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Lipolytic activity of post-heparin plasma in hyperglyceridemia

Open access
Fredrickson, Donald S., Ono, Katsuto, Davis, Louis L.·1963·Journal of Lipid Research

Abstract

A standard assay has been developed for the lipolytic activity of post-heparin plasma permitting rate measurements with zero order kinetics over wide ranges of enzymatic activity and concentrations of plasma glycerides. Measurements were made in 60 subjects with hyperglyceridemia, 18 of whom had been further subclassified by dietary studies into either fat-induced or carbohydrate-induced types. Activity in the majority of subjects with hyperglyceridemia, including all of the carbohydrate-induced type, was equal to or greater than that found in normal subjects. Subjects with fat-induced hyperglyceridemia, with one exception, and some of their relatives had abnormally low values. The level of activity in both normal and hyperglyceridemic subjects was uniformly dependent upon prior dietary fat intake.

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Metadata

Authors
Fredrickson, D. S., Ono, K., & Davis, L. L.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
1963-01
Volume
4
Issue
1
Pages
24-33
ISSN
0022-2275 (ISSN-L)
OpenAlex
W2181885523
Cited by
370
References
0
FWCI
69.39
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Lipolytic activity of post-heparin plasma in hyperglyceridemia. https://app.cochat.ai/papers/10.1016/s0022-2275(20)40361-x
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Fredrickson, D. S., Ono, K., & Davis, L. L. (1963). Lipolytic activity of post-heparin plasma in hyperglyceridemia. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)40361-x

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.