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50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Open accessAbstract
Background Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.Methods We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex.Findings During 50 years of observation (202,417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset.Interpretation Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.Funding NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft.
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In the citing paper
“Similarly to incidence, age-adjusted prevalence of AF has been reported to be lower in women than in men in North America and Europe (Figure 2) (Supplementary Tables S3 and S4).”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
Experimental — accuracy not yet measuredIn the citing paper
“Hypertension (treated) vs. none 19 HR 1.32 (95% CI 1.08-1.60)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Heart failure vs. none 19 HR 1.43 (95% CI 0.85-2.40)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Older age 19 50-59 years 60-69 years 70-79 years 80-89 years HR: 1.00 (reference) 4.98 (95% CI 3.49-7.10) 7.35 (95% CI 5.28-10.2) 9.33 (95% CI 6.68-13.0)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Obesity 19, 208 none (BMI < 25 kg/m²) overweight (BMI 25-30 kg/m²) obese (BMI ≥ 31 kg/m²) HR: 1.00 (reference) 1.13 (95% CI 0.87-1.46)1.37 (95% CI 1.05-1.78)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Myocardial infarction vs. none 19 HR 1.46 (95% CI 1.07-1.98)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Diabetes mellitus vs. none 19 HR 1.25 (95% CI 0.98-1.60)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“In North American and European populations, the age-adjusted incidence of AF has been estimated to be 1.5 to 2 times higher in men than in women (Supplementary Tables S1 and S2).”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“Elevated body mass index, hypertension, diabetes mellitus, coronary heart disease, valvular heart disease, and heart failure (HF) constitute major risk factors for AF, but the prevalence of these risk factors vary between women and men.3–5”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“Women with AF have higher prevalence of hypertension and valvular heart disease and lower prevalence of coronary heart disease than men with AF.5,11,34”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“However, in studies from North America,5 Europe,34,35 and Australia,11 women with AF are, on average, older than men.”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“In particular, body mass index has increased significantly (Figure 3).5”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
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Citations
Cites
Regression Analysis of Count Data
Cameron, A. C., & Trivedi, P. K. (2013) · doi:10.1017/cbo9781139013567 · Cited by 6,640
Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001) · JAMA · doi:10.1001/jama.285.18.2370 · Cited by 6,205
Burden of valvular heart diseases: a population-based study
Nkomo, V. T., Gardin, J. M., Skelton, T. N., Gottdiener, J. S., Scott, C. G., & Enriquez-Sarano, M. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69208-8 · Cited by 4,881
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study
