Cited by 399Sleep and Wakefulness ResearchSleep and related disordersCircadian rhythm and melatonin

Warm feet promote the rapid onset of sleep

Kräuchi, Kurt, Cajochen, Christian, Werth, Esther, Wirz-Justice, Anna·1999·Nature

Integrity signals

Registry

Crossref · 10.1038/43366

Cites

6 of 6 references verified0 citation errors · 0 not checkable

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  • The distal-proximal gradient (DPG) is associated with subjective sleepiness and sleep onset latency.

    “the distal-proximal gradient (DPG, i.e., difference between skin temperature at distal and proximal locations), which has also been shown to be associated with subjective sleepiness [31] and sleep onset latency [32].”
  • Several mechanisms provide a rationale for the improvement in insomnia symptoms from exercise, including reducing core body temperature for sleep onset, increasing melatonin and serotonin secretion, reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal associated with insomnia.

    “Several mechanisms that provide a rationale for the improvement in insomnia symptoms from exercise have been suggested [133,136,137,138,139]; these include but are not limited to reducing core body temperature for sleep onset [140,141,142,143], increasing melatonin and serotonin secretion [131,144], reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal”
  • Healthy people fall asleep more easily if their skin temperature or bed temperature is higher.

    “Healthy people fall asleep more easily if their skin temperature or bed temperature is higher [47, 48, 93].”

    From Sleep, vigilance, and thermosensitivity (2012) · cites this paper as [47]

  • It has been proposed that the gradient between temperatures measured at a distal and a proximal site correlates most strongly with measures of vigilance.

    “Based on these controlled studies, it has been proposed that it may especially be the gradient between the temperatures measured at a distal and a proximal site that correlates most strongly with measures of vigilance [46–49].”

    From Sleep, vigilance, and thermosensitivity (2012) · cites this paper as [47]

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Authors
Kräuchi, K., Cajochen, C., Werth, E., & Wirz-Justice, A.
Affiliations
Universitäre Psychiatrische Kliniken Basel (CH)
Corresponding author
Kräuchi, Kurt
Venue
Nature
Published
1999-09
Volume
401
Issue
6748
Pages
36-37
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W1559653492
Cited by
398
References
6
Citations by year
2026: 22 · 2025: 21 · 2024: 20 · 2023: 17 · 2022: 26 · 2021: 24 · 2020: 17 · 2019: 25 · 2018: 24 · 2017: 13 · 2016: 16 · 2015: 11 · 2014: 9 · 2013: 18 · 2012: 11
FWCI
4.25
Type
journal article
Language
en
Open access
closed
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords
sleep onset, sleep initiation, skin blood flow, peripheral vasodilation, thermoregulation
MeSH terms
Body Temperature, Foot, Hand, Humans, Male, Regional Blood Flow, Skin, Skin Temperature, Sleep, Vasodilation

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