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Role of αv integrins on perivascular mesenchymal cells in regulation of skeletal and cardiac muscle fibrosis
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ITGAV has been identified as a key regulator of fibrosis, playing a role in both cardiac and liver fibrosis.
“ITGAV has also been identified as a key regulator of fibrosis, playing a role in both cardiac and liver fibrosis [50,51]”
From Identifying novel drug targets for calcific aortic valve disease through Mendelian randomization (2025) · cites this paper as [50]
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Identifying novel drug targets for calcific aortic valve disease through Mendelian randomization
Xu, D., Lu, J., Yang, Y., Hu, W., Chen, J., Xue, J., Yang, S., Cao, N., Hu, H., Qian, N., et al. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119110 · Cited by 10
Metadata
- Authors
- Murray, I., Gonzalez, Z., Baily, J., Smith, J., Thomson, A., Greenhalgh, S., Dobbie, R., Kendall, T., Gray, G., Griggs, D., Ruminski, P., Simpson, H., Iredale, J., Peault, B., & Henderson, N.
- Affiliations
- University of Edinburgh (GB)
- Saint Louis University (US)
- Corresponding author
- Murray, Iain
- ORCID
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 389
- Pages
- S13
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2590575146
- Cited by
- 1
- References
- 0
- Citations by year
- 2025: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Lancet (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Keywords
- ITGAV, muscle fibrosis, skeletal muscle fibrosis, myocardial fibrosis, PDGFRβ, myofibroblasts, cardiotoxin-induced muscle injury, angiotensin II, fibrosis treatment
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