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Mindfulness-based stress reduction and health-related quality of life in a heterogeneous patient population
Open accessAbstract
This study examined the effects of mindfulness-based stress reduction (MBSR) on health-related quality of life and physical and psychological symptomatology in a heterogeneous patient population. Patients (n=136) participated in an 8-week MBSR program and were required to practice 20 min of meditation daily. Pre- and post-intervention data were collected by using the Short-Form Health Survey (SF-36), Medical Symptom Checklist (MSCL) and Symptom Checklist-90 Revised (SCL-90-R). Health-related quality of life was enhanced as demonstrated by improvement on all indices of the SF-36, including vitality, bodily pain, role limitations caused by physical health, and social functioning (all P<.01). Alleviation of physical symptoms was revealed by a 28% reduction on the MSCL (P<.0001). Decreased psychological distress was indicated on the SCL-90-R by a 38% reduction on the Global Severity Index, a 44% reduction on the anxiety subscale, and a 34% reduction on the depression subscale (all P<.0001). One-year follow-up revealed maintenance of initial improvements on several outcome parameters. We conclude that a group mindfulness meditation training program can enhance functional status and well-being and reduce physical symptoms and psychological distress in a heterogeneous patient population and that the intervention may have long-term beneficial effects.
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“subjective quality of life (Reibel et al., 2001; Shapiro et al., 2005; Nyklícek and Kuijpers, 2008; Fang et al., 2010)”
From Mindfulness Training Alters Emotional Memory Recall Compared to Active Controls: Support for an Emotional Information Processing Model of Mindfulness (2012) · cites this paper as Reibel et al., 2001
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“The 2/3 response rate, however, is comparable to open trials in similar academic medical settings [43–45].”
From Mindfulness Meditation Targets Transdiagnostic Symptoms Implicated in Stress-Related Disorders: Understanding Relationships between Changes in Mindfulness, Sleep Quality, and Physical Symptoms (2018) · cites this paper as [45]
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“According to Bishop [3], randomized clinical trials confirmed the positive effect of meditation and provide encouraging results with patients showing a significant reduction in psychological morbidity associated with mental illness [47–49] and a decrease in stress level, resulting in increased emotional well-being.”
From Mindful emotion regulation: Exploring the neurocognitive mechanisms behind mindfulness (2015) · cites this paper as [48]
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“Reibel, Greeson, Brainard, and Rosenzweig [124] examined the effect of an open enrollment MBSR program on healthrelated quality of life, medical symptoms, and psychological symptoms within a large (N = 136) heterogeneous patient population.”
BackgroundEffects of Mindfulness on Conceptual Modeling Performance: A Series of Experiments
Bernárdez, B., Durán, A., Parejo, J. A., Juristo, N., & Ruiz–Cortés, A. (2020) · IEEE Transactions on Software Engineering · doi:10.1109/tse.2020.2991699 · Cited by 27
Coping resources in individuals with aphasia
DuBay, M. F., Laures-Gore, J. S., Matheny, K., & Romski, M. A. (2011) · Aphasiology · doi:10.1080/02687038.2011.570933 · Cited by 27
Keng, S., Looi, P. S., Tan, E. L. Y., Yim, O. S., Lai, P. S., Chew, S. H., & Ebstein, R. P. (2020) · Behavior Therapy · doi:10.1016/j.beth.2020.01.005 · Cited by 26
A Program in Contemplative Self‐Healing
Loizzo, J. J., Charlson, M. E., & Peterson, J. C. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04398.x · Cited by 26
A controlled experiment to evaluate the effects of mindfulness in software engineering
Bernárdez, B., Durán, A., Parejo, J. A., & Ruiz-Cortés, A. (2014) · International Symposium on Empirical Software Engineering and Measurement · doi:10.1145/2652524.2652539 · Cited by 27
“In [23], neuro–psychologists studied the effects of mindfulness in 136 heterogeneous patients showing that, after two months of daily 20–minute practice, a significant percentage experienced better personal well–being in terms of mental clarity, equanimity, wisdom and self–compassion based on standard health surveys (…”
BackgroundSebri, V., Pizzoli, S. F. M., Marzorati, C., Mazzocco, K., & Pravettoni, G. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1394355 · Cited by 26
Feasibility of a Mindfulness-Based Intervention for Aboriginal Adults with Type 2 Diabetes
Dreger, L. C., Mackenzie, C. S., & McLeod, B. (2013) · Mindfulness · doi:10.1007/s12671-013-0257-z · Cited by 24
Jedel, S., Merriman, P., Hoffman, A., Swanson, B. A., Fogg, L., & Keshavarzian, A. (2012) · Mindfulness · doi:10.1007/s12671-012-0128-z · Cited by 26
Mindfulness Based Stress Reduction: effect on emotional distress in diabetes
Young, L., Cappola, A., & Baime, M. J. (2009) · Practical Diabetes · doi:10.1002/pdi.1380 · Cited by 25
Campbell, R., Soenens, B., Weinstein, N., & Vansteenkiste, M. (2018) · Mindfulness · doi:10.1007/s12671-017-0848-1 · Cited by 28
Tong, X., Gromala, D., Choo, A., Amin, A., & Shaw, C. (2015) · Lecture notes in computer science · doi:10.1007/978-3-319-21067-4_40 · Cited by 26
“Furthermore, analgesics such as opioids can have serious side effects, such as both dependency and addictive tendencies [4, 5].”
