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Behavioral consequences of congenital rubella
Abstract
Psychiatric and behavioral consequences of congenital rubella are reported for 243 children studies during the preschool period, and for 205 of these who were re-examined at ages 8 to 9. At preschool 37% were retarded, with the skew toward severe and profound; 15% had reactive behavior disorder and 7% had autism. At school age retardation diminished to 25%, but neurotic problems and behavioral pathology due to neurologic damage both increased. There were two remissions and three new instances of autism.
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“The study reported 18 children with some degree of autism, implying an incidence of 741 cases per 10 000 among the population of CRS children”
From The Role of the Immune System in Autism Spectrum Disorder (2017) · cites this paper as Chess, 1978
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Metadata
- Authors
- Chess, S., Fernandez, P., & Korn, S.
- Corresponding author
- Chess, Stella
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 1978-10
- Volume
- 93
- Issue
- 4
- Pages
- 699-703
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2011496335
- Cited by
- 223
- References
- 22
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 8 · 2022: 4 · 2021: 7 · 2020: 6 · 2019: 9 · 2018: 5 · 2017: 7 · 2016: 7 · 2015: 12 · 2014: 11 · 2013: 13 · 2012: 12
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- congenital rubella syndrome, behavioral effects, intellectual disability, autism spectrum disorder, neurobehavioral sequelae, neurologic damage, preschool children, elementary school students, neuropsychiatric outcomes
- MeSH terms
- Autistic Disorder, Child, Child Behavior Disorders, Child Reactive Disorders, Child, Preschool, Humans, Intellectual Disability, Rubella
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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