The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
A high-performance liquid chromatographic method for the determination of tocopherol in plasma and cellular elements of the blood.
Open accessAbstract
A rapid sensitive, and reproducible procedure is described for the analysis of alpha-tocopherol in blood cells and plasma using high-performance liquid chromatography and fluorometric detection. The cardinal feature for the increased sensitivity of this high-performance liquid chromatographic procedure is that the fluorometric analysis was carried out at a short excitation wavelength (205 nm) which increased the sensitivity of 20-fold over the usual excitation wavelength of 295 nm. Tocopherol levels can be measured in as little as 50 microliters of plasma and 200 microliters of erythrocytes. The tocopherol contentof plasma, red blood cells, platelets, polymorphonuclear leukocytes, and lymphocytes of normal subjects and subjects ingesting additional quantitites of vitamin E are reported. The values for the white cells are approximately 30 times higher than those of the red blood cells (polymorphonuclear leukocytes 4.47 +/- 0.62 micrograms/10(9), lymphocytes 3.89 +/- 0.85 micrograms/10(9), and erythrocytes 1.40 +/- 0.14 micrograms/10(10) cells). The tocopherol contents of the plasma and all the cellular elements of the blood were increased by oral feeding with vitamin E.
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Citations
Cites
Isolation of mononuclear cells and granulocytes from human blood.
Bøyum, A. (1968) · Scandinavian Journal of Clinical and Laboratory Investigation · Cited by 9,585
Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response
Myers, C. E., McGuire, W. P., Liss, R. H., Ifrim, I., Grotzinger, K., & Young, R. C. (1977) · Science · doi:10.1126/science.877547 · Cited by 1,111
RELATIONSHIP BETWEEN TOCOPHEROL AND SERUM LIPID LEVELS FOR DETERMINATION OF NUTRITIONAL ADEQUACY*
Horwitt, M. K., Harvey, C. C., Dahm, C. H., & Searcy, M. T. (1972) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1972.tb27878.x · Cited by 504
Sensitive fluorometric method for tissue tocopherol analysis
Taylor, S. L., Lamden, M. P., & Tappel, A. L. (1976) · Lipids · doi:10.1007/bf02532898 · Cited by 356
Vitamin E. An inhibitor of the platelet release reaction.
Steiner, M., & Anastasi, J. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108331 · Cited by 209
The transport of α-tocopherol and β-carotene in human blood
Bjornson, L. K., Kayden, H. J., Miller, E., & Moshell, A. N. (1976) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34917-8 · Cited by 163
Self-citationBjornson, L., Gniewkowski, C., & Kayden, H. J. (1975) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36749-3 · Cited by 95
Self-citationDistribution of tocopherols in human plasma and red blood cells
Chow, C. K. (1975) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/28.7.756 · Cited by 92
Factors affecting the exchange of tocopherol between red blood cells and plasma
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Serum Vitamin E Determined by Thin-Layer Chromatography
Bieri, J. G., & Prival, E. L. (1965) · Experimental Biology and Medicine · doi:10.3181/00379727-120-30588 · Cited by 72
Cited by
Burton, G. W., Joyce, A., & Ingold, K. U. (1983) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(83)90145-5 · Cited by 802
Regulatory role of vitamin E in the immune system and inflammation
Lewis, E. D., Meydani, S. N., & Wu, D. (2019) · IUBMB Life · doi:10.1002/iub.1976 · Cited by 406
[15] High-performance liquid chromatography methods for vitamin E in tissues
Buttriss, J. L., & Diplock, A. T. (1984) · Methods in Enzymology · doi:10.1016/s0076-6879(84)05018-7 · Cited by 281
Oral α-Tocopherol Supplements Decrease Plasma γ-Tocopherol Levels in Humans
Handelman, G. J., Machlin, L. J., Fitch, K., Weiter, J. J., & Dratz, E. A. (1985) · The Journal of Nutrition · doi:10.1093/jn/115.6.807 · Cited by 260
Kowluru, R. A., & Odenbach, S. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3233 · Cited by 227
Metadata
- Authors
- Hatam, L. J., & Kayden, H. J.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1979-07
- Volume
- 20
- Issue
- 5
- Pages
- 639-645
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2145916067
- Cited by
- 334
- References
- 11
- FWCI
- 5.03
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Hatam, L. J., & Kayden, H. J. (1979). A high-performance liquid chromatographic method for the determination of tocopherol in plasma and cellular elements of the blood. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)40587-5
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
