The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Open accessAbstract
Background Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years.Methods We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007. We analysed trends within 10 year groups (1958-67, 1968-77, 1978-87, 1988-97, and 1998-2007), stratified by sex.Findings During 50 years of observation (202,417 person-years), 1544 cases of new-onset atrial fibrillation occurred (of whom 723 [47%] were women). Between 1958-67 and 1998-2007, age-adjusted prevalence of atrial fibrillation quadrupled from 20·4 to 96·2 cases per 1000 person-years in men and from 13·7 to 49·4 cases per 1000 person-years in women; age-adjusted incidence increased from 3·7 to 13·4 new cases per 1000 person-years in men and from 2·5 to 8·6 new cases per 1000 person-years in women (ptrend<0·0001 for all comparisons). For atrial fibrillation diagnosed by electrocardiograph (ECG) during routine Framingham examinations, age-adjusted prevalence per 1000 person-years increased (12·6 in 1958-67 to 25·7 in 1998-2007 in men, ptrend=0·0007; 8·1 to 11·8 in women, ptrend=0·009). However, age-adjusted incidence of atrial fibrillation by Framingham Heart Study ECGs did not change significantly with time. Although the prevalence of most risk factors changed over time, their associated hazards for atrial fibrillation changed little. Multivariable-adjusted proportional hazards models revealed a 74% (95% CI 50-86%) decrease in stroke (hazards ratio [HR] 3·77, 95% CI 1·98-7·20 in 1958-1967 compared with 1998-2007; ptrend=0·0001) and a 25% (95% CI -3-46%) decrease in mortality (HR 1·34, 95% CI 0·97-1·86 in 1958-1967 compared with 1998-2007; ptrend=0·003) in 20 years following atrial fibrillation onset.Interpretation Trends of increased incidence and prevalence of atrial fibrillation in the community were probably partly due to enhanced surveillance. Measures are needed to enhance early detection of atrial fibrillation, through increased awareness coupled with targeted screening programmes and risk factor-specific prevention.Funding NIH, NHLBI, NINDS, Deutsche Forschungsgemeinschaft.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Similarly to incidence, age-adjusted prevalence of AF has been reported to be lower in women than in men in North America and Europe (Figure 2) (Supplementary Tables S3 and S4).”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
Experimental — accuracy not yet measuredIn the citing paper
“Hypertension (treated) vs. none 19 HR 1.32 (95% CI 1.08-1.60)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Heart failure vs. none 19 HR 1.43 (95% CI 0.85-2.40)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Older age 19 50-59 years 60-69 years 70-79 years 80-89 years HR: 1.00 (reference) 4.98 (95% CI 3.49-7.10) 7.35 (95% CI 5.28-10.2) 9.33 (95% CI 6.68-13.0)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Obesity 19, 208 none (BMI < 25 kg/m²) overweight (BMI 25-30 kg/m²) obese (BMI ≥ 31 kg/m²) HR: 1.00 (reference) 1.13 (95% CI 0.87-1.46)1.37 (95% CI 1.05-1.78)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Myocardial infarction vs. none 19 HR 1.46 (95% CI 1.07-1.98)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“Diabetes mellitus vs. none 19 HR 1.25 (95% CI 0.98-1.60)”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [19]
In the citing paper
