The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice
Abstract
The gene for mouse myelin basic protein (MBP) was mapped to chromosome 18 by hybridization of cloned MBP probes to DNA from hamster-mouse hybrid cell lines, showing it to be linked to the shiverer mutation which causes abnormal CNS myelination. Genomic blotting experiments show that in the mutants five of six exons which constitute the wild-type gene have been deleted. In shiverer brains the steady state level of transcripts that initiate correctly at the 5' end of the remaining exon 1 is reduced 16-fold. These RNAs are not spliced correctly and are not efficiently polyadenylated. It is proposed that the partial deletion of the MBP gene is an important part of the shiverer lesion.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Indeed, diffusion anisotropy is present even when compact myelin is completely absent, although it is significantly reduced (Roach et al., 1985; Watanabe et al., 2010).”
From The role of myelination in measures of white matter integrity: Combination of diffusion tensor imaging and two-photon microscopy of CLARITY intact brains (2017) · cites this paper as Roach et al., 1985
Citations
Cites
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Southern, E. M. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80083-0 · Cited by 32,245
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
[57] Sequencing end-labeled DNA with base-specific chemical cleavages
Maxam, A. M., & Gilbert, W. (1980) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 13,943
Rigby, P. W. J., Dieckmann, M., Rhodes, C., & Berg, P. R. (1977) · Journal of Molecular Biology · doi:10.1016/0022-2836(77)90052-3 · Cited by 11,400
A general method for isolation of high molecular weight DNA from eukaryotes
Blin, N., & Stafford, D. W. (1976) · Nucleic Acids Research · doi:10.1093/nar/3.9.2303 · Cited by 2,743
Favaloro, J. M., Treisman, R., & Kamen, R. (1980) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(80)65070-8 · Cited by 1,292
Methylmercury as a reversible denaturing agent for agarose gel electrophoresis
Bailey, J. M., & Davidson, N. (1976) · Analytical Biochemistry · doi:10.1016/s0003-2697(76)80049-8 · Cited by 1,286
Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene
McKnight, S. L., & Kingsbury, R. (1982) · Science · doi:10.1126/science.6283634 · Cited by 1,259
Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes
Treisman, R., Orkin, S. H., & Maniatis, T. (1983) · Nature · doi:10.1038/302591a0 · Cited by 590
Dierks, P. M., van Ooyen, A., Cochran, M. D., Dobkin, C., Reiser, J., & Weissmann, C. (1983) · Cell · doi:10.1016/0092-8674(83)90055-7 · Cited by 538
Cited by
Sorted by citations
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
Baumann, N., & Pham-Dinh, D. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.871 · Cited by 1,828
Myelination of the Nervous System: Mechanisms and Functions
Nave, K.-A., & Werner, H. B. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013101 · Cited by 983
Axonal Swellings and Degeneration in Mice Lacking the Major Proteolipid of Myelin
Griffiths, I., Klugmann, M., Anderson, T., Yool, D., Thomson, C., Schwab, M. H., Schneider, A., Zimmermann, F., McCulloch, M., Nadon, N., et al. (1998) · Science · doi:10.1126/science.280.5369.1610 · Cited by 889
Myelin in the Central Nervous System: Structure, Function, and Pathology
Stadelmann, C., Timmler, S., Barrantes‐Freer, A., & Simons, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00031.2018 · Cited by 799
Stolt, C. C., Rehberg, S., Ader, M., Lommes, P., Riethmacher, D., Schachner, M., Bartsch, U., & Wegner, M. (2002) · Genes & Development · doi:10.1101/gad.215802 · Cited by 673
Metadata
- Authors
- ROACH, A., TAKAHASHI, N., PRAVTCHEVA, D., RUDDLE, F., & HOOD, L.
- Affiliations
- California Institute of Technology (US)
- Yale University (US)
- ORCID
- HOOD, L
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1985-08
- Volume
- 42
- Issue
- 1
- Pages
- 149-155
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2151814085
- Cited by
- 336
- References
- 32
- Citations by year
- 2025: 5 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 3 · 2019: 3 · 2018: 6 · 2017: 4 · 2016: 13 · 2015: 6 · 2014: 5 · 2013: 6 · 2012: 3
- FWCI
- 21.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Hereditary Neurological Disorders
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- myelin basic protein, chromosome 18, gene mapping, partial gene deletion, CNS myelination, alternative splicing, transcription initiation, polyadenylation, exon deletion
- MeSH terms
- Animals, Base Sequence, Brain, Chromosome Deletion, Chromosome Mapping, Myelin Basic Protein, Genes, Genetic Linkage, Mice, Neurologic Mutants, Mutation, Poly A, RNA Splicing, RNA, Messenger, Transcription, Genetic, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
