The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Primary insomnia: a risk factor to develop depression?
Abstract
Background Chronic insomnia afflicts approximately 5-10% of the adult population in Western industrialized countries. Insomnia may be secondary, i.e. triggered and/or maintained by psychiatric/organic illnesses, the intake of prescribed/illicit drugs or alcohol, or by a combination of these factors. Insomnia can also occur as primary insomnia, caused by a psychophysiological hyperarousal process. In the present review a literature search was undertaken to identify longitudinal epidemiological studies which investigate the question whether primary insomnia at baseline predicts the development of depression at follow-up measurements.Methods MEDLINE search for the medical subject headings insomnia and depression; identification of longitudinal epidemiological studies with at least two measurement points 1 year apart measuring insomnia and depression and indicating explicit criteria for both disorders.Results Eight relevant epidemiological studies were identified. Almost unambiguously insomnia at baseline significantly predicted an increased depression risk at follow-up 1-3 years later.Conclusion As insomniac symptoms alone seem to be of predictive value for the development of depression in the succeeding years, it would be worthwhile to investigate if early adequate treatment is able to prevent psychiatric sequelae of primary insomnia.
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“Insomnia is not only a symptom of depression, but is a common precursor, with high-quality longitudinal data having established insomnia as an independent risk factor for depression onset.5–7”
From Pilot evaluation of the Sleep Ninja: A smartphone application for adolescent insomnia symptoms (2019) · cites this paper as [7]
In the citing paper
“and especially depression [6]”
From Sleep, hormones, and circadian rhythms throughout the menstrual cycle in healthy women and women with premenstrual dysphoric disorder (2010) · cites this paper as [6]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Impact of sleep debt on metabolic and endocrine function
Spiegel, K., Leproult, R., & Van Cauter, E. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01376-8 · Cited by 3,668
Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.262.11.1479 · Cited by 2,440
Epidemiologic Study of Sleep Disturbances and Psychiatric Disorders: An Opportunity for Prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.1989.03430110069030 · Cited by 2,252
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults
Breslau, N., Roth, T., Rosenthal, L., & Andreski, P. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00188-3 · Cited by 1,831
Psychophysiological insomnia: the behavioural model and a neurocognitive perspective
PERLIS, M. L., GILES, D. E., MENDELSON, W. B., BOOTZIN, R. R., & WYATT, J. K. (1997) · Journal of Sleep Research · doi:10.1046/j.1365-2869.1997.00045.x · Cited by 795
Sleep Loss Results in an Elevation of Cortisol Levels the Next Evening
(1997) · Sleep · doi:10.1093/sleep/20.10.865 · Cited by 745
Insomnia in Young Men and Subsequent Depression: The Johns Hopkins Precursors Study
Chang, P. P., Ford, D. E., Mead, L. A., Cooper, L. A., & Klag, M. J. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009241 · Cited by 674
Sleep and depression--results from psychobiological studies: an overview
Riemann, D., Berger, M., & Voderholzer, U. (2001) · Biological Psychology · doi:10.1016/s0301-0511(01)00090-4 · Cited by 653
Self-citationStress, hypercortisolism and corticosteroid receptors in depression: implicatons for therapy
Holsboer, F. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00352-9 · Cited by 575
Self-reported sleep disturbance as a prodromal symptom in recurrent depression
Perlis, M. L., Giles, D. E., Buysse, D. J., Tu, X. M., & Kupfer, D. J. (1997) · Journal of Affective Disorders · doi:10.1016/s0165-0327(96)01411-5 · Cited by 523
Ernst, C., & Angst, J. (1992) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02190257 · Cited by 450
Paffenbarger, R. S., Lee, I.-M. M., & Leung, R. (1994) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1994.tb05796.x · Cited by 438
The morbidity of insomnia uncomplicated by psychiatric disorders
Weissman, M. M., Greenwald, S., Niño-Murcia, G., & Dement, W. C. (1997) · General Hospital Psychiatry · doi:10.1016/s0163-8343(97)00056-x · Cited by 415
Monjan, Simonsick, & Wallace (1999) · SLEEP · Cited by 402
Chronic insomnia and activity of the stress system
Vgontzas, A. N., Tsigos, C., Bixler, E. O., Stratakis, C. A., Zachman, K., Kales, A., Vela-Bueno, A., & Chrousos, G. P. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(97)00302-4 · Cited by 401
Bonnet, M. H., & Arand, D. L. (1997) · Sleep Medicine Reviews · doi:10.1016/s1087-0792(97)90012-5 · Cited by 363
Prevalence and treatment of insomnia in general practice
Hohagen, F., Rink, K., Käppler, C. D. O., Schramm, E., Riemann, D. W., Weyerer, S. B., & Berger, T. (1993) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02190245 · Cited by 347
Self-citationProdromes and precursors: epidemiologic data for primary prevention of disorders with slow onset
Eaton, W. W., Badawi, M., & Melton, B. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.7.967 · Cited by 337
Does sleep disturbance predict depression in elderly people? A study in inner London.
