The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Prenatal exposure to cigarette smoking is associated with a decrease in arousal in infants
Abstract
Objective Sudden infant death syndrome has been related to both exposure to prenatal cigarette smoke and impaired arousability from sleep. We evaluated whether healthy infants born to mothers who smoked during pregnancy had higher auditory arousal thresholds than those born to mothers who did not smoke and whether the effects of smoking occurred before birth. Study design Twenty-six newborns were studied with polygraphic recordings for 1 night: 13 were born to mothers who did not smoke, and 13 were born to mothers who smoked (>9 cigarettes per day). Other infants with a median postnatal age of 12 weeks were also studied, 21 born to nonsmoking mothers and 21 born to smoking mothers. White noise of increasing intensity was administered during rapid eye movement sleep to evaluate arousal and awakening thresholds. Results More intense auditory stimuli were needed to induce arousals in newborns (P =.002) and infants (P =. 044) of smokers than in infants of nonsmokers. Behavioral awakening occurred significantly less frequently in the newborns of smokers (P =.002) than of nonsmokers. Conclusions Newborns and infants born to smoking mothers had higher arousal thresholds to auditory challenges than those born to nonsmoking mothers. The impact of exposure to cigarette smoke occurred before birth.
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“Maternal smoking and smokeless tobacco use during pregnancy are associated with increased risk of neonatal apnea, while maternal smoking is also associated with a decreased arousal response.”
From Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products (2017) · cites this paper as [113]
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“Maternal smoking and smokeless tobacco use during pregnancy are associated with increased risk of neonatal apnea”
From Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products (2017) · cites this paper as [113]
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“while maternal smoking is also associated with a decreased arousal response.”
From Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products (2017) · cites this paper as [113]
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Cites
Hobson, J. A. (1972) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(72)90252-0 · Cited by 480
Smoking and the Sudden Infant Death Syndrome
Mitchell, E. A., Ford, R. P. K., Stewart, A., Taylor, B. J., Becroft, D. M. O., Thompson, J., Scragg, R. K. R., Hassall, I. B., Barry, D. M., Allen, E. M., et al. (1993) · PEDIATRICS · doi:10.1542/peds.91.5.893 · Cited by 284
Assessment of exposure to environmental tobacco smoke
Jaakkola, M., & Jaakkola, J. J. K. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10102384 · Cited by 266
Scher, M. S., Richardson, G. A., Coble, P. A., Day, N. L., & Stoffer, D. S. (1988) · Pediatric Research · doi:10.1203/00006450-198807000-00023 · Cited by 222
Arousal pattern following central and obstructive breathing abnormalities in infants and children
McNamara, F., Issa, F. G., & Sullivan, C. E. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.6.2651 · Cited by 212
Lewis, K., & Bosque, E. M. (1995) · The Journal of Pediatrics · doi:10.1016/s0022-3476(95)70155-9 · Cited by 205
Epidemiology of the Sudden Infant Death Syndrome: Maternal, Neonatal, and Postneonatal Risk Factors
Hoffman, H. J., & Hillman, L. S. (1992) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30427-5 · Cited by 195
Slotkin, T. A., Lappi, S. E., McCook, E. C., Lorber, B. A., & Seidler, F. J. (1995) · Brain Research Bulletin · doi:10.1016/0361-9230(95)00073-n · Cited by 191
Prone or Supine Body Position and Sleep Characteristics in Infants
Kahn, A., Groswasser, J., Sottiaux, M., Rebuffat, E., Franco, P., & Dramaix, M. (1993) · PEDIATRICS · doi:10.1542/peds.91.6.1112 · Cited by 139
Self-citationEarly developmental changes in [3H]nicotine binding in the human brainstem
Kinney, H. C., O'Donnell, T. J., Kriger, P., & White, W. F. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90326-b · Cited by 122
Ontogenetic variations in auditory arousal threshold during sleep
