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Microarrays: biotechnology's discovery platform for functional genomics
Open accessAbstract
Advances in microarray technology enable massive parallel mining of biological data, with biological chips providing hybridization-based expression monitoring, polymorphism detection and genotyping on a genomic scale. Microarrays containing sequences representative of all human genes may soon permit the expression analysis of the entire human genome in a single reaction. These 'genome chips' will provide unprecedented access to key areas of human health, including disease prognosis and diagnosis, drug discovery, toxicology, aging, and mental illness. Microarray technology is rapidly becoming a central platform for functional genomics.
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The New Genomics: Global Views of Biology
Lander, E. S. (1996) · Science · doi:10.1126/science.274.5287.536 · Cited by 1,174
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The microglial sensome revealed by direct RNA sequencing
Hickman, S. E., Kingery, N. D., Ohsumi, T. K., Borowsky, M. L., Wang, L.-C., Means, T. K., & El Khoury, J. (2013) · Nature Neuroscience · doi:10.1038/nn.3554 · Cited by 1,511
Report of the ad hoc committee for the re-evaluation of the species definition in bacteriology.
Stackebrandt, E., Frederiksen, W., Garrity, G. M., Grimont, P. A. D., Kämpfer, P., Maiden, M. C. J., Nesme, X., Rosselló-Mora, R., Swings, J., Trüper, H. G., et al. (2002) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/00207713-52-3-1043 · Cited by 1,540
Blalock, E. M., Geddes, J. W., Chen, K. C., Porter, N. M., Markesbery, W. R., & Landfield, P. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308512100 · Cited by 1,025
Next-generation sequencing technologies and their implications for crop genetics and breeding
Varshney, R. K., Nayak, S. N., May, G. D., & Jackson, S. A. (2009) · Trends in Biotechnology · doi:10.1016/j.tibtech.2009.05.006 · Cited by 936
Metadata
- Authors
- Schena, M., Heller, R. A., Theriault, T. P., Konrad, K., Lachenmeier, E., & Davis, R. W.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 1998-07
- Volume
- 16
- Issue
- 7
- Pages
- 301-306
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2027600997
- Cited by
- 791
- References
- 1
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Schena, M., Heller, R. A., Theriault, T. P., Konrad, K., Lachenmeier, E., & Davis, R. W. (1998). Microarrays: biotechnology's discovery platform for functional genomics. Trends in Biotechnology. https://doi.org/10.1016/s0167-7799(98)01219-0
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