“In North American and European populations, the age-adjusted incidence of AF has been estimated to be 1.5 to 2 times higher in men than in women (Supplementary Tables S1 and S2).”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“Elevated body mass index, hypertension, diabetes mellitus, coronary heart disease, valvular heart disease, and heart failure (HF) constitute major risk factors for AF, but the prevalence of these risk factors vary between women and men.3–5”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“Women with AF have higher prevalence of hypertension and valvular heart disease and lower prevalence of coronary heart disease than men with AF.5,11,34”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“However, in studies from North America,5 Europe,34,35 and Australia,11 women with AF are, on average, older than men.”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
In the citing paper
“In particular, body mass index has increased significantly (Figure 3).5”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [5]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Regression Analysis of Count Data
Cameron, A. C., & Trivedi, P. K. (2013) · doi:10.1017/cbo9781139013567 · Cited by 6,640
Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001) · JAMA · doi:10.1001/jama.285.18.2370 · Cited by 6,205
Burden of valvular heart diseases: a population-based study
Nkomo, V. T., Gardin, J. M., Skelton, T. N., Gottdiener, J. S., Scott, C. G., & Enriquez-Sarano, M. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69208-8 · Cited by 4,881
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study
Chugh, S. S., Havmoeller, R., Narayanan, K., Singh, D., Rienstra, M., Benjamin, E. J., Gillum, R. F., Kim, Y.-H., McAnulty, J. H., Zheng, Z.-J., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.005119 · Cited by 4,506
Self-citationExplaining the decrease in U.S. deaths from coronary disease, 1980–2000
Ford, E. S., Ajani, U. A., Croft, J. B., Critchley, J. A., Labarthe, D. R., Kottke, T. E., Giles, W. H., & Capewell, S. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa053935 · Cited by 2,757
Benjamin, E. J. (1994) · JAMA · doi:10.1001/jama.1994.03510350050036 · Cited by 2,613
Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008
Egan, B. M. (2010) · JAMA · doi:10.1001/jama.2010.650 · Cited by 2,197
Long-term trends in the incidence of and survival with heart failure
Levy, D., Kenchaiah, S., Larson, M. G., Benjamin, E. J., Kupka, M. J., Ho, K. K. L., Murabito, J. M., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020265 · Cited by 2,152
Self-citation
Cited by
Sorted by citations
Items 601–700 of 1,000
SS-SWT and SI-CNN: An Atrial Fibrillation Detection Framework for Time-Frequency ECG Signal
Zhang, H., He, R., Dai, H., Xu, M., & Wang, Z. (2020) · Journal of Healthcare Engineering · doi:10.1155/2020/7526825 · Cited by 12
Plasma Galectin-3 is associated with progression from paroxysmal to persistent atrial fibrillation
Wang, Q., Xu, L., Dong, Y., Fu, Y., Pan, Y., Luan, Q., Liu, Y., Liu, Z., Yang, X., Chen, M., et al. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-02043-0 · Cited by 13
Kornej, J., Huang, Q., Preis, S. R., Lubitz, S. A., Ko, D., Murabito, J. M., Benjamin, E. J., & Trinquart, L. (2021) · BMC Medicine · doi:10.1186/s12916-021-02037-x · Cited by 13
Raczkowska-Golanko, M., Raczak, G., Gruchała, M., & Daniłowicz‐Szymanowicz, L. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10163622 · Cited by 13
Automated detection of atrial fibrillation based on vocal features analysis
Golovchiner, G., Glikson, M., Swissa, M., Sela, Y., Abelow, A., Morelli, O., & Beker, A. (2022) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15595 · Cited by 13
