Cited by 223Dermatological diseases and infestationsParasitic Diseases Research and TreatmentParasites and Host Interactions

The public health control of scabies: priorities for research and action.

Open access
Engelman, Daniel, Cantey, Paul T, Marks, Michael, Solomon, Anthony W, Chang, Aileen Y, Chosidow, Olivier, Enbiale, Wendemagegn, Engels, Dirk +16 more·2019·The Lancet

Abstract

Scabies is a parasitic disease of the skin that disproportionately affects disadvantaged populations. The disease causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease. Scientific advances from the past 5 years suggest that scabies is amenable to population-level control, particularly through mass drug administration. In recognition of these issues, WHO added scabies to the list of neglected tropical diseases in 2017. To develop a global control programme, key operational research questions must now be addressed. Standardised approaches to diagnosis and methods for mapping are required to further understand the burden of disease. The safety of treatments for young children, including with ivermectin and moxidectin, should be investigated. Studies are needed to inform optimum implementation of mass treatment, including the threshold for intervention, target, dosing, and frequency. Frameworks for surveillance, monitoring, and evaluation of control strategies are also necessary.

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Crossref · 10.1016/s0140-6736(19)31136-5

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  • Scabies among adults frequently is sexually acquired, although scabies among children usually is not.

    “Scabies among adults frequently is sexually acquired, although scabies among children usually is not (1400–1402).”

    From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1401]

    The burden of scabies section says transmission requires skin-to-skin contact, but does not say how often adults acquire scabies sexually or compare sexual acquisition in adults and children. Searches for sexual acquisition and sexual contact found no passage in our copy addressing that distinction. (LLM, conf=0.76)

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Research works printed but not linked: 6

  1. [62]Banerji A. Scabies. Paediatr Child Health 2015; 20: 395– 402. 26527041 PMC4614097
  2. [100]Johnstone P, Strong M. Scabies. BMJ Clin Evid 2014; 2014: 1707. PMC4278180 25544114
  3. [133]WHO. Alternative mass drug administration regimens to eliminate lymphatic filariasis. Geneva: World Health Organization, 2017. 29565523
  4. [152]Thean LJ, Engelman D, Kaldor J, Steer AC. Scabies: new opportunities for management and population control. Pediatr Infect Dis J 2019; 38: 211– 13. 30299425
  5. [157]Martin D, Wiegand R, Goodhew B, Lammie P, Mkocha H, Kasubi M. Impact of ivermectin mass drug administration for lymphatic filariasis on scabies in eight villages in Kongwa District, Tanzania. Am J Trop Med Hyg 2018; 99: 937– 39. 30062986 PMC6159570
  6. [159]Romani L, Kaldor J, Steer A. Sustained reduction of scabies two years after mass drug administration. N Engl J Med (in press).

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Authors
Engelman, D., Cantey, P. T., Marks, M., Solomon, A. W., Chang, A. Y., Chosidow, O., Enbiale, W., Engels, D., Hay, R. J., Hendrickx, D., Hotez, P. J., Kaldor, J. M., Kama, M., Mackenzie, C. D., McCarthy, J. S., Martin, D. L., Mengistu, B., Maurer, T., Negussu, N., Romani, L., Sokana, O., Whitfeld, M. J., Fuller, L. C., & Steer, A. C.
Affiliations
  • Royal Children's Hospital (AU)
  • World Health Organization (CH)
  • London School of Hygiene & Tropical Medicine (GB)
  • University of California, San Francisco (US)
  • Université Paris-Est Créteil (FR)
  • Bahir Dar University (ET)
  • King's College London (GB)
  • The Kids Research Institute Australia (AU)
  • Baylor College of Medicine (US)
  • UNSW Sydney (AU)
  • Ministry Of Health (FJ)
  • The Task Force for Global Health (US)
  • QIMR Berghofer Medical Research Institute (AU)
  • Centers for Disease Control and Prevention (US)
  • Federal Ministry of Health (ET)
  • National Health Service (GB)
Corresponding author
Engelman, Daniel
Venue
The Lancet
Publisher
Elsevier BV
Published
2019-07
Volume
394
Issue
10192
Pages
81-92
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2948825612
Cited by
223
References
158
Citations by year
2026: 35 · 2025: 32 · 2024: 43 · 2023: 28 · 2022: 27 · 2021: 26 · 2020: 27 · 2019: 5
FWCI
2.98
Type
journal article
Language
en
Locations
  • The Lancet (publishedVersion)
  • UWA Profiles and Research Repository (UWA) (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
  • UNSWorks (University of New South Wales, Sydney, Australia) (submittedVersion, cc-by-nc-nd)
  • Research Portal (King's College London) (submittedVersion)
Funders
  • National Heart Foundation of Australia
  • American Chemical Society
  • National Health Research Institutes
  • National Health and Medical Research Council
Topics
  • Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
  • Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
  • Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
Keywords
scabies, public health control, mass drug administration, neglected tropical diseases, ivermectin, moxidectin, diagnosis, surveillance and monitoring
MeSH terms
Mass Drug Administration, Humans, Population Surveillance, Public Health, Scabies, Global Health, World Health Organization, Neglected Diseases

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