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Mindfulness-based stress reduction and health-related quality of life in a heterogeneous patient population
Open accessAbstract
This study examined the effects of mindfulness-based stress reduction (MBSR) on health-related quality of life and physical and psychological symptomatology in a heterogeneous patient population. Patients (n=136) participated in an 8-week MBSR program and were required to practice 20 min of meditation daily. Pre- and post-intervention data were collected by using the Short-Form Health Survey (SF-36), Medical Symptom Checklist (MSCL) and Symptom Checklist-90 Revised (SCL-90-R). Health-related quality of life was enhanced as demonstrated by improvement on all indices of the SF-36, including vitality, bodily pain, role limitations caused by physical health, and social functioning (all P<.01). Alleviation of physical symptoms was revealed by a 28% reduction on the MSCL (P<.0001). Decreased psychological distress was indicated on the SCL-90-R by a 38% reduction on the Global Severity Index, a 44% reduction on the anxiety subscale, and a 34% reduction on the depression subscale (all P<.0001). One-year follow-up revealed maintenance of initial improvements on several outcome parameters. We conclude that a group mindfulness meditation training program can enhance functional status and well-being and reduce physical symptoms and psychological distress in a heterogeneous patient population and that the intervention may have long-term beneficial effects.
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“subjective quality of life (Reibel et al., 2001; Shapiro et al., 2005; Nyklícek and Kuijpers, 2008; Fang et al., 2010)”
From Mindfulness Training Alters Emotional Memory Recall Compared to Active Controls: Support for an Emotional Information Processing Model of Mindfulness (2012) · cites this paper as Reibel et al., 2001
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“The 2/3 response rate, however, is comparable to open trials in similar academic medical settings [43–45].”
From Mindfulness Meditation Targets Transdiagnostic Symptoms Implicated in Stress-Related Disorders: Understanding Relationships between Changes in Mindfulness, Sleep Quality, and Physical Symptoms (2018) · cites this paper as [45]
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“According to Bishop [3], randomized clinical trials confirmed the positive effect of meditation and provide encouraging results with patients showing a significant reduction in psychological morbidity associated with mental illness [47–49] and a decrease in stress level, resulting in increased emotional well-being.”
From Mindful emotion regulation: Exploring the neurocognitive mechanisms behind mindfulness (2015) · cites this paper as [48]
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Metadata
- Authors
- Reibel, D. K., Greeson, J. M., Brainard, G. C., & Rosenzweig, S.
- Affiliations
- Thomas Jefferson University (US)
- Corresponding author
- Reibel, Diane K
- Venue
- General Hospital Psychiatry
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 23
- Issue
- 4
- Pages
- 183-192
- ISSN
- 0163-8343 (ISSN-L)
- OpenAlex
- W2141953156
- Cited by
- 431
- References
- 38
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 10 · 2023: 13 · 2022: 6 · 2021: 13 · 2020: 14 · 2019: 25 · 2018: 25 · 2017: 13 · 2016: 18 · 2015: 24 · 2014: 27 · 2013: 28 · 2012: 19
- FWCI
- 12.66
- Type
- journal article
- Language
- en
- Open access
- green
- jdc.jefferson.edu
- Locations
- General Hospital Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- The Medicine Forum (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Keywords
- mindfulness-based stress reduction, mindfulness meditation, health-related quality of life, somatic symptoms, psychological distress, anxiety, depression, symptom maintenance, heterogeneous patient populations, group intervention, well-being
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Patient Compliance, Population Surveillance, Prospective Studies, Psychotherapy, Quality of Life, Stress, Psychological, Health Behavior, Meditation
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