Palà, E., Bustamante, A., Clua‐Espuny, J. L., Acosta, J., González-Loyola, F., Santos, S. D., Ribas-Seguí, D., Ballesta-Ors, J., Peñalba, A., Giralt, M., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0273571 · Cited by 13
Mouse models of spontaneous atrial fibrillation
Keefe, J. A., Hulsurkar, M. M., Reilly, S. N., & Wehrens, X. H. T. (2022) · Mammalian Genome · doi:10.1007/s00335-022-09964-x · Cited by 14
Maan, A., Jorgensen, N. W., Mansour, M., Dudley, S. C., Jenny, N. S., deFilippi, C. R., Szklo, M., Alonso, Á., Refaat, M. M., Ruskin, J. N., et al. (2016) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12969 · Cited by 12
Szmit, S., Jurczak, W. J., Zaucha, J. M., Długosz‐Danecka, M., Sosnowska‐Pasiarska, B., Chmielowska, E., Joks, M., Drozd-Sokolowska, J. E., Knopińska‐Posłuszny, W., Spychałowicz, W., et al. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.02.073 · Cited by 13
Annual rate of newly treated atrial fibrillation by age and gender in France, 2010–2016
Gabet, A., Chatignoux, É., Billionnet, C., Maura, G., Giroud, M., Béjot, Y., & Olié, V. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00594-3 · Cited by 13
Franciulli, M., Martino, G. D., Librera, M., Desoky, A., Mariniello, A., Iavazzo, A., Scigliano, F., Esposito, G., & Chiariello, L. (2020) · Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery · doi:10.1177/1556984520960116 · Cited by 13
An improved Poincaré plot-based method to detect atrial fibrillation from short single-lead ECG
Luo, C., Li, Q., Rao, H., Huang, X., Jiang, H., & Rao, N. (2020) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2020.102264 · Cited by 13
Shiyovich, A., Chodick, G., Azani, L., Tirosh, M., Shuvy, M., Pereg, D., Katz, A., & Minha, S. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247097 · Cited by 12
Li, X., Bao, Y., Jia, K., Zhang, N., Lin, C., Wei, Y., Xie, Y., Luo, Q., Ling, T., Chen, K., et al. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd9030088 · Cited by 13
Tanaka, N., Okada, M., Tanaka, K., Hirao, Y., Miyazaki, N., Iwasa, K., Koyama, Y., Iwanaga, Y., Watanabe, H., Fujii, K., et al. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.038742 · Cited by 14
Hypokalaemia and atrial fibrillation detected by implanted loop recorders
Hessellund, A. K., Kongebro, E. K., Haugan, K., Graff, C., Spona, D. C., Baadsgaard, J. A., Xing, L. Y., Højberg, S., Krieger, D. W., Brandes, A., et al. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf623 · Cited by 12
Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation
Pronto, J. R. D., Mason, F. E., Rog‐Zielinska, E. A., Fakuade, F. E., Bülow, D., Tóth, M., Machwart, K., Brandes, P., Wiedmann, F., Kohlhaas, M., et al. (2025) · Circulation Research · doi:10.1161/circresaha.124.325658 · Cited by 12
Riahi, E. B., Adelborg, K., Pedersen, L. H., Kristensen, S. R., Hansen, A. T., & Sørensen, H. T. (2022) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12668 · Cited by 11
Taha, H., Youssef, G., Omar, R., Din, A. M. K. E., Din, A. A. S. E., & Meshaal, M. S. (2022) · Indian Heart Journal · doi:10.1016/j.ihj.2022.04.006 · Cited by 12
Toma, M. M., BUNGAU, S. G., Ţiţ, D. M., Moisi, M. I., Bustea, C., Vesa, C. M., Behl, T., Stoicescu, M., Brisc, M. C., Purza, A. L., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113002 · Cited by 12
Zhang, S., Cui, Y., Li, J., Tian, H., Yun, Y., Zhou, X., Fang, H., Zhang, H., Zou, C., & Ma, X. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.970847 · Cited by 12
Li, D., Shi, C., Zhao, J., Liu, Y., & Li, C. (2022) · Tsinghua Science & Technology · doi:10.26599/tst.2022.9010008 · Cited by 12
