The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Lymphocyte Trafficking and Regional Immunity
Open accessAbstract
This chapter discusses the lymphocyte trafficking and regional immunity. The chapter discusses the present understanding of tissue-selective lymphocyte trafficking, focusing in particular on the gut and its associated lymphoid tissues. The sophisticated cellular, developmental, and molecular mechanisms involved are discussed in the chapter with emphasis on the importance of these mechanisms for the understanding and manipulation of regional immune responses in the gastrointestinal tract. Lymphocytes are migratory cells, trafficking from their sites of origin in the bone marrow and thymus and homing to and recirculating through specialized lymphoid and extra lymphoid tissues in the periphery. Like all leukocytes, lymphocytes develop with characteristic trafficking properties. A central tenet of current thinking in the field is that this tissue-specific targeting of antigen-reactive populations must increase the efficiency of immune surveillance by circulating memory cells as well as enhancing local immune responses. From the perspective of regional physiology and pathology, selective trafficking may also provide a mechanism for segregating the specialized immune response modalities characteristic of intestinal versus systemic immune responses.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lymphocyte Homing and Homeostasis
Butcher, E. C., & Picker, L. J. (1996) · Science · doi:10.1126/science.272.5258.60 · Cited by 2,846
Self-citationAdhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin
Cepek, K. L., Shaw, S. K., Parker, C. M., Russell, G. J., Morrow, J. S., Rimm, D. L., & Brenner, M. B. (1994) · Nature · doi:10.1038/372190a0 · Cited by 1,178
Cited by
Involvement of chemokine receptors in breast cancer metastasis
Müller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N., et al. (2001) · Nature · doi:10.1038/35065016 · Cited by 5,340
Retinoic acid imprints gut-homing specificity on T cells
Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C., & Song, S.-Y. (2004) · Immunity · doi:10.1016/j.immuni.2004.08.011 · Cited by 1,541
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
Kanzler, H., Barrat, F. J., Hessel, E. M., & Coffman, R. L. (2007) · Nature Medicine · doi:10.1038/nm1589 · Cited by 869
The Vast Majority of CLA+ T Cells Are Resident in Normal Skin
Clark, R. A., Chong, B., Mirchandani, N., Brinster, N. K., Yamanaka, K.-I., Dowgiert, R. K., & Kupper, T. S. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4431 · Cited by 796
Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation
Buckley, C. D., Pilling, D., Lord, J. M., Akbar, A. N., Scheel-Toellner, D., & Salmon, M. (2001) · Trends in Immunology · doi:10.1016/s1471-4906(01)01863-4 · Cited by 796
Hepatic T cells and liver tolerance
Crispe, I. N. (2003) · Nature Reviews Immunology · doi:10.1038/nri981 · Cited by 661
Watanabe, R., Gehad, A., Yang, C., Scott, L. L., Teague, J. E., Schlapbach, C., Elco, C. P., Huang, V., Matos, T. R., Kupper, T. S., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.3010302 · Cited by 569
Intracellular signalling controlling integrin activation in lymphocytes
Kinashi, T. (2005) · Nature Reviews Immunology · doi:10.1038/nri1646 · Cited by 477
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
Stefanová, I., Dorfman, J. R., & Germain, R. N. (2002) · Nature · doi:10.1038/nature01146 · Cited by 389
(2003) · PubMed · Cited by 355
CCR7 Expression and Memory T Cell Diversity in Humans
Campbell, J. J., Murphy, K. E., Kunkel, E. J., Brightling, C. E., Soler, D., Shen, Z., Boisvert, J., Greenberg, H. B., Vierra, M. A., Goodman, S. B., et al. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.2.877 · Cited by 335
Self-citationChemokines in the systemic organization of immunity
Campbell, D. J., Kim, C. H., & Butcher, E. C. (2003) · Immunological Reviews · doi:10.1034/j.1600-065x.2003.00067.x · Cited by 330
Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention
Gorfu, G., Rivera-Nieves, J., & Ley, K. (2009) · Current Molecular Medicine · doi:10.2174/156652409789105525 · Cited by 292
Piccio, L., Rossi, B., Scarpini, E., Laudanna, C., Giagulli, C., Issekutz, A. C., Vestweber, D., Butcher, E. C., & Constantin, G. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1940 · Cited by 245
Self-citationLymphocyte homing to the gut: attraction, adhesion, and commitment
Salmi, M., & Jalkanen, S. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00285.x · Cited by 103
Aberrant disgust responses and immune reactivity in cocaine-dependent men.
Ersche, K. D., Hagan, C. C., Smith, D. G., Abbott, S., Jones, P. S., Apergis-Schoute, A. M., & Döffinger, R. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.08.004 · Cited by 52
Functional heterogeneity of CD4+ T cells in liver inflammation
Muscate, F., Woestemeier, A., & Gagliani, N. (2021) · Seminars in Immunopathology · doi:10.1007/s00281-021-00881-w · Cited by 32
Die Regulation des Immunsystems und immunprivilegierte Organe
Haase, H., Kruse, A., & Rink, L. (2015) · Immunologie für Einsteiger · doi:10.1007/978-3-662-44843-4_7 · Cited by 1
Metadata
- Venue
- Advances in Immunology
- Publisher
- Elsevier
- Published
- 1999
- Volume
- 72
- Pages
- 209-253
- ISSN
- 0065-2776 (ISSN-L)
- OpenAlex
- W1535141082
- Cited by
- 674
- References
- 2
- FWCI
- 37.27
- Type
- book chapter
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