Livingston, G., Blizard, B., & Mann, A. (1993) · PubMed · Cited by 313
Vollrath, M. E., Wicki, W., & Angst, J. (1989) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf01759584 · Cited by 197
Frank, E., Hlastala, S. A., Ritenour, A., Houck, P. R., Tu, X. M., Monk, T. H., Mallinger, A. G., & Kupfer, D. J. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00241-7 · Cited by 191
Persistent Psychophysiologic (Learned) Insomnia
Hauri, P., & Fisher, J. (1986) · SLEEP · doi:10.1093/sleep/9.1.38 · Cited by 172
Mendelson, W. B., Gillin, J. C., & Wyatt, R. J. (1977) · Springer eBooks · doi:10.1007/978-1-4684-2289-4 · Cited by 149
Sleep loss, a possible factor in augmenting manic episode
Barbini, B., Bertelli, S., Colombo, C., & Smeraldi, E. (1996) · Psychiatry Research · doi:10.1016/s0165-1781(96)02909-5 · Cited by 146
Brabbins, C. J., Dewey, M. E., Copeland, J. R. M., Davidson, I. A., McWilliam, C., Saunders, P., Sharma, V. K., & Sullivan, C. (1993) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.930080604 · Cited by 141
Brown, L. F., Reynolds, C. F., Monk, T. H., Prigerson, H. G., Dew, M. A., Houck, P. R., Mazumdar, S., Buysse, D. J., Hoch, C. C., & Kupfer, D. J. (1996) · Psychiatry Research · doi:10.1016/0165-1781(96)02914-9 · Cited by 96
Sleep-Loss as a Possible Mediator of Diverse Causes of Mania
Wehr, T. A. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.159.4.576 · Cited by 86
Cited by
Sorted by citations
Baglioni, C., Battagliese, G., Feige, B., Spiegelhalder, K., Nissen, C., Voderholzer, U., Lombardo, C., & Riemann, D. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.01.011 · Cited by 2,779
Self-citationSleep function and synaptic homeostasis
Tononi, G., & Cirelli, C. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.05.002 · Cited by 2,151
European guideline for the diagnosis and treatment of insomnia
Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., Espie, C. A., Garcia‐Borreguero, D., Gjerstad, M., Gonçalves, M., et al. (2017) · Journal of Sleep Research · doi:10.1111/jsr.12594 · Cited by 2,049
Self-citationThe hyperarousal model of insomnia: A review of the concept and its evidence
Riemann, D., Spiegelhalder, K., Feige, B., Voderholzer, U., Berger, M., Perlis, M., & Nissen, C. (2010) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2009.04.002 · Cited by 1,789
Self-citationSo depression is an inflammatory disease, but where does the inflammation come from?
Berk, M., Williams, L. J., Jacka, F. N., O’Neil, A., Pasco, J. A., Moylan, S., Allen, N. B., Stuart, A. L., Hayley, A. C., Byrne, M. L., et al. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-200 · Cited by 1,423
Metadata
- Authors
- Riemann, D.
- Affiliations
- University Medical Center Freiburg (DE)
- Corresponding author
- Riemann, D
- ORCID
- Riemann, D
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 76
- Issue
- 1-3
- Pages
- 255-259
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2154516720
- Semantic Scholar
- b8c0f4f8624614a33be6ebf15f3d53fc3d809e0d
- Cited by
- 641
- References
- 28
- Citations by year
- 2026: 19 · 2025: 18 · 2024: 40 · 2023: 27 · 2022: 35 · 2021: 18 · 2020: 25 · 2019: 32 · 2018: 26 · 2017: 32 · 2016: 32 · 2015: 26 · 2014: 32 · 2013: 44 · 2012: 38
- FWCI
- 11.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- FreiDok plus (Universitätsbibliothek Freiburg) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Keywords
- primary insomnia, depression, depression risk prediction, longitudinal epidemiology, insomnia treatment, psychiatric comorbidity
- MeSH terms
- Adult, Aged, Chronic Disease, Depressive Disorder, Female, Humans, Sleep Initiation and Maintenance Disorders, Longitudinal Studies, Male, Middle Aged, Risk Factors, Epidemiologic Studies
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