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Lipolytic activity of post-heparin plasma in hyperglyceridemia
Open accessAbstract
A standard assay has been developed for the lipolytic activity of post-heparin plasma permitting rate measurements with zero order kinetics over wide ranges of enzymatic activity and concentrations of plasma glycerides. Measurements were made in 60 subjects with hyperglyceridemia, 18 of whom had been further subclassified by dietary studies into either fat-induced or carbohydrate-induced types. Activity in the majority of subjects with hyperglyceridemia, including all of the carbohydrate-induced type, was equal to or greater than that found in normal subjects. Subjects with fat-induced hyperglyceridemia, with one exception, and some of their relatives had abnormally low values. The level of activity in both normal and hyperglyceridemic subjects was uniformly dependent upon prior dietary fat intake.
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Citations
Cited by
A stable, radioactive substrate emulsion for assay of lipoprotein lipase
Nilsson-Ehle, P., & Schotz, M. C. (1976) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41752-3 · Cited by 837
Parks, E. J., & Hellerstein, M. K. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.2.412 · Cited by 530
Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders
Fredrickson, D. S., Levy, R. I., & Lees, R. S. (1967) · New England Journal of Medicine · doi:10.1056/nejm196701192760305 · Cited by 526
Self-citationBrunzell, J. D., Hazzard, W. R., Porte, D., & Bierman, E. L. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107334 · Cited by 484
Kinetics of triglyceride turnover of very low density lipoproteins of human plasma
Reaven, G. M., Hill, D. B., Gross, R. C., & Farquhar, J. W. (1965) · Journal of Clinical Investigation · doi:10.1172/jci105290 · Cited by 221
Metadata
- Authors
- Fredrickson, D. S., Ono, K., & Davis, L. L.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1963-01
- Volume
- 4
- Issue
- 1
- Pages
- 24-33
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2181885523
- Cited by
- 370
- References
- 0
- FWCI
- 69.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Fredrickson, D. S., Ono, K., & Davis, L. L. (1963). Lipolytic activity of post-heparin plasma in hyperglyceridemia. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)40361-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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