Chugh, S. S., Havmoeller, R., Narayanan, K., Singh, D., Rienstra, M., Benjamin, E. J., Gillum, R. F., Kim, Y.-H., McAnulty, J. H., Zheng, Z.-J., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.005119 · Cited by 4,506
Self-citationExplaining the decrease in U.S. deaths from coronary disease, 1980–2000
Ford, E. S., Ajani, U. A., Croft, J. B., Critchley, J. A., Labarthe, D. R., Kottke, T. E., Giles, W. H., & Capewell, S. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa053935 · Cited by 2,757
Benjamin, E. J. (1994) · JAMA · doi:10.1001/jama.1994.03510350050036 · Cited by 2,613
Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008
Egan, B. M. (2010) · JAMA · doi:10.1001/jama.2010.650 · Cited by 2,197
Long-term trends in the incidence of and survival with heart failure
Levy, D., Kenchaiah, S., Larson, M. G., Benjamin, E. J., Kupka, M. J., Ho, K. K. L., Murabito, J. M., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020265 · Cited by 2,152
Self-citation
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Eickholt, C., Jungen, C., Drexel, T., Alken, F., Kuklik, P., Muehlsteff, J., Makimoto, H., Hoffmann, B. A., Kelm, M., Ziegler, D., et al. (2018) · Medical Science Monitor · doi:10.12659/msm.905209 · Cited by 19
Fan, X., Li, Y., He, Q., Wang, M., Lan, X., Zhang, K., Ma, C., & Zhang, H. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2411315 · Cited by 16
Inflammation pathways as therapeutic targets in angiotensin II induced atrial fibrillation
Hou, A., Shi, D., Huang, H., Liu, Y., & Zhang, Y. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1515864 · Cited by 16
Kim, J., Lee, J. S., Kim, B. J., Park, J., Kang, K., Lee, S. J., Kim, J. G., Cha, J., Kim, D.-H., Park, T. H., et al. (2020) · Translational Stroke Research · doi:10.1007/s12975-020-00822-z · Cited by 16
Association of systolic blood pressure with atrial fibrillation among treated hypertensive patients
Chen, C., Liu, L., Yu, Y., Shen, G., Huang, J., Huang, Y., Lo, K. K.-H., Tang, S., & Feng, Y. (2020) · Annals of Palliative Medicine · doi:10.21037/apm-19-649 · Cited by 16
Zhao, Q., Shi, S., Huang, H., Jiang, H., Yang, B., Wu, G., Bao, M., Liu, Y., Tang, Y., Wang, X., et al. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000001151 · Cited by 16
Sheng, X., Pan, Y., Yu, C., Wang, B., Zhang, P., Li, J., Zhang, J., Chen, S., Wang, M., Sun, Y., et al. (2021) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14331 · Cited by 16
Billur, D., Olğar, Y., & Turan, B. (2022) · Journal of Histochemistry & Cytochemistry · doi:10.1369/00221554221101661 · Cited by 16
Zhou, Y., Zha, L., & Pan, S. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.72334 · Cited by 16
Sharashova, E., Gerdts, E., Ball, J., Espnes, H., Jacobsen, B. K., Kildal, S., Mathiesen, E. B., Njølstad, I., Rosengren, A., Schirmer, H., et al. (2022) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwac234 · Cited by 16
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Leiva, O., Bohart, I., Ahuja, T., & Park, D. S. (2023) · Cardiology · doi:10.1159/000529260 · Cited by 17
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Lee, H., Rhee, T., Choi, J. M., Choi, S., & Kim, D. W. (2025) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2024.10.005 · Cited by 19
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van Laar, C., Geuzebroek, G. S. C., Hofman, F. N., & van Putte, B. P. (2016) · Multimedia Manual of Cardio-Thoracic Surgery · doi:10.1093/mmcts/mmv043 · Cited by 16
Influence of abdominal obesity and habitual behaviors on incident atrial fibrillation in Japanese
