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Cited by 347

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Early identification of atopy in the prediction of persistent asthma in children

Open access
Sly, Peter D, Boner, Attilio L, Björksten, Bengt, Bush, Andy, Custovic, Adnan, Eigenmann, Philippe A, Gern, James E, Gerritsen, Jorrit, Hamelmann, Eckard, Helms, Peter J, Lemanske, Robert F, Martinez, Fernando, Pedersen, Soren, Renz, Harald, Sampson, Hugh, von Mutius, Erika, Wahn, Ulrich, Holt, Patrick G·2008·The Lancet

Abstract

Summary There is a growing consensus that the long term solution to the asthma epidemic lies in prevention and not in treatment of established disease. Atopic asthma arises from gene x environment interactions which most commonly occur during a relatively narrow window period in pre- and postnatal development. These interactions are incompletely understood, and hence the holy grail of primary prevention remains an elusive goal. We contend that a lack of understanding of the role of atopy in early life in the development of persistent asthma in children exists amongst primary care physicians, paediatricians and specialists. In this review we argue that early identification of high risk children is feasible based on currently available technology, and worthwhile in relation to potential benefits to the children so identified. Knowledge of an asthmatic child's atopic status in early life has practical clinical and prognostic implications, as well as forming the basis for future preventative strategies.

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Metadata

Authors
Sly, P. D., Boner, A. L., Björksten, B., Bush, A., Custovic, A., Eigenmann, P. A., Gern, J. E., Gerritsen, J., Hamelmann, E., Helms, P. J., Lemanske, R. F., Martinez, F., Pedersen, S., Renz, H., Sampson, H., von Mutius, E., Wahn, U., & Holt, P. G.
Venue
The Lancet
Publisher
Elsevier BV
Published
2008-09
Volume
372
Issue
9643
Pages
1100-1106
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2170623205
Cited by
347
References
13
FWCI
18.10
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Early identification of atopy in the prediction of persistent asthma in children. https://app.cochat.ai/papers/10.1016/s0140-6736(08)61451-8
The paper
Sly, P. D., Boner, A. L., Björksten, B., Bush, A., Custovic, A., Eigenmann, P. A., Gern, J. E., Gerritsen, J., Hamelmann, E., Helms, P. J., Lemanske, R. F., Martinez, F., Pedersen, S., Renz, H., Sampson, H., von Mutius, E., Wahn, U., & Holt, P. G. (2008). Early identification of atopy in the prediction of persistent asthma in children. The Lancet. https://doi.org/10.1016/s0140-6736(08)61451-8

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.