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Cited by 423

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Cellularity of rat adipose tissue: effects of growth, starvation, and obesity

Open access
Hirsch, Jules, Han, Paul W.·1969·Journal of Lipid Research
DOI 10.1016/s0022-2275(20)42651-3
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Abstract

The size, number, and rate of formation of mature adipocytes were studied in the epididymal pads and retroperitoneal adipose depots of the Sprague-Dawley rat. Early growth of these depots was accompanied by progressive enlargement of adipose cells as well as by increases in number. Beyond the 15th wk of life, the depot grew exclusively by the process of cellular enlargement, with no further change in cell number. Severe starvation during the 6th wk of life followed by normal feeding had no lasting effect on cell size or cell number; prolonged semistarvation beginning in the 15th wk greatly reduced cell size while cell number was unaffected. Likewise, extreme increases in depot size produced by hypothalamic lesions did not change cell number, but only cell size. The concept of a fixed number of mature adipocytes in the adult organism may be of central importance in caloric and metabolic equilibrium.

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Metadata

Authors
Hirsch, J., & Han, P. W.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
1969-01
Volume
10
Issue
1
Pages
77-82
ISSN
0022-2275 (ISSN-L)
DOI
10.1016/s0022-2275(20)42651-3
OpenAlex
W2184684541
Cited by
423
References
11
FWCI
33.85
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Cellularity of rat adipose tissue: effects of growth, starvation, and obesity. https://app.cochat.ai/papers/10.1016/s0022-2275(20)42651-3
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Hirsch, J., & Han, P. W. (1969). Cellularity of rat adipose tissue: effects of growth, starvation, and obesity. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)42651-3

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.