Machino, T., Aonuma, K., Maruo, K., Komatsu, Y., Yamasaki, H., Igarashi, M., Nogami, A., & Ieda, M. (2023) · PLoS ONE · doi:10.1371/journal.pone.0281818 · Cited by 12
Pergola, V., D’Andrea, A., Galzerano, D., Mantovani, F., Rizzo, M., Giannuario, G. D., Khoury, G., Polizzi, V., Rabia, G., Gimelli, A., et al. (2023) · Journal of Cardiovascular Echography · doi:10.4103/jcecho.jcecho_44_23 · Cited by 10
The growing burden of atrial fibrillation and its consequences
Wu, J., & Nadarajah, R. (2024) · BMJ · doi:10.1136/bmj.q826 · Cited by 12
Gue, Y. X., Bloomfield, D., Freedholm, D., & Lip, G. Y. H. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082277 · Cited by 12
Dobry, P., Edwin, S. B., Haymart, B., Barnes, G. D., Kaatz, S., Ali, M. A., & Giuliano, C. A. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2024.08.009 · Cited by 12
Salmela, B., Jaakkola, J., Kalatsova, K., Inkovaara, J., Aro, A. L., Teppo, K., Penttilä, T., Halminen, O., Haukka, J. K., Jukka Putaala, A., et al. (2024) · EP Europace · doi:10.1093/europace/euae264 · Cited by 12
Addressing Cardiovascular Diseases Challenges in South Korea: Strategies to Improve Outcomes
Kang, H., Wang, J., Cho, E. J., Kim, H., Lee, C. J., Park, J. H., Kang, J., Suh, J., Choi, K. H., Lee, S., et al. (2025) · Korean Circulation Journal · doi:10.4070/kcj.2024.0385 · Cited by 13
Schaffer, A. L., Falster, M. O., Brieger, D. B., Jorm, L. R., Wilson, A., Hay, M., Leeb, K., Pearson, S., & Nasis, A. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.014287 · Cited by 12
Lee, E., Lee, S., Choi, E., Han, K., Cha, M., Lip, G. Y. H., & Oh, S. (2020) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14737 · Cited by 12
Hurley, N. C., Spatz, E. S., Krumholz, H. M., Jafari, R., & Mortazavi, B. J. (2020) · ACM Transactions on Computing for Healthcare · doi:10.1145/3417958 · Cited by 13
Kong, M., Hong, Z., Liu, X., Zhu, X., Wang, J., & Dong, A. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd9070224 · Cited by 11
Rivas, E., Sasaki, K., Chen, L., Wang, J., Quintini, C., Maheshwari, K. K., Turan, A., Fares, M. A., & Cywiński, J. B. (2022) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2022.07.013 · Cited by 13
Deficiency of Pdk1 drives heart failure by impairing taurine homeostasis through Slc6a6
Li, C., Zhou, Y., Niu, Y., He, W., Wang, X., Zhang, X., Wu, Y., Zhang, W., Zhao, L., Zheng, H. X., et al. (2023) · The FASEB Journal · doi:10.1096/fj.202300272r · Cited by 12
Niehues, P., Wolfes, J., Wegner, F. K., Ellermann, C., Rath, B., & Eckardt, L. (2023) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2023.11.005 · Cited by 12
Atrial Fibrillation After Gastrointestinal Surgery: Incidence and Associated Risk Factors
Heywood, E. G., Drake, T. M., Bradburn, M. J., Lee, J., Wilson, M., & Lee, M. J. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2019.01.017 · Cited by 12
Imaging for Percutaneous Left Atrial Appendage Closure: A Contemporary Review
Ramchand, J., Harb, S. C., Miyasaka, R., Kanj, M. H., Saliba, W. I., & Jaber, W. A. (2019) · Structural Heart · doi:10.1080/24748706.2019.1643957 · Cited by 12
The role of obesity in the development of atrial fibrillation: current problem status
Podzolkov, V. I., Tarzimanova, A. I., Габдуллович, Г. Р., Арсеновна, О. К., & Lobova, N. V. (2019) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2019-4-109-114 · Cited by 12
Dong, Z., Du, X., Lu, S., Jiang, C., Xia, S., He, L., Su, X., Jia, Z., Long, D., Sang, C., et al. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-01951-5 · Cited by 12
