The DOI matches its Crossref record, with a small difference in title or year; 134 of the 137 references it cites were found in a registry or an index.
Early-life handling stimulation and environmental enrichment
Abstract
Neonatal (early) handling (EH) and environmental enrichment (EE) of laboratory rodents have been the two most commonly used methods of providing supplementary environmental stimulation in order to study behavioral and neurobiological plasticity. A large body of research has been generated since the 1950s, unequivocally showing that both treatments induce profound and long-lasting behavioral and neural consequences while also inducing plastic brain effects and being "protective" against some age-related deficits. The present work is aimed at reviewing the main neurobehavioral effects of both manipulations, with the final purpose of comparing them and trying to find out to what extent the effects of both treatments may share (or not) possible neural mechanisms.
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“The findings of Francis et al. (2002) and Bredy et al. (2003) indicate that the effects of enrichment as seen at the behavioral level are not necessarily mirrored in expected changes at the biological level (Fernandez-Teruel et al., 2002).”
From Stress and the development of self-regulation in context (2010) · cites this paper as Fernandez-Teruel et al., 2002
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Cites
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Sorted by citations
Benaroya‐Milshtein, N., Hollander, N., Apter, A., Kukulansky, T., Raz, N., Wilf, A., Yaniv, I., & Pick, C. G. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03587.x · Cited by 439
Stress and the development of self-regulation in context
Blair, C. (2010) · Child Development Perspectives · doi:10.1111/j.1750-8606.2010.00145.x · Cited by 379
“The findings of Francis et al. (2002) and Bredy et al. (2003) indicate that the effects of enrichment as seen at the behavioral level are not necessarily mirrored in expected changes at the biological level (Fernandez-Teruel et al., 2002).”
BackgroundLaviola, G., Hannan, A. J., Macrì, S., Solinas, M., & Jaber, M. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.05.001 · Cited by 300
Environmental enrichment induces optimistic cognitive bias in rats
Brydges, N. M., Leach, M. C., Nicol, K., Wright, R., & Melissa Bateson, B. (2010) · Animal Behaviour · doi:10.1016/j.anbehav.2010.09.030 · Cited by 293
Fox, C., Merali, Z., & Harrison, C. R. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.016 · Cited by 283
Metadata
- Authors
- Fernández-Teruel, A., Giménez-Llort, L., Escorihuela, R. M., Gil, L., Aguilar, R., Steimer, T., & Tobeña, A.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- Venue
- Pharmacology Biochemistry and Behavior
- Publisher
- Elsevier BV
- Published
- 2002-08
- Volume
- 73
- Issue
- 1
- Pages
- 233-245
- ISSN
- 0091-3057 (ISSN-L)
- OpenAlex
- W80710638
- Cited by
- 171
- References
- 137
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 6 · 2019: 8 · 2018: 7 · 2017: 8 · 2016: 5 · 2015: 11 · 2014: 8 · 2013: 7 · 2012: 7
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacology Biochemistry and Behavior (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- neonatal handling, environmental enrichment, laboratory rodents, neuroplasticity, behavioral plasticity, neurobehavioral effects, brain development, age-related deficits, neural mechanisms
- MeSH terms
- Animals, Animals, Newborn, Environment, Exploratory Behavior, Handling, Psychological, Learning, Rats
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