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Mahajan, R., & Wong, C. X. J. (2021) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2020.11.006 · Cited by 16
Zhang, Q., Zhang, X., Zhang, J., Wang, B., Meng, X., Tian, Q., Zhang, J., Jiang, M., Zhang, Y., Zheng, D., et al. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.769198 · Cited by 16
Wodschow, K., Villanueva, C. M., Larsen, M. L., Gislason, G., Schullehner, J., Hansen, B., & Ersbøll, A. K. (2021) · Environmental Health · doi:10.1186/s12940-021-00813-z · Cited by 17
Amabile, A., Fereydooni, S., Mori, M., Hameed, I., Jung, J., Krane, M., & Geirsson, A. (2022) · Journal of Cardiac Surgery · doi:10.1111/jocs.16312 · Cited by 16
Brundel, B. J. J. M., Ai, X., Hills, M. T., Kuipers, M. F., Lip, G. Y. H., & de Groot, N. M. S. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.17 · Cited by 18
Díez‐Villanueva, P., Cosı́n-Sales, J., Roldán, V., Barrios, V., Riba-Artés, D., & Gavín‐Sebastián, O. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12031224 · Cited by 16
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Lee, C. W., Muo, C., Liang, J., Lin, M., & Kao, C. (2016) · Medicine · doi:10.1097/md.0000000000003102 · Cited by 16
Teuwen, C. P., Korevaar, T. I. M., Coolen, R. L., van der Wel, T., Houck, C. A., Evertz, R., Yaksh, A., Roos‐Hesselink, J. W., Bogers, A. J. J. C., & de Groot, N. M. S. (2016) · EP Europace · doi:10.1093/europace/euw300 · Cited by 16
Islam, M. S., Ammour, N., & Alajlan, N. (2017) · International Conference on Informatics, Health & Technology (ICIHT) · doi:10.1109/iciht.2017.7899003 · Cited by 16
Rewiuk, K., Wizner, B., Klich‐Rączka, A., Więcek, A., Mossakowska, M., Chudek, J. T., Szybalska, A., Broczek, K. M., Zdrojewski, T. R., & Grodzicki, T. K. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.09.006 · Cited by 17
Semmler, V., von Krogh, F., Haller, B., Reents, T., Bourier, F. J., Telishevska, M., Kottmaier, M., Kornmayer, M., Brooks, S., Koch‐Büttner, K., et al. (2018) · Clinical Research in Cardiology · doi:10.1007/s00392-018-1393-1 · Cited by 16
Su, C., Liu, Z., Gao, Y., Liu, Y., Hu, R., Liu, J., Yang, X., Li, S., Zhang, Y., Zuo, K., et al. (2019) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.13958 · Cited by 16
Prävalenz und Risikofaktoren von Vorhofflimmern in Deutschland
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Qin, S., Zhu, C., Chen, C., Sheng, Z., & Cao, Y. (2024) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2024.5457 · Cited by 15
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Cheng, Y., Deng, H., Wei, H., Lin, W., Liang, Z., Chen, Y., Dong, Y., Fang, X., Liao, H., Wu, S., et al. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.038367 · Cited by 15
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Anti-inflammatory HDL effects are impaired in atrial fibrillation
Holzwirth, E., Fischer-Schaepmann, T., Obradović, D., von Lucadou, M., Schwedhelm, E., Daum, G., Hindricks, G., Marsche, G., Trieb, M., Thiele, H., et al. (2021) · Heart and Vessels · doi:10.1007/s00380-021-01908-w · Cited by 15
Dai, H., Tang, B., Younis, A., Kong, J. D., Zhong, W., & Bragazzi, N. L. (2021) · BMJ Global Health · doi:10.1136/bmjgh-2021-006809 · Cited by 15
Cardiorespiratory fitness, obesity and left atrial function in patients with atrial fibrillation
Mishima, R. S., Ariyaratnam, J., Pitman, B. M., Malik, V., Emami, M., McNamee, O., Stokes, M. B., Lau, D. H., Sanders, P., & Elliott, A. D. (2022) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2022.101083 · Cited by 15
