Long-term results after surgery for acute mesenteric ischemia
Abstract
Background Acute mesenteric ischemia is associated with high mortality rates, and little is known about the long-term prognosis of patients after initially successful surgical intervention.Methods Ninety patients were treated by vascular reconstruction or bowel resection, or both, between 1972 and 1993. The overall mortality was 66%. The outcomes and rehabilitational statuses of those 31 patients who were discharged from the hospital were analyzed retrospectively. Anticoagulation consisted of vitamin K antagonists in patients with venous thrombosis and arterial embolism or inhibition of thrombocyte aggregation in patients with arterial thrombosis and nonocclusive mesenteric ischemia.Results In 31 patients discharged from the hospital venous thrombosis, arterial embolism, arterial thrombosis, and nonocclusive disease occurred in 19, 5, 5, and 2 patients, respectively. The 2- and 5-year survival rates were 70% and 50% and mainly related to cardiovascular comorbidity and malignant disease. Only one patient died after a recurrent attack of arterial mesenteric thrombosis. Twenty percent of the patients suffered from chronic short bowel syndrome after extensive bowel resection, but none required permanent parenteral nutrition.Conclusions Under appropriate anticoagulation there is a remarkably low risk of recurrent mesenteric ischemia. The impaired life expectancy of long-surviving patients is mainly due to cardiovascular comorbidity and malignancies.
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Klempnauer et al. found in a long-term study that patients who survive extensive bowel resection have 2-year and 5-year survival rates of 70% and 50% respectively.
“Klempnauer et al[127] did a long-term study on those patients and found that their 2-year and 5-year survival rates were 70% and 50% respectively[127].”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [127]
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- Authors
- Klempnauer, J., Grothues, F., Bektas, H., & Pichlmayr, R.
- Affiliations
- Medizinische Hochschule Hannover (DE)
- Venue
- Surgery
- Publisher
- Elsevier BV
- Published
- 1997-03
- Volume
- 121
- Issue
- 3
- Pages
- 239-243
- ISSN
- 0039-6060 (ISSN-L)
- OpenAlex
- W2000167599
- Cited by
- 119
- References
- 15
- Citations by year
- 2026: 2 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 6 · 2017: 4 · 2016: 5 · 2015: 4 · 2014: 5 · 2013: 6 · 2012: 7
- FWCI
- 3.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Emergency Medicine › Appendicitis Diagnosis and Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Thrombus and Embolism
- Keywords
- acute mesenteric ischemia, long-term prognosis, vascular reconstruction, bowel resection, anticoagulation, vitamin K antagonists, venous thrombosis, arterial embolism, arterial thrombosis, nonocclusive mesenteric ischemia, survival, cardiovascular comorbidity, cancer
- MeSH terms
- Acute Disease, Anticoagulants, Body Weight, Cause of Death, Embolism, Follow-Up Studies, Humans, Prognosis, Recurrence, Splanchnic Circulation, Time Factors, Survival Analysis, Colitis, Ischemic
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