The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The Pharmacology of Ryanodine and Related Compounds
Abstract
The goal of this review has been to describe the current state of the pharmacology of ryanodine and related compounds relative to the vertebrate RyRs. Resolution of questions concerning the molecular properties of RyR channel function and the contributions made by the RyR isoforms to cellular signaling in a variety of tissues will require the production of new pharmacological agents directed against these proteins. Novel naturally occurring ryanodine congeners have been identified, and significant advances have been made in developing chemical approaches that permit the structure of ryanodine to be derivatized in selective ways. Moreover, several of these changes have yielded compounds that differ in their binding affinities and in their abilities to modify the properties of the RyR channels. These advances give substance to the possibility of designing the required pharmacological agents based on rational design changes of the structure ryanodine.
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Cramer, R. D., Patterson, D. E., & Bunce, J. D. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00226a005 · Cited by 3,931
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
Takeshima, H., Nishimura, S., Matsumoto, T., Ishida, H., Kangawa, K., Minamino, N., Matsuo, H., Ueda, M., Hanaoka, M., Hirose, T., et al. (1989) · Nature · doi:10.1038/339439a0 · Cited by 1,146
Naturally Occurring Insecticides
Jacobson, M., Crosby, D. G., & FORGASH, A. J. (1972) · Soil Science · doi:10.1097/00010694-197205000-00015 · Cited by 543
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Verkhratsky, A. (2005) · Physiological Reviews · doi:10.1152/physrev.00004.2004 · Cited by 709
Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging
Umanskaya, A., Santulli, G., Xie, W., Andersson, D. C., Reiken, S. R., & Marks, A. R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1412754111 · Cited by 157
Pest Control Agents from Natural Products
Ujváry, I. (2010) · Hayes' Handbook of Pesticide Toxicology · doi:10.1016/b978-0-12-374367-1.00003-3 · Cited by 81
Metadata
- Authors
- Sutko, J. L., Airey, J. A., Welch, W., & Ruest, L.
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 1997-03
- Volume
- 49
- Issue
- 1
- Pages
- 53-98
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W2116990945
- Cited by
- 274
- References
- 3
- FWCI
- 3.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sutko, J. L., Airey, J. A., Welch, W., & Ruest, L. (1997). The Pharmacology of Ryanodine and Related Compounds. Pharmacological Reviews. https://doi.org/10.1016/s0031-6997(24)01313-9
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
