The DOI matches its Crossref record.
Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Both THC and CBD are predominantly metabolized, by the liver, through the action of the cytochrome P450 system.104,105”
From Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions (2024) · cites this paper as [105]
In the citing paper
“however, it should be pointed out that previous investigations have not been able to confirm whether there is a direct relationship between plasma levels of cannabinoids, in particular CBD, and their clinical effects (Agurell et al, 1986).”
From Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients (2011) · cites this paper as Agurell et al, 1986
Citations
Cited by
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Items 401–409 of 409
Igwe, J., & Alaribe, U. (2024) · Journal of Cannabis Research · doi:10.1186/s42238-024-00228-w
“…upon the chronicity of use, the slow release of Δ9-THC and other cannabinoids from tissues and subsequent metabolism results in a long elimination half-life (Agurell et al. 1986; Huestis 2007; Basis for the Recommendation to Reschedule Mar-ijuana into Schedule III of the Controlled Substances Act.”
BackgroundMeta-Analysis of Herbal Cannabis Therapy for Chronic Pain
Seneca, M. (2014) · University of North Florida Digital Commons (University of North Florida)
Stražanac, D., Miloš, S., Jurković, M., et al. (2025) · Food Risk Assess Europe · doi:10.2903/fr.efsa.2025.fr-0078
Jurković, M., Bašić, S., & Knežević, D. (2025) · Food Risk Assess Europe · doi:10.2903/fr.efsa.2025.fr-0079
The Endocannabinoid System and Medicinal Cannabis
O’Brien, K., & Bosak, C. (2025) · Springer eBooks · doi:10.1007/978-3-032-01737-6_2
Amann, F., Hefner, G., Cremer-Schaeffer, P., Gründer, G., Häuser, W., Hart, X. M., Petzke, F. W., Zernig, G., & Havemann‐Reinecke, U. (2026) · Pharmacopsychiatry · doi:10.1055/a-2853-4984 · Cited by 1
Mitochondrial dysfunction and autophagy activation underlie NK cell impairment induced by Cannabis
Bolduc, A., Tremblay, T., Almutairi, M., Semlali, A., & Loubaki, L. (2026) · PLoS ONE · doi:10.1371/journal.pone.0350750
“Similarly, one minute after intravenous administration of 5 mg of THC (9.55 x 10¹ ⁸ molecules), plasma concentrations reached 4.28 x 10¹ ⁴ molecules/mL, meaning only 22% [41].”
InfluentialAlves, G. L. F., Gonçalves, D. D. F., de Oliveira, P. C., Tavares, D. D. Q., Santos, G. C., & Oliveira, C. R. (2026) · Pará Research Medical Journal · doi:10.5327/prmj.944
Cannabinoids for the control of experimental multiple sclerosis
Pryce, G. (2010) · OpenGrey (Institut de l'Information Scientifique et Technique)
Metadata
- Authors
- Agurell, S., Halldin, M., Lindgren, J. E., Ohlsson, A., Widman, M., Gillespie, H., & Hollister, L.
- ORCID
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 1986-03
- Volume
- 38
- Issue
- 1
- Pages
- 21-43
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W2107684761
- Cited by
- 406
- References
- 0
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 10 · 2023: 7 · 2022: 5 · 2021: 8 · 2020: 45 · 2019: 17 · 2018: 12 · 2017: 11 · 2016: 21 · 2015: 14 · 2014: 14 · 2013: 8 · 2012: 10
- FWCI
- 7.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacological Reviews (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Keywords
- delta-1-tetrahydrocannabinol, cannabinoids, pharmacokinetics, drug metabolism, human metabolism
- MeSH terms
- Animals, Biotransformation, Cannabidiol, Cannabinoids, Drug Tolerance, Feces, Humans, Kinetics, Dronabinol, Tissue Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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