Ritchie, L. A., Oke, O. B., Harrison, S. L., Rodgers, S., Lip, G. Y. H., & Lane, D. A. (2020) · Age and Ageing · doi:10.1093/ageing/afaa268 · Cited by 12
Shen, Z.-X., Sun, Y.-M., Gu, H.-H., Zhang, Y., Shen, Z.-W., Liang, X.-N., Ding, D., & Wang, J. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-02278-x · Cited by 13
Brancato, S. C., Wang, M., Spinelli, K. J., Gandhavadi, M. B., Worrall, N. K., Lehr, E. J., DeBoard, Z., Fitton, T. P., Leiataua, A., Piccini, J. P., et al. (2021) · Heart Rhythm O2 · doi:10.1016/j.hroo.2021.12.003 · Cited by 12
Current Therapeutic Approach to Atrial Fibrillation in Patients with Congenital Hemophilia
Bădescu, M. C., Bădulescu, O. V., Butnariu, L. I., Floria, M., Ciocoiu, M., Costache, I. I., Popescu, D., Bratoiu, I., Buliga-Finiș, O. N., & Rezuș, C. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12040519 · Cited by 12
Raatikainen, M. J. P., Penttilä, T., Korhonen, P. A., Mehtälä, J., Lassila, R., & Lehto, M. (2018) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvy009 · Cited by 12
Magnussen, C., Ojeda, F., Wild, P. S., Sörensen, N. A., Rostock, T., Hoffmann, B. A., Prochaska, J. H., Lackner, K. J., Beutel, M. E., Blettner, M., et al. (2018) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2018.03.028 · Cited by 12
Engler, D., Hanson, C. L., Desteghe, L., Boriani, G., Diederichsen, S. Z., Freedman, B., Palà, E., Potpara, T., Witt, H., Heidbüchel, H., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-059156 · Cited by 11
Aras, D., Birgül, E., Görenek, B., Gürkaş, E., Özdemi̇r, A. Ö., Topçuoğlu, M. A., Yavuz, E., & Zoghi, M. (2022) · The Anatolian Journal of Cardiology · doi:10.5152/anatoljcardiol.2022.1689 · Cited by 11
Waller, A. E., Fakes, K., Carey, M. L., Dizon, J., Parrey, K., Coad, M., & Sanson‐Fisher, R. (2023) · BMC Psychology · doi:10.1186/s40359-023-01068-8 · Cited by 15
Insuficiencia cardiaca en octogenarios con fibrilación auricular: incidencia y factores de riesgo
Melendo‐Viu, M., Raposeiras‐Roubín, S., Abu-Assi, E., Pérez, D. D., Cabeza, M. C., Fernández, S. F., Expósito, L. P., Prieto, S. B., García, E., & Íñiguez, A. (2023) · Revista Española de Cardiología · doi:10.1016/j.recesp.2023.05.002 · Cited by 11
Zhang, A., Li, H., Song, Q., Cui, Y., Zhang, Y., Wang, X., Li, Z., & Hou, Y. (2023) · Lipids in Health and Disease · doi:10.1186/s12944-023-01952-7 · Cited by 11
Liver fibrosis and outcomes of atrial fibrillation: the FIB-4 index
Raposeiras‐Roubín, S., Barcía, J. A. P., Castro, A. L., Caro, V. N., Piñeiro, A. L., Bermúdez, I. G., Ferreiro, R. G., Íñiguez, A., & Abu‐Assi, E. (2023) · Clinical Research in Cardiology · doi:10.1007/s00392-023-02330-0 · Cited by 11
Huang, J., Chan, Y., Tse, Y., Yu, S.-Y., Li, H., Chen, C., Zhao, C., Liu, M., Wu, M., Ren, Q. W., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.032378 · Cited by 11
Huang, W., Sun, H., Xiong, S., Luo, Y., Tang, Y., Zhang, Z., & Liu, H. (2024) · European journal of medical research · doi:10.1186/s40001-024-01952-y · Cited by 11
Mahim, S. M., Hossen, M. E., Hasan, S. A., Islam, M. K., Iqbal, Z., Alibakhshikenari, M., Collotta, M., & Miah, M. S. (2024) · IEEE Access · doi:10.1109/access.2024.3467181 · Cited by 12
GLP ‐1 receptor agonists and cardiovascular events in metabolically healthy or unhealthy obesity
Bucci, T., Alam, U., Fauchier, G., Lochon, L., Bisson, A., Ducluzeau, P., Lip, G. Y. H., & Fauchier, L. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16238 · Cited by 11
Biton, Y., Huang, D. T.-C., Goldenberg, I., Rosero, S. Z., Moss, A. J., Kutyifa, V., McNitt, S. A., Strasberg, B., Zaręba, W., & Barsheshet, A. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.12.032 · Cited by 11
