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Cited by 1,431Hyperglycemia and glycemic control in critically ill and hospitalized patientsDiabetes Management and ResearchDiabetes Treatment and Management

Stress hyperglycaemia

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Dungan, Kathleen M, Braithwaite, Susan S, Preiser, Jean-Charles·2009·The Lancet
DOI 10.1016/s0140-6736(09)60553-5PMC PMC3144755
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Abstract

Results of randomised controlled trials of tight glycaemic control in hospital inpatients might vary with population and disease state. Individualised therapy for different hospital inpatient populations and identification of patients at risk of hyperglycaemia might be needed. One risk factor that has received much attention is the presence of pre-existing diabetes. So-called stress hyperglycaemia is usually defined as hyperglycaemia resolving spontaneously after dissipation of acute illness. The term generally refers to patients without known diabetes, although patients with diabetes might also develop stress hyperglycaemia-a fact overlooked in many studies comparing hospital inpatients with or without diabetes. Investigators of several studies have suggested that patients with stress hyperglycaemia are at higher risk of adverse consequences than are those with pre-existing diabetes. We describe classification of stress hyperglycaemia, mechanisms of harm, and management strategies.

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Authors
Dungan, K. M., Braithwaite, S. S., & Preiser, J.-C.
Affiliations
  • The Ohio State University (US)
  • University of North Carolina at Chapel Hill (US)
  • Centre Hospitalier Universitaire de Liège (BE)
Corresponding author
Dungan, Kathleen M
ORCID
Venue
The Lancet
Publisher
Elsevier BV
Published
2009-05
Volume
373
Issue
9677
Pages
1798-1807
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(09)60553-5
PMC
PMC3144755
OpenAlex
W4211084754
Cited by
1,431
References
12
Citations by year
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FWCI
5.16
Type
journal article
Language
en
Open access
Licence
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
  • Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
  • UNC Libraries
Funders
  • Eli Lilly and Company
  • Novo Nordisk
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords
stress hyperglycemia, tight glycemic control, hospitalized patients, pregestational diabetes, risk factors, management strategies, adverse outcomes
MeSH terms
Acute Disease, Blood Glucose, Cardiovascular Diseases, Glucose Tolerance Test, Humans, Hyperglycemia, Monitoring, Physiologic, Prediabetic State, Research Design, Risk Factors, Severity of Illness Index, Stress, Physiological, Surgical Procedures, Operative, Prevalence, Critical Illness, Treatment Outcome, Stroke, Risk Reduction Behavior, Early Diagnosis

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