Cited by 122Mitochondrial Function and PathologyGenomics and Phylogenetic StudiesChromosomal and Genetic Variations

Linear mitochondrial genomes: 30 years down the line

Open access
Nosek, Jozef, Tomáška, L'Ubomı́r, Fukuhara, Hiroshi, Suyama, Yoshitaka, Kováč, Ladislav·1998·Trends in Genetics

Abstract

At variance with the earlier belief that mitochondrial genomes are represented by circular DNA molecules, a large number of organisms have been found to carry linear mitochondrial DNA. Studies of linear mitochondrial genomes might provide a novel view on the evolutionary history of organelle genomes and contribute to delineating mechanisms of maintenance and functioning of telomeres. Because linear mitochondrial DNA is present in a number of human pathogens, its replication mechanisms might become a target for drugs that would not interfere with replication of human circular mitochondrial DNA.

Integrity signals

Registry

Crossref · 10.1016/s0168-9525(98)01443-7

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Nosek, J., Tomáška, L., Fukuhara, H., Suyama, Y., & Kováč, L.
Affiliations
  • Comenius University Bratislava (SK)
  • Institut Curie (FR)
  • University of Pennsylvania (US)
Venue
Trends in Genetics
Publisher
Elsevier BV
Published
1998-05
Volume
14
Issue
5
Pages
184-188
ISSN
0168-9525 (ISSN-L)
OpenAlex
W1980779505
Cited by
122
References
39
Citations by year
2026: 1 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 9 · 2019: 5 · 2018: 1 · 2017: 2 · 2016: 4 · 2015: 4 · 2014: 1 · 2013: 6 · 2012: 4
FWCI
0.48
Type
journal article
Language
en
Open access
Locations
  • Trends in Genetics (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
  • Howard Hughes Medical Institute
  • Vedecká Grantová Agentúra MŠVVaŠ SR a SAV
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
Keywords
mitochondrial genome evolution, telomeres, telomere maintenance, mitochondrial DNA replication, human pathogens, antiviral drug targets, organelle genomes
MeSH terms
Animals, DNA Replication, DNA, Mitochondrial, Biological Evolution, Humans, Telomere

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review