Kany, S., Brachmann, J., Lewalter, T., Kück, K., Andresen, D., Willems, S., Hoffmann, E., Eckardt, L., Thomas, D., Hochadel, M., et al. (2020) · Clinical Research in Cardiology · doi:10.1007/s00392-020-01763-1 · Cited by 11
Lifestyle as a Risk Factor for Atrial Fibrillation
Gallagher, C., Middeldorp, M. E., Hendriks, J., Lau, D. H., & Sanders, P. (2021) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2020.11.013 · Cited by 12
Espnes, H., Ball, J., Løchen, M., Wilsgaard, T., Njølstad, I., Mathiesen, E. B., Gerdts, E., & Sharashova, E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10071514 · Cited by 12
Valenti, A. C., Albini, A., Imberti, J. F., Vitolo, M., Bonini, N., Lattanzi, G., Schnabel, R. B., & Boriani, G. (2022) · Biology · doi:10.3390/biology11040530 · Cited by 11
Researchers of the NONAVASC Study Cardiovascular Risk Group of the Spanish Society of Internal Medicine, Miquélez, A. A., Calleja, M. A. R., Gullón, A., Reino, A. P., Formiga, F., Camafort, M., Rodrigo, J. M. C., Mostaza, J. M., Fernández, C. S., et al. (2020) · The journal of nutrition health & aging · doi:10.1007/s12603-020-1418-0 · Cited by 11
Cao, Y., Liu, X., Xue, Z., Yin, K., Ma, J., Zhu, W., Liu, F., Luo, J., & Sun, J. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.894664 · Cited by 11
Vio, R., Giordani, A. S., Stefil, M., Madine, J., Fairbairn, T. A., Themistoclakis, S., Salvi, P., Caforio, A. L. P., Shantsila, A., Shantsila, E., et al. (2022) · Journal of Hypertension · doi:10.1097/hjh.0000000000003223 · Cited by 11
Visit-to-visit SBP variability and risk of atrial fibrillation in middle-aged and older populations
Wang, C., Sun, Y., Qian, X., Han, X., Cai, Z., Zhao, M., Yun, C., Zhang, S., Hou, Z., Chen, S., et al. (2022) · Journal of Hypertension · doi:10.1097/hjh.0000000000003291 · Cited by 11
Promising Therapies for Atrial Fibrillation and Ventricular Tachycardia
Mircea, A. A., Rusu, M., Liehn, E. A., & Bucur, O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012612 · Cited by 11
Tomsits, P., Volz, L.-S., Xia, R., Chivukula, A. S., Schüttler, D., & Clauß, S. (2023) · Lab Animal · doi:10.1038/s41684-023-01141-0 · Cited by 11
Liu, X., Wu, M., He, Y., Gui, C., Weiming, W., Jiang, Z., & Zhong, G. (2023) · Scientific Reports · doi:10.1038/s41598-023-34851-z · Cited by 11
Shroff, G. R., Solid, C. A., Bloomgarden, Z. T., Halperin, J. L., & Herzog, C. A. (2016) · Journal of Diabetes · doi:10.1111/1753-0407.12392 · Cited by 11
Méndez‐Bailón, M., Muñoz‐Rivas, N., Jiménez‐García, R., Hernández‐Barrera, V., de Miguel-Yanes, J. M., Villalba, N. L., de Miguel‐Díez, J., & López‐de‐Andrés, A. (2017) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2017.05.008 · Cited by 11
Pathway for the Management of Atrial Fibrillation and Atrial Flutter
Herzog, E., Argulian, E., Levy, S. B., & Aziz, E. F. (2017) · Critical Pathways in Cardiology A Journal of Evidence-Based Medicine · doi:10.1097/hpc.0000000000000109 · Cited by 11
The incidence of atrial fibrillation and the added value of thumb ECG for detecting new cases
Mandalenakis, Z., Lennartsson, S. T., Fu, M. L. X., Lappas, G., Li, S., Rosengren, A., Dellborg, M., Thunström, E. Ö., Caidahl, K., & Hansson, P. (2018) · Scandinavian Cardiovascular Journal · doi:10.1080/14017431.2018.1509120 · Cited by 11
Falissard, B., Picard, F. A., Mahé, I., Hanon, O., Touzé, E., Danchin, N., Lamy, F.-X., Ricci, L., & Steg, P. G. (2019) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2019.02.003 · Cited by 11
Mortality in young adult patients with acute ischaemic stroke
