Gap junction wiring: a `new' principle in cell-to-cell communication in the nervous system?1Published on the World Wide Web on 4 November 1997.1

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

Cornell-Bell, A. H., Finkbeiner, S. M., Cooper, M. S., & Smith, S. J. (1990) · Science · doi:10.1126/science.1967852 · Cited by 1,846 · see citing works

Gap junctions: New tools, new answers, new questions

Bennett, M. V. L., Barrio, L. C., Bargiello, T. A., Spray, D. C., Hertzberg, E. L., & Sáez, J. C. (1991) · Neuron · doi:10.1016/0896-6273(91)90241-q · Cited by 970 · see citing works

Transmission at the giant motor synapses of the crayfish

Furshpan, E. J., & Potter, D. (1959) · The Journal of Physiology · doi:10.1113/jphysiol.1959.sp006143 · Cited by 847 · see citing works

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells.

Elfgang, C., Eckert, R., Lichtenberg‐Fraté, H., Butterweck, A., Traub, O., Klein, R. A., Hülser, D. F., & Willecke, K. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.129.3.805 · Cited by 813 · see citing works

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

Sáez, J. C., Connor, J. A., Spray, D. C., & Bennett, M. V. L. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2708 · Cited by 595 · see citing works

Differential expression of three gap junction proteins in developing and mature brain tissues.

Dermietzel, R., Traub, O., Hwang, T. K., Beyer, E. C., Bennett, M. V. L., Spray, D. C., & Willecke, K. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.10148 · Cited by 527 · see citing works

Gap junctions in the brain: where, what type, how many and why?

Dermietzel, R., & Spray, D. C. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90151-b · Cited by 501 · see citing works

Neuronal Domains in Developing Neocortex

Yuste, R., Peinado, A., & Katz, L. C. (1992) · Science · doi:10.1126/science.1496379 · Cited by 490 · see citing works

Calcium Waves in Retinal Glial Cells

Newman, E. A., & Zahs, K. R. (1997) · Science · doi:10.1126/science.275.5301.844 · Cited by 457 · see citing works

Extensive dye coupling between rat neocortical neurons during the period of circuit formation

Peinado, A., Yuste, R., & Katz, L. C. (1993) · Neuron · doi:10.1016/0896-6273(93)90246-n · Cited by 391 · see citing works

Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice.

Nelles, E., Bützler, C., Jung, D., Temme, A., Gabriel, H., Dahl, U., Traub, O., Stümpel, F. T., Jungermann, K. A., Zielasek, J., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9565 · Cited by 387 · see citing works

cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.

Sáez, J. C., Spray, D. C., Nairn, A. C., Hertzberg, E. L., Greengard, P., & Bennett, M. V. L. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.8.2473 · Cited by 369 · see citing works

Dopaminergic modulation of gap junction permeability between amacrine cells in mammalian retina

Hampson, E. C. G. M., Vaney, D., & Weiler, R. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-12-04911.1992 · Cited by 356 · see citing works

Electrotonic Coupling Between Pyramidal Cells: A Direct Demonstration in Rat Hippocampal Slices

MacVicar, B. A., & Dudek, F. E. (1981) · Science · doi:10.1126/science.6266013 · Cited by 329 · see citing works

Calcium waves in astrocytes-filling in the gaps

Finkbeiner, S. M. (1992) · Neuron · doi:10.1016/0896-6273(92)90131-v · Cited by 315 · see citing works

Clusters of Coupled Neuroblasts in Embryonic Neocortex

Turco, J. J. L., & Kriegstein, A. R. (1991) · Science · doi:10.1126/science.1850552 · Cited by 314 · see citing works

Mechanisms and function of intercellular calcium signaling

Sanderson, M. J., Charles, A. C., Boitano, S. A., et al. (1994) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(94)90136-8 · Cited by 308 · see citing works

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

Haefliger, J., Bruzzone, R., Jenkins, N. A., et al. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46052-8 · Cited by 303 · see citing works

A correlation analysis of the regional distribution of central enkephalin and β‐endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Evidence for the existence of two main types of communication in the central nervous system: the volume transmission and the wiring transmission

Agnati, L. F., Fuxé, K., Zoli, M., OZINI, I., Toffano, G., & Ferraguti, F. (1986) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1986.tb07967.x · Cited by 271 · see citing works

Gap junctions, electrotonic coupling, and intercellular communication.

Bennett, M. V. L., & Goodenough, D. A. (1978) · PubMed · Cited by 266 · see citing works

Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells.

