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Cited by 294

The DOI matches its Crossref record; 152 of the 152 references it cites were found in a registry or an index.

Themes and variations in prokaryotic cell division

Open access
Margolin, W·2000·FEMS Microbiology Reviews

Abstract

Perhaps the biggest single task facing a bacterial cell is to divide into daughter cells that contain the normal complement of chromosomes. Recent technical and conceptual breakthroughs in bacterial cell biology, combined with the flood of genome sequence information and the excellent genetic tools in several model systems, have shed new light on the mechanism of prokaryotic cell division. There is good evidence that in most species, a molecular machine, organized by the tubulin-like FtsZ protein, assembles at the site of division and orchestrates the splitting of the cell. The determinants that target the machine to the right place at the right time are beginning to be understood in the model systems, but it is still a mystery how the machine actually generates the constrictive force necessary for cytokinesis. Moreover, although some cell division determinants such as FtsZ are present in a broad spectrum of prokaryotic species, the lack of FtsZ in some species and different profiles of cell division proteins in different families suggests that there are diverse mechanisms for regulating cell division.

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Metadata

Authors
Margolin, W.
Venue
FEMS Microbiology Reviews
Publisher
Wiley
Published
2000-10
Volume
24
Issue
4
Pages
531-548
ISSN
0168-6445 (ISSN-L)
OpenAlex
W2083026006
Cited by
294
References
152
FWCI
15.40
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Themes and variations in prokaryotic cell division. https://app.cochat.ai/papers/10.1016/s0168-6445(00)00038-3
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Margolin, W. (2000). Themes and variations in prokaryotic cell division. FEMS Microbiology Reviews. https://doi.org/10.1016/s0168-6445(00)00038-3

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