations by year
- 2026: 1 · 2024: 2 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 2 · 2013: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Electrocardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Keywords
- complete heart block, bifascicular block, atrioventricular block, ventricular asystole, treadmill exercise testing, electrophysiological study, sudden cardiac death, pathophysiology
- MeSH terms
- Aged, Bundle-Branch Block, Chronic Disease, Electrocardiography, Exercise Test, Heart Arrest, Heart Block, Humans, Male, Syncope, Exercise, Exercise Tolerance
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