Schneider, S., Vibo, R., Taba, N., & Kõrv, J. (2019) · Acta Neurologica Scandinavica · doi:10.1111/ane.13217 · Cited by 11
Dhaliwal, K. K., Upadhya, B., Soliman, E. Z., Beaty, E., Yeboah, J., Bhave, P. D., Whalen, S. P., & Singleton, M. J. (2020) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2020.05.009 · Cited by 11
Dinesen, B., Gade, J. D., Schacksen, C. S., Spindler, H., Albertsen, A. E., Dittmann, L., Jochumsen, M., & Møller, D. S. (2021) · JMIR Cardio · doi:10.2196/27321 · Cited by 10
Association between KCNE1 G38S gene polymorphism and risk of atrial fibrillation
Jiang, Y., Chen, M., Zhang, N., Yang, H.-J., Xu, L.-B., Rui, Q., Sun, S.-J., Yao, J.-L., & Zhou, Y. (2017) · Medicine · doi:10.1097/md.0000000000007253 · Cited by 11
Alhede, C., Lauridsen, T. K., Johannessen, A. C., Dixen, U., Jensen, J. S., Raatikainen, P. M. J., Hindricks, G., Walfridsson, H., Kongstad, O., Pehrson, S. M., et al. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.09.208 · Cited by 11
Ward-Caviness, C. K. (2021) · Circulation · doi:10.1161/circulationaha.121.057533 · Cited by 11
Prevention of atrial fibrillation: a call to action
Elliott, A. D., Benjamin, E. J., & Middeldorp, M. E. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad738 · Cited by 11
Choi, S. Y., Kim, M. H., Kim, H. T., Kang, S., Lee, K., Hyun, K., & Yun, S. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11071823 · Cited by 10
RetractedGenetic Basis of Early Onset Atrial Fibrillation in Patients without Risk Factors
Rudaka, I., Vilne, B., Isakova, J., Kalējs, O., Gailīte, L., & Rots, D. (2023) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd10030104 · Cited by 10
Papp, T., Kiss, Z., Rokszin, G., Fábián, I., Márk, L., Bagoly, Z., Becker, D. A., Merkely, B. P., Aradi, D., Dézsi, C. A., et al. (2023) · Clinical Therapeutics · doi:10.1016/j.clinthera.2023.03.008 · Cited by 11
Does asymptomatic atrial fibrillation exist?
Carneiro, H. A., & Knight, B. P. (2023) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.16108 · Cited by 11
Park, H., Kim, D., Jang, E., Yu, H. T., Kim, T., Kim, D., Sung, J., Pak, H., Lee, M., Lip, G. Y. H., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03400-4 · Cited by 10
Noubiap, J. J., Pathak, R. K., Thomas, G., Elliott, A. D., Sanders, P., & Middeldorp, M. E. (2024) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.123.012534 · Cited by 10
Geschlechterspezifische Aspekte kardiovaskulärer Erkrankungen
Baessler, A., Bauer, P., Becker, M., Berrisch-Rahmel, S., Goldmann, B. U., Grünig, E., Hamm, C., Meder, B., Kindermann, I., Ong, P., et al. (2024) · Die Kardiologie · doi:10.1007/s12181-024-00694-9 · Cited by 11
Osorio, J., Hincapie, D., Varley, A. L., Silverstein, J. R., Matos, C. D., Thosani, A. J., Thorne, C., D'Souza, B. A., Alviz, I., Gabr, M., et al. (2024) · Heart Rhythm · doi:10.1016/j.hrthm.2024.07.094 · Cited by 10
Yu, X., Chao, J., Wang, X., Dun, S., Song, H., Guo, Y., Zhang, H., Yao, Y., Liu, Z., Wang, J., et al. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.03.001 · Cited by 11
Atrial Fibrillation Ablation: Impact on Burden and Cardiovascular Outcomes
AlTurki, A., & Essebag, V. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082648 · Cited by 10
Amin, A. M., Turkmani, M. M., Barznji, S. A., Mohanty, S., Kaplan, R. M., Winterfield, J. R., Lakkireddy, D., Santangeli, P., Biase, L. D., & Natale, A. (2025) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.16728 · Cited by 12
Bonnet, F., Vaduva, P., Balkau, B., Genet, T., de Fréminville, J.-B., Ducluzeau, P., & Fauchier, L. (2025) · European Journal of Endocrinology · doi:10.1093/ejendo/lvaf183 · Cited by 10