Busby, K., Mercier, L., & Pivik, R. T. (1994) · Psychophysiology · doi:10.1111/j.1469-8986.1994.tb01038.x · Cited by 121
Prenatal exposure to cigarettes in infants with obstructive sleep apneas
Kahn, A., Groswasser, J., Sottiaux, M., Kelmanson, I., Franco, P., Rebuffat, E., Dramaix, M., & Wayenberg, J. L. (1994) · PEDIATRICS · doi:10.1542/peds.93.5.778 · Cited by 117
Self-citationDecreased Cardiac Responses to Auditory Stimulation During Prone Sleep
Franco, P., Groswasser, J., Sottiaux, M., Broadfield, E., & Kahn, A. (1996) · PEDIATRICS · doi:10.1542/peds.97.2.174 · Cited by 107
Self-citationThe behaviour of infants whose mothers smoke in pregnancy
Saxton, D. W. (1978) · Early Human Development · doi:10.1016/0378-3782(78)90063-4 · Cited by 102
Exposure of the Fetus, Neonate, and Nursed Infant to Nicotine and Cotinine from Maternal Smoking
Luck, W., & Nau, H. (1984) · New England Journal of Medicine · doi:10.1056/nejm198409063111014 · Cited by 93
Phenothiazine-Induced Sleep Apneas in Normal Infants
Kahn, A., Hasaerts, D., & Blum, D. (1985) · PEDIATRICS · doi:10.1542/peds.75.5.844 · Cited by 78
Self-citationNicotine Attenuates the Ventilatory Response to Hypoxia in the Developing Lamb
Milerad, J., Larsson, H., Lin, J., & Sundell, H. W. (1995) · Pediatric Research · doi:10.1203/00006450-199505000-00017 · Cited by 68
Ecology of passive smoking by young infants
Greenberg, R. A., Bauman, K. E., Glover, L. H., Strecher, V. J., Kleinbaum, D. G., Haley, N. J., Stedman, H. C., Fowler, M. G., & Loda, F. A. (1989) · The Journal of Pediatrics · doi:10.1016/s0022-3476(89)80135-0 · Cited by 58
Mechanism of the suddent infant death syndrome?
NEWMAN, N. M., Trinder, J. A., PHILLIPS, K., JORDAN, K., & CRUICKSHANK, J. (1989) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.1989.tb01454.x · Cited by 55
The Hazards of Passive -- And Active -- Smoking
Boyle, P. (1993) · New England Journal of Medicine · doi:10.1056/nejm199306103282311 · Cited by 47
Fewell, J. E., Williams, B. J., Szabo, J. S., & Taylor, B. J. (1988) · Pediatric Research · doi:10.1203/00006450-198802000-00013 · Cited by 41
Thomas, D., Poole, K., McArdle, E. K., Goodenough, P. C., Thompson, J., Beardsmore, C., & Simpson, H. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09050932 · Cited by 36
Research works printed but not linked: 1
- Newman, 1989, Arousal deficit: Mechanisms of the sudden infant death syndrome?, Aust Paediatr J, 25, 196
Cited by
Sorted by citations
Moon, R. Y., & Task Force on Sudden Infant Death Syndrome (2011) · PEDIATRICS · doi:10.1542/peds.2011-2284 · Cited by 731
Moon, R. Y., Horne, R. S. C., & Hauck, F. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61662-6 · Cited by 586
Moon, R. Y., TASK FORCE ON SUDDEN INFANT DEATH SYNDROME, Darnall, R. A., Feldman-Winter, L., Goodstein, M. H., & Hauck, F. R. (2016) · Pediatrics · doi:10.1542/peds.2016-2940 · Cited by 583
Perinatal complications associated with maternal tobacco use
Andres, R. L., & Day, M.-C. (2000) · Seminars in Neonatology · doi:10.1053/siny.2000.0025 · Cited by 524
The Visual Scoring of Sleep and Arousal in Infants and Children
Grigg-Damberger, M., Gozal, D., Marcus, C. L., Quan, S. F., Rosen, C. L., Chervin, R. D., Wise, M., Picchietti, D. L., Sheldon, S. H., & Iber, C. (2007) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.26819 · Cited by 361
Metadata
- Authors
- Franco, P., Groswasser, J., Hassid, S., Lanquart, J. P., Scaillet, S., & Kahn, A.
- Affiliations
- Erasmus Hospital (BE)
- Université Libre de Bruxelles (BE)
- ORCID
- Franco, Patricia
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 1999-07
- Volume
- 135
- Issue
- 1
- Pages
- 34-38
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2084739803
- Cited by
- 146
- References
- 22
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2022: 1 · 2020: 2 · 2018: 4 · 2017: 3 · 2016: 7 · 2015: 4 · 2014: 1 · 2013: 5 · 2012: 5
- FWCI
- 11.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Keywords
- smoking during pregnancy, infant arousal, sudden infant death syndrome, neonates, infants, REM sleep
- MeSH terms
- Arousal, Auditory Threshold, Female, Humans, Infant, Infant, Newborn, Male, Pregnancy, Prenatal Exposure Delayed Effects, Tobacco Smoke Pollution, Case-Control Studies, Polysomnography, Statistics, Nonparametric
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