The DOI matches its Crossref record; 111 of the 113 references it cites were found in a registry or an index.
Vision and cognition in Alzheimer’s disease
Abstract
Alzheimer's disease (AD) is known to affect visual pathways, but potential concomitant effects on vision and cognitive performance are not well understood. We studied 43 individuals with AD of mild severity and 22 individuals without dementia on a battery of tests designed to measure multiple aspects of basic and higher-order visual perception and cognition. All subjects performed on the same visual and cognitive test batteries. The results showed no differences between groups on tests of static visual acuity, stereoacuity, dynamic visual acuity or motion direction discrimination. However, individuals with AD performed significantly worse on tests of static spatial contrast sensitivity, visual attention, shape-from-motion, color, visuospatial construction and visual memory. Correlation analyses showed strong relationships between visual and cognitive scores. The findings show that AD affects several aspects of vision and are compatible with the hypothesis that visual dysfunction in AD may contribute to performance decrements in other cognitive domains. The pattern of involvement indicates that AD affects multiple visual neural pathways and regions. It is possible that better understanding of vision-related dysfunction could aid diagnosis and interventions to improve functional capacity in patients with dementia.
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“visual attention and control of visual short-term memory decline as a result of neurodegenerative processes that occur with ageing, MCI, and AD [51,52,53]”
From Designing ICTs for Users with Mild Cognitive Impairment: A Usability Study (2020) · cites this paper as [53]
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Cites
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At the interface of sensory and motor dysfunctions and Alzheimer’s disease.
Albers, M. W., Gilmore, G. C., Kaye, J., Murphy, C., Wingfield, A., Bennett, D. A., Boxer, A. L., Buchman, A. S., Cruickshanks, K. J., Devanand, D. P., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.04.514 · Cited by 589
Focal Decline of Cortical Thickness in Alzheimer's Disease Identified by Computational Neuroanatomy
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Self-citation
Metadata
- Authors
- Rizzo, M.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Rizzo, M
- Venue
- Neuropsychologia
- Publisher
- Elsevier BV
- Published
- 2000-07
- Volume
- 38
- Issue
- 8
- Pages
- 1157-1169
- ISSN
- 0028-3932 (ISSN-L)
- OpenAlex
- W2118867177
- Cited by
- 308
- References
- 113
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 7 · 2023: 13 · 2022: 20 · 2021: 16 · 2020: 18 · 2019: 7 · 2018: 12 · 2017: 12 · 2016: 19 · 2015: 12 · 2014: 11 · 2013: 14 · 2012: 13
- FWCI
- 4.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychologia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Centers for Disease Control and Prevention
- U.S. Public Health Service (R49/CCR710136)
- National Institute of Neurological Disorders and Stroke (P0 NS 19632)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- Alzheimer's disease, visual perception, visual dysfunction, spatial contrast sensitivity, visual attention, shape from motion, color vision, visuospatial construction, visual memory, visual pathway, dementia, cognitive decline
- MeSH terms
- Aged, Aged, 80 and over, Alzheimer Disease, Attention, Brain Mapping, Female, Humans, Male, Neuropsychological Tests, Perceptual Disorders, Vision Disorders, Vision Tests, Visual Cortex, Visual Pathways, Visual Perception
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