Huang, Y., Xie, Y., Huang, L., & Han, Z. (2023) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s395578 · Cited by 15
Fatima, K., Asad, D., Shaikh, N., Ansari, S. A., Kumar, G., Rehman, H. A., Azam, F., Khan, S. A., Ahmed, S., Shah, A., et al. (2023) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2023.04.038 · Cited by 15
Pathophysiology, molecular mechanisms, and genetics of atrial fibrillation
Han, P., Zhao, X., Li, X., Geng, J., Ni, S., & Li, Q. (2024) · Human Cell · doi:10.1007/s13577-024-01145-z · Cited by 16
Padula, W. V., Paffrath, A., Jacobsen, C. M., Cohen, B. G., Nadboy, R., Sutton, B. S., Gerstenfeld, E. P., MANSOUR, M. C., & Reddy, V. Y. (2024) · Journal of Medical Economics · doi:10.1080/13696998.2024.2441071 · Cited by 15
Obesity and Atrial Fibrillation: A Comprehensive Review
Na, J. S., Garapati, S. S., & Lador, A. (2025) · Methodist DeBakey Cardiovascular Journal · doi:10.14797/mdcvj.1516 · Cited by 19
Epidemiología de la fibrilación auricular
Gómez‐Doblas, J. J., López-Garrido, M. A., Ruiz, I. E., & Barón‐Esquivias, G. (2016) · Revista Española de Cardiología Suplementos · doi:10.1016/s1131-3587(16)30007-3 · Cited by 16
Waveform Integrity in Atrial Fibrillation: The Forgotten Issue of Cardiac Electrophysiology
Martínez, M. S., Ródenas, J., Alcaraz, R., & Rieta, J. J. (2017) · Annals of Biomedical Engineering · doi:10.1007/s10439-017-1832-6 · Cited by 15
Schwill, S., Krug, K., Peters-Klimm, F., van Lieshout, J., Laux, G., Szécsényi, J., & Wensing, M. (2018) · BMC Family Practice · doi:10.1186/s12875-018-0796-4 · Cited by 15
Shao, M.-J., Shang, L.-X., Shi, J., Zhao, Y., Zhang, W.-H., Zhang, L., Li, Y.-D., Tang, B., & Zhou, X.-H. (2018) · PLoS ONE · doi:10.1371/journal.pone.0206362 · Cited by 15
Cai, J., Cheng, J., Li, H., Lin, W., Li, Y., Zhuo, X., Huang, X., Simone, C. B., Aronow, W. S., Chow, E., et al. (2018) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2018.11.008 · Cited by 15
Left Atrial Appendage Occlusion: A Narrative Review
Alsagheir, A., Koziarz, A., Belley‐Côté, E. P., & Whitlock, R. P. (2019) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2019.01.054 · Cited by 15
Yassin, A., Subahi, A., Adegbala, O. M., Abubakar, H., Dawdy, J. A., Mishra, T., Akintoye, E. O., Shereef, H., Ghandour, M. M., Alhusain, R., et al. (2019) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2019.07.022 · Cited by 15
Jansson, M., Själander, S., Sjögren, V., Renlund, H., Norrving, B. G., & Själander, A. (2019) · Thrombosis Research · doi:10.1016/j.thromres.2019.11.010 · Cited by 16
Han, H., Chen, L., Lin, Z., Wei, X., Guo, W. P., Yu, Y., Wu, C., Cao, Y., & He, J. (2021) · Cancer Medicine · doi:10.1002/cam4.4105 · Cited by 15
Noubiap, J. J., Thomas, G., Agbaedeng, T. A., Fitzgerald, J. L., Gallagher, C., Middeldorp, M. E., & Sanders, P. (2021) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcab096 · Cited by 15
Sano, T., Matsumoto, S., Ikeda, T., Kuroda, S., Kitai, T., Yonetsu, T., Kohsaka, S., Torii, S., Node, K., & Matsue, Y. (2022) · Circulation Journal · doi:10.1253/circj.cj-21-0911 · Cited by 15
Sex-linked genetic mechanisms and atrial fibrillation risk
Wren, G. H., & Davies, W. (2022) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2022.104459 · Cited by 15
Amaya‐Pascasio, L., Quesada‐López, M., García‐Torrecillas, J. M., Padillo, A. A., & Martínez‐Sánchez, P. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.900582 · Cited by 15
