The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Cold feet and prolonged sleep-onset latency in vasospastic syndrome
Abstract
People with vasospastic syndrome have cold hands and feet and abnormal vasoconstriction after local cold exposure. Normally there is a circadian rhythm of distal vasodilation, with onset in the early evening, which directly influences ability to fall asleep. We gave a sleep questionnaire to 32 patients with primary vasospastic syndrome and 31 healthy controls. People with vasospasticity had significantly prolonged sleep-onset latency both at onset of night-time sleep and after nocturnal disturbance. This prolonged latency could be associated with impaired capacity for distal vasodilation.
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“The same association was shown for people with a vasospastic syndrome, who have a lower temperature of their hands and tend to have difficulties falling asleep [64]”
From Sleep, vigilance, and thermosensitivity (2012) · cites this paper as [64]
Citations
Cites
Warm feet promote the rapid onset of sleep
Kräuchi, K., Cajochen, C., Werth, E., & Wirz-Justice, A. (1999) · Nature · doi:10.1038/43366 · Cited by 398
Self-citationVasospasm, its Role in the Pathogenesis of Diseases with Particular Reference to the Eye
Flammer, J., Pache, M., & Resink, T. J. (2001) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(00)00028-8 · Cited by 383
Self-citationTHE SLEEP OF HEALTHY PEOPLE—A DIARY STUDY
Monk, T. H., Buysse, D. J., Rose, L. R., Hall, J. A., & Kupfer, D. J. (2000) · Chronobiology International · doi:10.1081/cbi-100101031 · Cited by 105
Mahler, F., Saner, H. E., Würbel, H., & Flammer, J. (1989) · PubMed · Cited by 40
Self-citationMicrovasculatory Evaluation of Vasospastic Syndromes
Saner, H. E., Würbel, H., Mahler, F., Flammer, J., & Gasser, P. J. (1987) · Springer eBooks · doi:10.1007/978-1-4613-1927-6_38 · Cited by 33
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Sleep-dependent modulation of thalamic brain temperature estimates in humansPreprint
Hoekstra, M. M., Lehmann, M., Gascho, D., Verstreken, P., Schmidt, C., Landolt, H., & Zoelch, N. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.08.757550
Verlaufskontrolle des Normaldruckglaukoms
Pache, M. (2007) · Springer eBooks · doi:10.1007/978-3-540-74919-6_10
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Metadata
- Authors
- Pache, M., Kräuchi, K., Cajochen, C., Wirz-Justice, A., Dubler, B., Flammer, J., & Kaiser, H. J.
- Affiliations
- Universitäre Psychiatrische Kliniken Basel (CH)
- Corresponding author
- Pache, Mona
- ORCID
- Cajochen, Christian
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 358
- Issue
- 9276
- Pages
- 125-126
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1992460259
- Cited by
- 104
- References
- 5
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 7 · 2021: 6 · 2020: 2 · 2019: 8 · 2018: 6 · 2017: 5 · 2016: 5 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 3
- FWCI
- 5.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- FreiDok plus (Universitätsbibliothek Freiburg) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Clinical Neurology › Restless Legs Syndrome Research
- Health Sciences › Medicine › Physiology (medical) › Thermoregulation and physiological responses
- Keywords
- cold hands and feet, sleep latency, circadian rhythm, vasoconstriction, nocturnal sleep disturbance
- MeSH terms
- Adult, Aged, Constriction, Pathologic, Female, Foot, Humans, Hypothermia, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Predictive Value of Tests, Surveys and Questionnaires, Risk Factors, Syndrome, Vasodilation, Case-Control Studies, Sleep Disorders, Circadian Rhythm
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