Steinberg, T. H., Civitelli, R., Geist, S. T., Robertson, A. J., Hick, E., Veenstra, R. D., Wang, H. Z., Warlow, P. M., Westphale, E. M., & Laing, J. G. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06316.x · Cited by 238 · see citing works

Gap junctions as electrical synapses

Bennett, M. V. L. (1997) · Journal of Neurocytology · doi:10.1023/a:1018560803261 · Cited by 221 · see citing works

Gap junctions in the nervous system.

Rozental, R., Giaume, C., & Spray, D. (2000) · Brain research. Brain research reviews · doi:10.1016/s0165-0173(99)00095-8 · Cited by 219 · see citing works

Cell junction and cyclic AMP: I. Upregulation of junctional membrane permeability and junctional membrane particles by administration of cyclic nucleotide or phosphodiesterase inhibitor

Flagg-Newton, J. L., Dahl, G., & Loewenstein, W. R. (1981) · The Journal of Membrane Biology · doi:10.1007/bf01969452 · Cited by 204 · see citing works

Patterns of neuronal coupling in the retina

Vaney, D. I. (1994) · Progress in Retinal and Eye Research · doi:10.1016/1350-9462(94)90014-0 · Cited by 190 · see citing works

Neuronal coupling and uncoupling in the developing nervous system

Kandler, K. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80093-x · Cited by 187 · see citing works

Role of electrical interactions in synchronization of epileptiform bursts.

Dudek, F. E., Snow, R. W., & Taylor, C. P. (1986) · PubMed · Cited by 180 · see citing works

Multiple connexins confer distinct regulatory and conductance properties of gap junctions in developing heart.

Veenstra, R. D., Wang, H. Z., Westphale, E. M., et al. (1992) · Circulation Research · doi:10.1161/01.res.71.5.1277 · Cited by 176 · see citing works

The Gap Junction Proteins β1-Connexin (Connexin-32) and β2-Connexin (Connexin-26) Can Form Heteromeric Hemichannels

Stauffer, K. A. (1995) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82720-x · Cited by 175 · see citing works

Distribution of mRNAs coding for liver and heart gap junction proteins in the rat central nervous system

Micevych, P. E., & Abelson, L. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903050110 · Cited by 175 · see citing works

Mechanisms of intercellular calcium signaling in glial cells studied with dantrolene and thapsigargin

Charles, A. C., Dirksen, E. R., Merrill, J. E., et al. (1993) · Glia · doi:10.1002/glia.440070203 · Cited by 161 · see citing works

Properties of gap junction channels formed of connexin 45 endogenously expressed in human hepatoma (SKHep1) cells

Moreno, A. P., Laing, J. G., Beyer, E. C., et al. (1995) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1995.268.2.c356 · Cited by 157 · see citing works

Mixed synapses discovered and mapped throughout mammalian spinal cord.

Rash, J. E., Dillman, R. K., Bilhartz, B. L., Duffy, H. S., Whalen, L. R., & Yasumura, T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.9.4235 · Cited by 151 · see citing works

The gap junction family: structure, function and chemistry

Dermietzel, R., Hwang, T. K., & Spray, D. C. (1990) · Anatomy and Embryology · doi:10.1007/bf00186458 · Cited by 146 · see citing works

Activity-dependent short-term enhancement of intercellular coupling

Pereda, A., & Faber, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-03-00983.1996 · Cited by 132 · see citing works

Rapid communication between neurons and astrocytes in primary cortical cultures

Murphy, T. H., Blatter, L. A., Wier, W., & Baraban, J. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-06-02672.1993 · Cited by 125 · see citing works

pH-gated dopaminergic modulation of horizontal cell gap junctions in mammalian retina

Hampson, E. C. G. M., Weiler, R., & Vaney, D. I. (1994) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1994.0010 · Cited by 115 · see citing works

Intercellular communication between ciliated cells in culture

Sanderson, M. J., Chow, I., & Dirksen, E. R. (1988) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1988.254.1.c63 · Cited by 109 · see citing works

Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes.

Willecke, K., Jungbluth, S., Dahl, E., et al. (1990) · PubMed · Cited by 89 · see citing works

Use of alternate promoters for tissue-specific expression of the gene coding for connexin32

Neuhaus, I. M., Dahl, G., & Werner, R. (1995) · Gene · doi:10.1016/0378-1119(94)00899-4 · Cited by 82 · see citing works

Attempts to define functional domains of gap junction proteins with synthetic peptides

Dahl, G., Nonner, W., & Werner, R. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80663-0 · Cited by 81 · see citing works

Intermediate filament change in astrocytes following mild cortical contusion

Baldwin, S. A., & Scheff, S. W. (1996) · Glia · doi:10.1002/(sici)1098-1136(199603)16:3 · Cited by 81 · see citing works