Serum brain-derived neurotrophic factor and risk of atrial fibrillation
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Shehab, A., Zubaid, M., Bhagavathula, A. S., Rashed, W. A., Alsheikh-Ali, A. A. A., Almahmeed, W. A., Sulaiman, K., Al-Zakwani, I. S., AlQudaimi, A., Asaad, N., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175405 · Cited by 15
Zhou, L., Zhang, Q., Luo, H., Yu, K., Meng, X., Chen, R., & Kan, H. (2024) · Eco-Environment & Health · doi:10.1016/j.eehl.2024.05.006 · Cited by 14
Askarinejad, A., Lane, D. A., Sadeghipour, P., Haghjoo, M., & Lip, G. Y. H. (2025) · European Journal of Clinical Investigation · doi:10.1111/eci.70082 · Cited by 16
Antoun, I., Layton, G., Abdelrazik, A., Eldesouky, M., Davies, H., Barakat, O., Mahfoud, A., Koya, A., Lau, E., Zakkar, M., et al. (2025) · Cardiovascular Electrophysiology · doi:10.1111/jce.70063 · Cited by 11
Geurts, S., Mens, M. M. J., Bos, M. M., Ikram, M. A., Ghanbari, M., & Kavousi, M. (2021) · Genes · doi:10.3390/genes13010011 · Cited by 14
Yue, W., Wang, L., Lin, C., Xie, Y., Bao, Y., Luo, Q., & Zhang, N. (2021) · Medicine · doi:10.1097/md.0000000000027749 · Cited by 14
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Albertsen, N., Riahi, S., Pedersen, M., Skovgaard, N., & Andersen, S. (2022) · International Journal of Circumpolar Health · doi:10.1080/22423982.2022.2030522 · Cited by 14
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Choi, S. H., Yang, P., Kim, D., Sung, J., Jang, E., Yu, H. T., Kim, T., Pak, H., Lee, M., Lip, G. Y. H., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-32229-9 · Cited by 14
Xu, M., Song, Z., Hong, W., Wang, L., Jiang, C., Yang, B. T., Qin, M., & Liu, J. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202302041 · Cited by 15
Zhao, S. X., Tindle, H., Larson, J. C., Woods, N., Crawford, M. H., Hoover, V. J., Salmoirago-blotcher, E., Shadyab, A., Stefanick, M., & Perez, M. V. (2023) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.123.030030 · Cited by 10
Grzeczka, A., Graczyk, S., & Kordowitzki, P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115699 · Cited by 14
Trends in atrial fibrillation-related mortality in Europe, 2008–2019
Zuin, M., Malagù, M., Vitali, F., Balla, C., Raffele, M. D., Ferrari, R., Boriani, G., & Bertini, M. (2024) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcae007 · Cited by 14
Clinical Impact of Early Rhythm Control and Healthy Lifestyles in Patients With Atrial Fibrillation
Lee, S., Choi, E., Lee, S. W., Han, K., Oh, S., & Lip, G. Y. H. (2024) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2024.02.016 · Cited by 14
Atrial fibrillation fact sheet in Korea 2024 (part 1): epidemiology of atrial fibrillation in Korea
Lee, S., Kim, D., Lee, S. H., Lim, W., Chun, K. J., Choe, W.-S., Ahn, H., Lee, K., Choi, J., Kim, B., et al. (2024) · International Journal of Arrhythmia · doi:10.1186/s42444-024-00119-4 · Cited by 14
Amin, A. M., Elbenawi, H., Khan, U., Almaadawy, O., Turkmani, M. M., Abdelmottaleb, W., Essa, M., Abuelazm, M. T., Abdelazeem, B., Asad, Z. U. A., et al. (2025) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.124.013261 · Cited by 14
Antoun, I., Layton, G. R., Abdelrazik, A., Eldesouky, M., Zakkar, M., Somani, R., & Ng, G. A. (2025) · Medicina · doi:10.3390/medicina61040649 · Cited by 14
Use of Direct-Acting Oral Anticoagulants in Nonagenarians: A Call for More Data