MRI use for atrial tissue characterization in arrhythmias and for EP procedure guidance
Schmidt, E. J., & Halperin, H. R. (2017) · International journal of cardiac imaging · doi:10.1007/s10554-017-1179-y · Cited by 10
Burden of arrhythmia in hospitalizations with opioid overdose
Doshi, R. P., Shah, J., Desai, R., & Gullapalli, N. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.01.047 · Cited by 10
Fukuhara, E., Mine, T., Kishima, H., & Ishihara, M. (2020) · Heart and Vessels · doi:10.1007/s00380-020-01702-0 · Cited by 10
Sex differences in the Norwegian Tenecteplase Trial (NOR‐TEST)
Ihle‐Hansen, H., Sandset, E. C., Ihle‐Hansen, H., Hagberg, G., Thommessen, B., Rønning, O. M., Kvistad, C. E., Novotný, V., Næss, H., Waje‐Andreassen, U., et al. (2021) · European Journal of Neurology · doi:10.1111/ene.15126 · Cited by 10
Paroxysmal atrial fibrillation
Gahungu, N., Trueick, R., Coopes, M., & Gabbay, E. (2021) · BMJ · doi:10.1136/bmj-2021-058568 · Cited by 10
Magdi, M., Renjithal, S. L. M., Mubasher, M., Mostafa, M. R., Lathwal, Y., Mukuntharaj, P., Mohamed, S., Alweis, R. L., Tan, B. E., & Baibhav, B. (2021) · PubMed Central · Cited by 10
Yoshimoto, T., Toyoda, K., Ihara, M., Inoue, H., Yamashita, T., Suzuki, S., Akao, M., Atarashi, H., Ikeda, T., Okumura, K., et al. (2022) · Stroke · doi:10.1161/strokeaha.121.038285 · Cited by 10
Li, Y., Song, J., Wu, B., Wang, X., Lin, H., & Han, Z. (2022) · European journal of medical research · doi:10.1186/s40001-022-00738-4 · Cited by 10
Metadata
- Authors
- Schnabel, R. B., Yin, X., Gona, P., Larson, M. G., Beiser, A. S., McManus, D. D., Newton-Cheh, C., Lubitz, S. A., Magnani, J. W., Ellinor, P. T., Seshadri, S., Wolf, P. A., Vasan, R. S., Benjamin, E. J., & Levy, D.
- Affiliations
- Framingham Heart Study (US)
- Boston University (US)
- University of Massachusetts Chan Medical School (US)
- Harvard University (US)
- Broad Institute (US)
- Corresponding author
- Schnabel, Renate B
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 386
- Issue
- 9989
- Pages
- 154-162
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- PMC
- PMC4553037
- OpenAlex
- W1924098982
- Cited by
- 1,746
- References
- 32
- Citations by year
- 2026: 126 · 2025: 209 · 2024: 253 · 2023: 192 · 2022: 198 · 2021: 155 · 2020: 145 · 2019: 141 · 2018: 120 · 2017: 110 · 2016: 76 · 2015: 20
- FWCI
- 79.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion)
- Funders
- NIH/NHLBI (contract N01-HC-25195, grant 1K23HL114724)
- NIH (grants 1RC1HL101056, HL102214, and AG028321, grant 2R01HL092577, grants 1U01HL105268-01 and KL2RR031981)
- Fondation Leducq (14CVD01) and NIH grants (1R01HL092577, 1RC1HL101056, 1R01HL102214, 1R01AG028321, R01HL104156, and 1K24HL105780)
- American Heart Association Established Investigator Award (13EIA14220013)
- Deutsche Forschungsgemeinschaft (German Research Foundation) Emmy Noether Program (SCHN 1149/3-2)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- atrial fibrillation, prevalence trends, incidence trends, sex differences, risk factors, stroke, mortality, Framingham Heart Study, electrocardiogram screening, atrial fibrillation screening, atrial fibrillation prevention, cardiovascular disease prevention, long-term cohort follow-up
- MeSH terms
- Aged, Aged, 80 and over, Atrial Fibrillation, Electrocardiography, Female, Humans, Male, Middle Aged, Mortality, Risk Factors, United States, Cohort Studies, Incidence, Prevalence, Age Distribution, Sex Distribution, Stroke
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