Astrocytes as rapid sensors of peripheral axotomy in the facial nucleus of rats

Rohlmann, A., Laskawi, R., Höfer, A., et al. (1994) · Neuroreport · doi:10.1097/00001756-199401120-00009 · Cited by 78 · see citing works

Regulation of liver metabolism by the hepatic nerves

Jungermann, K. A., Gardemann, A., Beuers, U. H., BALLÉ, C., Sannemann, J., Beckh, K., & Hartmann, H. (1987) · Advances in Enzyme Regulation · doi:10.1016/0065-2571(87)90006-9 · Cited by 77 · see citing works

Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cell

Pereda, A., Nairn, A. C., Wolszon, L., et al. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03704.1994 · Cited by 74 · see citing works

Endothelins Inhibit Junctional Permeability in Cultured Mouse Astrocytes

Giaume, C., Cordier, J., & Glowinski, J. (1992) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1992.tb00198.x · Cited by 74 · see citing works

The coupling pattern of axon-bearing horizontal cells in the mammalian retina

Vaney, D. I. (1993) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1993.0051 · Cited by 70 · see citing works

Expression of connexin43 mRNA in adult rodent brain

Simbürger, E., Stang, A., Kremer, M., & Dermietzel, R. (1997) · Histochemistry and Cell Biology · doi:10.1007/s004180050097 · Cited by 64 · see citing works

Cell junction and cyclic AMP: II. Modulations of junctional membrane permeability, dependent on serum and cell density

Flagg-Newton, J. L., & Loewenstein, W. R. (1981) · The Journal of Membrane Biology · doi:10.1007/bf01969453 · Cited by 60 · see citing works

Molecular Diversity and Plasticity of Gap Junctions in the Nervous System

Dermietzel, R. (1996) · Neuroscience intelligence unit · doi:10.1007/978-3-662-21935-5_2 · Cited by 36 · see citing works

Comparison of pH and calcium dependence of gap junctional conductance.

Dc, S., Harris, A. L., & Mv, B. (1981) · PubMed · Cited by 30 · see citing works

Do Glial Gap Junctions Play a Role in Extracellular Ion Homeostasis?

Ransom, B. R. (1996) · Neuroscience intelligence unit · doi:10.1007/978-3-662-21935-5_9 · Cited by 24 · see citing works

Gap Junctions as Electrical Synapses

Bennett, M. V. L. (1996) · Neuroscience intelligence unit · doi:10.1007/978-3-662-21935-5_4 · Cited by 17 · see citing works

Humoral factors reduce gap junction sensitivity to cytoplasmic pH. I. Organ ablation studies

Moreno, A. P., Spray, D. C., & Ramon, F. (1991) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1991.260.5.c1028 · Cited by 4 · see citing works

Consciousness in the universe

Hameroff, S., & Penrose, R. (2014) · Physics of Life Reviews · doi:10.1016/j.plrev.2013.08.002 · Cited by 983 · see citing works

Electrical synapses between Gaba-Releasing interneurons

Galarreta, M., & Hestrin, S. (2001) · Nature Reviews Neuroscience · doi:10.1038/35077566 · Cited by 434 · see citing works

Glutamate‐mediated neuronal–glial transmission

Verkhratsky, A., & Kirchhoff, F. (2007) · Journal of Anatomy · doi:10.1111/j.1469-7580.2007.00734.x · Cited by 156 · see citing works

The ‘conscious pilot’ — dendritic synchrony moves through the brain to mediate consciousness.

Hameroff, S. (2010) · Journal of Biological Physics · doi:10.1007/s10867-009-9148-x · Cited by 107 · see citing works

Astrocyte–neuron interplay in maladaptive plasticity.

Papa, M., De Luca, C., Petta, F., Alberghina, L., & Cirillo, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.01.010 · Cited by 104 · see citing works

The brain is both neurocomputer and quantum computer

Hameroff, S. R. (2007) · Cognitive Science · doi:10.1080/03640210701704004 · Cited by 103 · see citing works

How quantum brain biology can rescue conscious free will

Hameroff, S. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00093 · Cited by 95 · see citing works

Gap Junctions as Electrical Synapses

Bennett, M. V. L. (1996) · Neuroscience intelligence unit · doi:10.1007/978-3-662-21935-5_4 · Cited by 17 · see citing works

Update on connexins and gap junctions in neurons and glia in the mammalian nervous system

Nagy, J. I., Dudek, F. E., & Rash, J. E. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.05.005 · Cited by 375 · see citing works

Electrical Coupling and Neuronal Synchronization in the Mammalian Brain

Bennett, M. V. L., & Zukin, R. S. (2004) · Neuron · doi:10.1016/s0896-6273(04)00043-1 · Cited by 819 · see citing works