Stöllberger, C., Brooks, R., Finsterer, J., & Pachofszky, T. (2016) · Drugs & Aging · doi:10.1007/s40266-016-0363-4 · Cited by 14
Huang, T., Lo, L., Yamada, S., Chou, Y., Lin, W., Chang, S., Lin, Y., Liu, S.-H., Cheng, W., Tsai, T., et al. (2019) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14181 · Cited by 14
Integrative Analysis of miRNA and mRNA Expression Profiles Associated With Human Atrial Aging
Yao, Y., Jiang, C., Wang, F., Yan, H., Long, D., Zhao, J., Wang, J., Zhang, C., Li, Y., Tian, X., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01226 · Cited by 17
Mechanisms of Chronic Metabolic Stress in Arrhythmias
Gowen, B. H., Reyes, M. V., Joseph, L. C., & Morrow, J. (2020) · Antioxidants · doi:10.3390/antiox9101012 · Cited by 16
Postoperative Atrial Fibrillation in Coronary Artery Bypass Grafting Herald Poor Outcome
Malhotra, P., Pande, S., Mahindru, S., Thukral, A., Kotwal, A. S., Gupta, R. P., Tewari, P., & Agarwal, S. K. (2021) · Annals of Cardiac Anaesthesia · doi:10.4103/aca.aca_30_20 · Cited by 14
Haq, I.-U., Akhiyat, N., Rmilah, A. A. A., Alzu’bi, H., Kowlgi, G. N., Lee, H.-C., Asirvatham, S. J., Deshmukh, A. J., & DeSimone, C. V. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01341-7 · Cited by 14
Cho, Y. Y., Kim, B., Choi, D., Kim, C., Shin, D. W., Kim, J. S., Park, S., Kim, S. W., Chung, J. H., Han, K., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1032764 · Cited by 14
Interleukin‐37 elevation in patients with atrial fibrillation
Li, W., Li, S., Li, X., Jiang, S., & Han, B. (2016) · Clinical Cardiology · doi:10.1002/clc.22630 · Cited by 14
Liu, C., & Chen, H.-C. (2016) · Clinical Drug Investigation · doi:10.1007/s40261-016-0487-7 · Cited by 15
Ródenas, J., García, M., Alcaraz, R., & Rieta, J. J. (2017) · Complexity · doi:10.1155/2017/2163610 · Cited by 14
Zhang, J., Ren, Z., Wang, S., Zhang, J., Yang, H., Zheng, Y., Meng, W., Zhao, D., & Xu, Y. (2019) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14220 · Cited by 14
Lifestyle Modification and Atrial Fibrillation: Critical Care for Successful Ablation
Fitzgerald, J. L., Middeldorp, M. E., Gallagher, C., & Sanders, P. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11092660 · Cited by 13
Vyas, V., Vyas, V., Sharma, A., & Kumar, P. A. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm39233 · Cited by 15
Sleep Disruption and Atrial Fibrillation: Evidence, Mechanisms and Clinical Implications
Deshmukh, A. J., Covassin, N., Dauvilliers, Y. A., & Somers, V. K. (2025) · Circulation Research · doi:10.1161/circresaha.125.325612 · Cited by 14
Ткачева, О. Н., Vorobyeva, N. M., Kotovskaya, Y. V., Рунихина, Н. К., Strazhesko, I. D., Вадимовна, В. С., Drapkina, O. M., Komarov, A. L., Orlova, Y. A., Панченко, Е. П., et al. (2021) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2021-2847 · Cited by 14
Liu, X., Gao, X., Chen, L., Shen, L., Liu, M., & Xu, Y. (2022) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14591 · Cited by 12
Preprocedural Multimodality Imaging in Atrial Fibrillation
Quintana, R. A., Dong, T. A., Vajapey, R. S., Reyaldeen, R. M., Kwon, D. H., Harb, S. C., Wang, T. K. M., & Klein, A. L. (2022) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.122.014386 · Cited by 13
Harada, M., Okuzaki, D., Yamauchi, A., Ishikawa, S., Nomura, Y., Nishimura, A., Motoike, Y., Koshikawa, M., Hitachi, K., Tsuchida, K., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0283942 · Cited by 13
