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IMPACT OF VITAMIN A SUPPLEMENTATION ON CHILDHOOD MORTALITY

Open access
Sommer, Alfred, Djunaedi, Edi, Loeden, A.A, Tarwotjo, Ignatius, West, KeithP, Tilden, Robert, Mele, Lisa, The Aceh Study Group·1986·The Lancet

Abstract

450 villages in northern Sumatra were randomly assigned to either participate in a vitamin A supplementation scheme (n = 229) or serve for 1 year as a control (n = 221). 25 939 preschool children were examined at baseline and again 11 to 13 months later. Capsules containing 200 000 IU vitamin A were distributed to preschool children aged over 1 year by local volunteers 1 to 3 months after baseline enumeration and again 6 months later. Among children aged 12-71 months at baseline, mortality in control villages (75/10 231, 7.3 per 1000) was 49% greater than in those where supplements were given (53/10 919, 4.9 per 1000) (p less than 0.05). The impact of vitamin A supplementation seemed to be greater in boys than in girls. These results support earlier observations linking mild vitamin A deficiency to increased mortality and suggest that supplements given to vitamin A deficient populations may decrease mortality by as much as 34%.

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Metadata

Authors
Sommer, A., Djunaedi, E., Loeden, A. A., Tarwotjo, I., West, K., Tilden, R., Mele, L., & The Aceh Study Group
Venue
The Lancet
Publisher
Elsevier BV
Published
1986-05
Volume
327
Issue
8491
Pages
1169-1173
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2140409429
Cited by
680
References
0
FWCI
23.14
Type
journal article
Language
en
Open access
hybrid

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