MORTALITY AND MORBIDITY RESULTS FROM THE EUROPEAN WORKING PARTY ON HIGH BLOOD PRESSURE IN THE ELDERLY TRIAL*1, *2

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults

Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.006 · Cited by 6,616

2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)

Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655

Blood pressure, stroke, and coronary heart disease

Collins, R., Peto, R., MacMahon, S., Godwin, J., Qizilbash, N., Collins, R., MacMahon, S., Hebert, P., Eberlein, K. A., Taylor, J. O., et al. (1990) · The Lancet · doi:10.1016/0140-6736(90)90944-z · Cited by 4,491

Treatment of hypertension in patients 80 years of age or older

Beckett, N. S., Peters, R., Fletcher, A. E., Staessen, J. A., Liu, L., Dumitrascu, D., Stoyanovsky, V., Antikainen, R. L., Nikitin, Y., Anderson, C., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801369 · Cited by 3,092

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

Staessen, J. A., Fagard, R., Thijs, L., Celis, H., Arabidze, G. G., Birkenhäger, W. H., Bulpitt, C. J., de Leeuw, P. W., Dollery, C. T., Fletcher, A. E., et al. (1997) · The Lancet · doi:10.1016/s0140-6736(97)05381-6 · Cited by 2,989

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

Mancia, G., Laurent, S., Agabiti-Rosei, E., Ambrosioni, E., Burnier, M., Caulfield, M. J., Cifkova, R., Clément, D., Coca, A., Dominiczak, A., et al. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e328333146d · Cited by 1,643

Prevention of coronary heart disease in clinical practice Recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention

Second Joint Task Force of European (1998) · European Heart Journal · doi:10.1053/euhj.1998.1243 · Cited by 1,131

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000596 · Cited by 1,127

Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis

Webb, A. J., Fischer, U., Mehta, Z., & Rothwell, P. M. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60235-8 · Cited by 729

The Exclusion of the Elderly and Women From Clinical Trials in Acute Myocardial Infarction

Gurwitz, J. H. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03490110055029 · Cited by 532

Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial

Poole-Wilson, P. A., Lubsen, J., Kirwan, B.-A., van Dalen, F. J., Wagener, G., Danchin, N., Just, H., Fox, K. A., Pocock, S. J., Clayton, T. C., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16980-8 · Cited by 511

Comparative Antihypertensive Effects of Hydrochlorothiazide and Chlorthalidone on Ambulatory and Office Blood Pressure

Ernst, M. E., Carter, B. L., Goerdt, C. J., Steffensmeier, J. J. G., Phillips, B. B., Zimmerman, M. B., & Bergus, G. R. (2006) · Hypertension · doi:10.1161/01.hyp.0000203309.07140.d3 · Cited by 433

Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

Thomopoulos, C., Parati, G., & Zanchetti, A. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000378 · Cited by 388

Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

Brunström, M., & Carlberg, B. (2016) · BMJ · doi:10.1136/bmj.i717 · Cited by 375

Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes

Kostis, J. B., Wilson, A. C., Freudenberger, R. S., Cosgrove, N. M., Pressel, S. L., & Davis, B. R. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.08.059 · Cited by 325

Elevated systolic blood pressure and risk of cardiovascular and renal disease: overview of evidence from observational epidemiologic studies and randomized controlled trials

He, J., & Whelton, P. K. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70312-1 · Cited by 325

Effects of blood pressure lowering on outcome incidence in hypertension: 7. Effects of more vs. less intensive blood pressure lowering and different achieved blood pressure levels – updated overview and meta-analyses of randomized trials

Thomopoulos, C., Parati, G., & Zanchetti, A. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000000881 · Cited by 298

Benefits of cardiac rehabilitation and exercise training in secondary coronary prevention in the elderly

Lavie, C. J., Milani, R. V., & Littman, A. B. (1993) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(93)90176-2 · Cited by 267

Effects of blood-pressure-lowering treatment on outcome incidence in hypertension: 10 – Should blood pressure management differ in hypertensive patients with and without diabetes mellitus? Overview and meta-analyses of randomized trials

Thomopoulos, C., Parati, G., & Zanchetti, A. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001276 · Cited by 206

Cardiovascular drug therapy in the elderly: benefits and challenges

Fleg, J. L., Aronow, W. S., & Frishman, W. H. (2011) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2010.162 · Cited by 186

Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials

Bejan-Angoulvant, T., Saadatian-Elahi, M., Wright, J. M., Schron, E. B., Lindholm, L. H., Fagard, R., Staessen, J. A., & Gueyffier, F. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e328339f9c5 · Cited by 178

Diuretics for Hypertension: A Review and Update

Roush, G. C., & Sica, D. A. (2016) · American Journal of Hypertension · doi:10.1093/ajh/hpw030 · Cited by 142

Blood pressure is linked to salt intake and modulated by the angiotensinogen gene in normotensive and hypertensive elderly subjects

Johnson, A. G., Nguyen, T. V., & Davis, D. (2001) · Journal of Hypertension · doi:10.1097/00004872-200106000-00009 · Cited by 126

Nonpharmacologic Intervention to Reduce Blood Pressure in Older Patients With Mild Hypertension

Applegate, W. B., Miller, S. T., Elam, J. T., Cushman, W. C., El Derwi, D., Brewer, A., & Graney, M. J. (1992) · Archives of Internal Medicine · doi:10.1001/archinte.1992.00400180034005 · Cited by 106

The Study on COgnition and Prognosis in the Elderly (SCOPE); outcomes in patients not receiving add-on therapy after randomization

Lithell, H., Hansson, L., Skoog, I., Elmfeldt, D., Hofman, A., Olofsson, B., Trenkwalder, P., & Zanchetti, A. (2004) · Journal of Hypertension · doi:10.1097/01.hjh.0000133730.47372.4c · Cited by 104

Effects of intensive blood pressure lowering on mortality and cardiovascular and renal outcomes in type 2 diabetic patients: A meta-analysis

Wang, J., Chen, Y., Xu, W., Lu, N., Cao, J., & Yu, S. (2019) · PLOS ONE · doi:10.1371/journal.pone.0215362 · Cited by 45

Identification of Risk Factors in Hypertensive Patients: Contribution of Randomized Controlled Trials Through an Individual Patient Database

Gueyffier, F., Boissel, J.-P., Pocock, S., Boutitie, F., Coope, J., Cutler, J., Ekbom, T., Fagard, R., Friedman, L., Kerlikowske, K., et al. (1999) · Circulation · doi:10.1161/01.cir.100.18.e88 · Cited by 46

Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Aparicio, L. S., Thijs, L., Boggia, J., Jacobs, L., Barochiner, J., Odili, A. N., Alfie, J., Asayama, K., Cuffaro, P. E., Nomura, K., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05800 · Cited by 45

Efficacy and safety of two treatment combinations of hypertension in very elderly patients

Fogari, R., Zoppi, A., Mugellini, A., Corradi, L., Lazzari, P., Preti, P., & Derosa, G. (2009) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2008.03.012 · Cited by 33

Evidence-based Diuretics: Focus On Chlorthalidone and Indapamide

DiNicolantonio, J. J., Bhutani, J., Lavie, C. J., & O’Keefe, J. H. (2015) · Future Cardiology · doi:10.2217/fca.14.83 · Cited by 29