Hirose, K., Nakanishi, K., Daimon, M., Iwama, K., Yoshida, Y., Mukai, Y., Yamamoto, Y., Nakao, T., Oshima, T., Matsubara, T. J., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.032215 · Cited by 13
Rodrigues, T. S., Quarto, L. J. G., Nogueira, S. C., Koshy, A. N., Mahajan, R., Sanders, P., Ekinci, E. I., Burrell, L. M., Farouque, O., & Lim, H. S. (2024) · Clinical Research in Cardiology · doi:10.1007/s00392-023-02349-3 · Cited by 13
Miyauchi, S., Ouhara, K., Shintani, T., Tokuyama, T., Okubo, Y., Okamura, S., Miyamoto, S., Oguri, N., Uotani, Y., Takemura, T., et al. (2024) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.123.033740 · Cited by 10
Li, L., Wang, C., Ye, Z., Spall, H. G. C. V., Zhang, J., Lip, G. Y. H., & Li, G. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.033840 · Cited by 13
Machine Learning Predicts Bleeding Risk in Atrial Fibrillation Patients on Direct Oral Anticoagulant
Chaudhary, R., Nourelahi, M., Thoma, F. W., Gellad, W. F., Lo‐Ciganic, W., Chaudhary, R., Dua, A., Bliden, K. P., Gurbel, P. A., Neal, M. D., et al. (2025) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2025.02.030 · Cited by 13
The Role of Arterial Hypertension in Mitral Valve Regurgitation
Katsi, V. K., Georgiopoulos, G. A., Magkas, N., Oikonomou, D., Virdis, A., Nihoyannopoulos, P., Toutouzas, K. P., & Tousoulis, D. M. (2019) · Current Hypertension Reports · doi:10.1007/s11906-019-0928-9 · Cited by 13
Metadata
- Authors
- Schnabel, R. B., Yin, X., Gona, P., Larson, M. G., Beiser, A. S., McManus, D. D., Newton-Cheh, C., Lubitz, S. A., Magnani, J. W., Ellinor, P. T., Seshadri, S., Wolf, P. A., Vasan, R. S., Benjamin, E. J., & Levy, D.
- Affiliations
- Framingham Heart Study (US)
- Boston University (US)
- University of Massachusetts Chan Medical School (US)
- Harvard University (US)
- Broad Institute (US)
- Corresponding author
- Schnabel, Renate B
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 386
- Issue
- 9989
- Pages
- 154-162
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- PMC
- PMC4553037
- OpenAlex
- W1924098982
- Cited by
- 1,746
- References
- 32
- Citations by year
- 2026: 126 · 2025: 209 · 2024: 253 · 2023: 192 · 2022: 198 · 2021: 155 · 2020: 145 · 2019: 141 · 2018: 120 · 2017: 110 · 2016: 76 · 2015: 20
- FWCI
- 79.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion)
- Funders
- NIH/NHLBI (contract N01-HC-25195, grant 1K23HL114724)
- NIH (grants 1RC1HL101056, HL102214, and AG028321, grant 2R01HL092577, grants 1U01HL105268-01 and KL2RR031981)
- Fondation Leducq (14CVD01) and NIH grants (1R01HL092577, 1RC1HL101056, 1R01HL102214, 1R01AG028321, R01HL104156, and 1K24HL105780)
- American Heart Association Established Investigator Award (13EIA14220013)
- Deutsche Forschungsgemeinschaft (German Research Foundation) Emmy Noether Program (SCHN 1149/3-2)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- atrial fibrillation, prevalence trends, incidence trends, sex differences, risk factors, stroke, mortality, Framingham Heart Study, electrocardiogram screening, atrial fibrillation screening, atrial fibrillation prevention, cardiovascular disease prevention, long-term cohort follow-up
- MeSH terms
- Aged, Aged, 80 and over, Atrial Fibrillation, Electrocardiography, Female, Humans, Male, Middle Aged, Mortality, Risk Factors, United States, Cohort Studies, Incidence, Prevalence, Age Distribution, Sex Distribution, Stroke
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