Cited by 106Cardiac electrophysiology and arrhythmiasCardiac pacing and defibrillation studiesCardiac Arrhythmias and Treatments

Exercise-induced distal atrioventricular block

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Woelfel, Alan K., Simpson, Ross J., Gettes, Leonard S., Foster, James R.·1983·Journal of the American College of Cardiology

Abstract

Three patients with 1:1 atrioventricular (AV) conduction at rest developed fixed 2:1 or 3:1 AV block during treadmill exercise testing. Electrophysiologic study documented block distal to the AV node in all three patients, and suggested that the exercise-induced block occurred because of increased atrial rate and abnormal refractoriness of the His-Purkinje conduction system. The findings in these three patients suggest that high grade AV block appearing during exercise reflects conduction disease of the His-Purkinje system rather than of the AV node, even in the absence of bundle branch block. Patients with this diagnosis should be considered for permanent cardiac pacing.

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Crossref · 10.1016/s0735-1097(83)80288-5

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18 of 18 references verified0 citation errors · 0 not checkable

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  • Tachycardia-related exercise-induced second- and third-degree AV block is located distal to the AV node.

    “Tachycardia-related exerciseinduced second- and third-degree AV block has been shown to be located distal to the AV node 253”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [253]

    The Discussion (page not supplied) reports that three patients developed rate-related 2:1 or 3:1 AV block during exercise and that electrophysiologic testing confirmed a distal site of block. This supports the claim for the high-grade block observed in those patients, but the paper does not establish that all such exercise-induced block is distal to the AV node or document third-degree (complete) block in its cases. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • In tachycardia-related exercise-induced AV block, a resting ECG frequently shows intraventricular conduction abnormalities, but cases with a normal resting ECG have also been described.

    “A resting ECG frequently shows intraventricular conduction abnormalities, 253,254 but cases with a normal resting ECG have also been described. 256,257”

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Cites

Flagged first, then by citations

Research works printed but not linked: 8

  1. I . Gooc h AS . Exercise testmg for detecting change in cardiac rhythm and con duction. Am J Cardiol 1972 ;30:741-6.
  2. Gooch AS. McConnell D. Analysis of transient arrhythmias and con - duction disturbances occurring durin g submaximal exercise testing Prog Cardiovasc Dis 1979;13:293-307 .
  3. Rozanski JJ, Castellanos A. Sheps D, Pozen R, Myerburg RJ. Par- oxy smal second-degree atnovent ricular block induced by exercise Heart Lung 1980;9:887-90 .
  4. Moul opoul os SD , Darsinos J , Sider is DA. Atrioventnc ular block re- sponse to exe rcise and intrave ntricular conduction at rest. Br Heart J 1972;34:998-1 004.
  5. Zepe lh P. Fenici R , Sassava M, Prrrarru MM. Caselli G. Wenckebach second-degree A-V block m top-rankin g athletes: an old problem re- visited. Am Heart J 1980 ;100:281-94.
  6. Oliveros RA . Seaworth J . Weiland FL, et al. lnterrmttent left anten or hemiblock dunng treadmill exe rcise test. Co rrelation With coronary angiogram Chest 1977;72:492-4
  7. Dhmgra RC, Wyndham C, Bauernfeind R, et al. Significance of block distal to the HISbundle induced by atna l pacing in patient s with chronic bifascicular block . Circul ation 1979;60:1455-64.
  8. Kastor JA. Atriove ntnc ular block. N EngI J Med 1975;292:572-4 .

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Authors
Woelfel, A. K., Simpson, R. J., Gettes, L. S., & Foster, J. R.
Affiliations
University of North Carolina at Chapel Hill (US)
Corresponding author
Foster, James R.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
1983-09
Volume
2
Issue
3
Pages
578-581
ISSN
0735-1097 (ISSN-L)
OpenAlex
W2076374966
Cited by
106
References
18
Citations by year
2026: 2 · 2024: 4 · 2023: 3 · 2022: 4 · 2021: 4 · 2020: 3 · 2019: 10 · 2018: 8 · 2017: 9 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 4 · 2012: 1
FWCI
0.73
Type
journal article
Language
en
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
  • Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
  • UNC Libraries
Funders
National Institutes of Health
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords
high-grade atrioventricular block, His-Purkinje system, cardiac conduction disorders, atrial rate, refractoriness, treadmill exercise testing, permanent cardiac pacing, bundle branch block
MeSH terms
Aged, Atrioventricular Node, Electrocardiography, Electrophysiology, Physical Exertion, Heart Block, Heart Conduction System, Humans, Male, Middle Aged

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