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Cited by 235

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A FLUOROMETRIC PROCEDURE FOR THE MEASUREMENT OF TRYPTAMINE IN TISSUES

Hess, Sidney M., Udenfriend, Sidney·1959·The Journal of Pharmacology and Experimental Therapeutics

Abstract

A fluorometric method sufficiently sensitive to determine 0.1 to 5 µg of tryptamine in body fluids and tissues is described. The method involves an extraction with benzene, cyclization with formaldehyde to produce tetrahydronorharman followed by a dehydrogenation to form the highly fluorescent product norharman. By omitting the extraction, the procedure can be applied to measure tryptophan in fingertip blood.

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Metadata

Authors
Hess, S. M., & Udenfriend, S.
Venue
The Journal of Pharmacology and Experimental Therapeutics
Publisher
Elsevier BV
Published
1959-11
Volume
127
Issue
3
Pages
175-177
ISSN
0022-3565 (ISSN-L)
OpenAlex
W2254503714
Cited by
235
References
0
FWCI
9.53
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A FLUOROMETRIC PROCEDURE FOR THE MEASUREMENT OF TRYPTAMINE IN TISSUES. https://app.cochat.ai/papers/10.1016/s0022-3565(25)25679-8
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Hess, S. M., & Udenfriend, S. (1959). A FLUOROMETRIC PROCEDURE FOR THE MEASUREMENT OF TRYPTAMINE IN TISSUES. The Journal of Pharmacology and Experimental Therapeutics. https://doi.org/10.1016/s0022-3565(25)25679-8

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.