BackgroundRaja-Khan, N. T., Agito, K., Shah, J., Stetter, C., Gustafson, T. S., Socolow, H., Kunselman, A. R., Reibel, D. K., & Legro, R. S. (2015) · Contemporary Clinical Trials · doi:10.1016/j.cct.2015.01.021 · Cited by 28
“MBSR has been shown to reduce psychological distress and improve quality of life in various patient populations [30-33].”
BackgroundMethodSelf-citationMartín-Asuero, A., & de la Banda, G. G. (2007) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 23
AN EXAMINATION OF THE RELATIONSHIP BETWEEN QIGONG MEDITATION AND PERSONALITY
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Opening the Contemplative Mind in the Sociology Classroom
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“When utilized, however, the practicality of mindfulness in higher education is often evaluated by quantitative tools such as behavioral tasks or observations in controlled laboratory settings through clinical, psychological, behavioral, or neurological measures (e.g., Randolph et al. 1999; Reibel et al. 2001; Williams…”
BackgroundMethodShook, N. J., Delaney, R. K., Strough, J., Wilson, J. M., Sevi, B., & Altman, N. (2019) · Current Psychology · doi:10.1007/s12144-019-0137-3 · Cited by 26
“Mindfulness-based stress reduction is also associated with decreases in a number of physical complaints, such as insomnia (Gross et al. 2011), pain (Reibel et al. 2001), and irritable bowel (Zernicke et al. 2013).”
BackgroundHassed, C. S., Gullone, E., McNab, C., & Meadows, G. N. (2006) · Cited by 22
Shi, L., WELSH, R. S., Lopes, S. S., Rennert, L., Chen, L., Jones, K. O., Zhang, L., Crenshaw, B., Wilson, M., & Zinzow, H. M. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.03.009 · Cited by 23
Discomfort with emotion moderates distress reduction in a brief mindfulness intervention.
Sass, S. M., Berenbaum, H., & Abrams, E. M. (2013) · International Journal of Behavioral Consultation and Therapy · doi:10.1037/h0100962 · Cited by 21
Bernárdez, B., Durán, A., Parejo, J. A., & Ruiz–Cortés, A. (2016) · Journal of Systems and Software · doi:10.1016/j.jss.2016.06.104 · Cited by 20
Newberg, A. B., Wintering, N., Yaden, D. B., Zhong, L., Bowen, B., Averick, N., & Monti, D. (2017) · Religion Brain & Behavior · doi:10.1080/2153599x.2016.1267035 · Cited by 26
“A large study of a heterogeneous population of patients including those with cancer, HIV, musculoskeletal disorders, pain syndromes, anxiety, and depression showed a 34% reduction in the depression subscale of the Global Severity Index (Reibel et al., 2001).”
BackgroundAdapting Mindfulness to Engage Latinos and Improve Mental Health in Primary Care: a Pilot Study
Ortiz, J. A., Smith, B. W., Shelley, B. M., & Erickson, K. S. (2019) · Mindfulness · doi:10.1007/s12671-019-01229-0 · Cited by 21
Physical Activity Associated with Prayer Regimes Improves Standing Dynamic Balance of Healthy People
AlAbdulwahab, S. S., Kachanathu, S. J., & Oluseye, K. (2013) · Journal of Physical Therapy Science · doi:10.1589/jpts.25.1565 · Cited by 21
Metadata
- Authors
- Reibel, D. K., Greeson, J. M., Brainard, G. C., & Rosenzweig, S.
- Affiliations
- Thomas Jefferson University (US)
- Corresponding author
- Reibel, Diane K
- Venue
- General Hospital Psychiatry
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 23
- Issue
- 4
- Pages
- 183-192
- ISSN
- 0163-8343 (ISSN-L)
- OpenAlex
- W2141953156
- Cited by
- 431
- References
- 38
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 10 · 2023: 13 · 2022: 6 · 2021: 13 · 2020: 14 · 2019: 25 · 2018: 25 · 2017: 13 · 2016: 18 · 2015: 24 · 2014: 27 · 2013: 28 · 2012: 19
- FWCI
- 12.66
- Type
- journal article
- Language
- en
- Open access
- green
- jdc.jefferson.edu
- Locations
- General Hospital Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- The Medicine Forum (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Keywords
- mindfulness-based stress reduction, mindfulness meditation, health-related quality of life, somatic symptoms, psychological distress, anxiety, depression, symptom maintenance, heterogeneous patient populations, group intervention, well-being
- MeSH terms
- Adult, Aged, Female, Humans, Male, Middle Aged, Patient Compliance, Population Surveillance, Prospective Studies, Psychotherapy, Quality of Life, Stress, Psychological, Health Behavior, Meditation
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