The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Cellular Senescence
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“Cell proliferation in settings of insufficient telomerase results in progressive telomere shortening, ultimately leading to replicative senescence as chromosome end-protection is compromised at a subset of short telomeres (Rodier et al., 2005; Sherr and DePinho, 2000).”
From Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice (2010) · cites this paper as Sherr and DePinho, 2000
Citations
Cites
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
The serial cultivation of human diploid cell strains
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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., & Lowe, S. W. (1997) · Cell · doi:10.1016/s0092-8674(00)81902-9 · Cited by 5,218 · cited 1×
“…same panoply of cell cycle regulatory proteins nortemptation has been to link conclusions drawn from mally associated with arresting cells and undergo “prestudies in these different cell systems, equating senes- mature senescence” (Serrano et al., 1997), whereas escence in mouse and human cells.”
BackgroundExtension of Life-Span by Introduction of Telomerase into Normal Human Cells
Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C.-P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., & Wright, W. E. (1998) · Science · doi:10.1126/science.279.5349.349 · Cited by 4,975
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Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
Blasco, M. A., Lee, H.-W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., & Greider, C. W. (1997) · Cell · doi:10.1016/s0092-8674(01)80006-4 · Cited by 2,108
Self-citationTumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19
Kamijo, T., Zindy, F., Roussel, M. F., Quelle, D. E., Downing, J. R., Ashmun, R. A., Grosveld, G., & Sherr, C. J. (1997) · Cell · doi:10.1016/s0092-8674(00)80452-3 · Cited by 1,566
Self-citationMyc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., & Roussel, M. F. (1998) · Genes & Development · doi:10.1101/gad.12.15.2424 · Cited by 1,245
Self-citationKiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., & Klingelhutz, A. J. (1998) · Nature · doi:10.1038/23962 · Cited by 1,206 · cited 1×
“Removing the telomerements TERT reconstitution in the immortalization pro- cess (Kiyono et al., 1998).”
Backgroundp53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2
Karlseder, J., Broccoli, D., Dai, Y., Hardy, S., & de Lange, T. (1999) · Science · doi:10.1126/science.283.5406.1321 · Cited by 1,086
Chin, L., Artandi, S. E., Shen, Q., Tam, A., Lee, S.-L., Gottlieb, G. J., Greider, C. W., & DePinho, R. A. (1999) · Cell · doi:10.1016/s0092-8674(00)80762-x · Cited by 979 · cited 2×
“On the other hand, observations that late-generation mTR null cells mTR null animals, the levels of p53 and p53-responsive with shortened telomeres (Chin et al., 1999) or cells with otherwise disrupted telomere structures (Karlseder et al., 1999) initiate p53-dependent DNA damage responses lend…”
BackgroundSelf-citationDevelopmental and tissue-specific regulation of mouse telomerase and telomere length.
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The two-stage mechanism controlling cellular senescence and immortalization
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Telomeres, Telomerase and Cancer
Greider, C. W., & Blackburn, E. H. (1996) · Scientific American · doi:10.1038/scientificamerican0296-92 · Cited by 314
p16INK4A and p19ARF act in overlapping pathways in cellular immortalization
Carnero, A., Hudson, J. D., Price, C. M., & Beach, D. (2000) · Nature Cell Biology · doi:10.1038/35004020 · Cited by 280
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Extended Culture of Mouse Embryo Cells Without Senescence: Inhibition by Serum
Loo, D. T., Fuquay, J. I., Rawson, C. L., & Barnes, D. W. (1987) · Science · doi:10.1126/science.3494308 · Cited by 219
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Cited by
Sorted by citations
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
The essence of senescence: Figure 1.
Kuilman, T., Michaloglou, C., Mooi, W. J., & Peeper, D. S. (2010) · Genes & Development · doi:10.1101/gad.1971610 · Cited by 2,038
The RB and p53 pathways in cancer
Sherr, C. J., & McCormick, F. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00102-2 · Cited by 1,690
Self-citationGenetics and biology of pancreatic ductal adenocarcinomaPreprint
Hezel, A. F., Kimmelman, A. C., Stanger, B. Z., Bardeesy, N. M., & DePinho, R. A. (2006) · Genes & Development · doi:10.1101/gad.1415606 · Cited by 1,611
Self-citationInk4a/Arf expression is a biomarker of aging
Krishnamurthy, J., Torrice, C., Ramsey, M. R., Kovalev, G. I., Al-Regaiey, K., Su, L., & Sharpless, N. E. (2004) · Journal of Clinical Investigation · doi:10.1172/jci22475 · Cited by 1,486
Metadata
- Authors
- Sherr, C. J., & DePinho, R. A.
- Affiliations
- St. Jude Children's Research Hospital (US)
- Harvard University (US)
- Corresponding author
- Sherr, Charles J
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 102
- Issue
- 4
- Pages
- 407-410
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2324248025
- Cited by
- 745
- References
- 20
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 13 · 2023: 10 · 2022: 13 · 2021: 19 · 2020: 20 · 2019: 16 · 2018: 7 · 2017: 30 · 2016: 17 · 2015: 19 · 2014: 24 · 2013: 19 · 2012: 31
- FWCI
- 36.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Keywords
- cellular senescence, biological aging, human fibroblasts, mouse fibroblasts, culture shock, telomere integrity, cell cycle inhibitors, oncogenic transformation, chromosome stability
- MeSH terms
- Animals, Humans, Mitosis, Models, Biological, Telomere, Cellular Senescence
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