Role of meiosis activating sterols, MAS, in induced oocyte maturation
Abstract
Meiosis of follicle enclosed oocytes is maintained in the prophase of the first meiotic division and oocytes do not spontaneously resume meiosis during oocyte growth and follicle development. Arrest of the meiotic process is most likely secured by the presence of follicular purines, e.g. hypoxanthine, which maintain high levels of cAMP in the oocyte and which also in vitro prevent oocytes from resuming meiosis. Only in response to the mid-cycle surge of gonadotropins will oocytes of preovulatory follicles overcome the meiosis arresting effect of hypoxanthine and resume meiosis proceeding to the metaphase of the second meiotic division. Morphologically, resumption of meiosis is observed by the disappearance of the oocyte's nuclear membrane (germinal vesicle), a process called germinal vesicle breakdown (GVB). The molecular mechanism down-stream to receptor activation by which the mid-cycle surge of gonadotropins induces oocytes to resume meiosis is, however, only partly understood. The oocyte itself lacks gonadotropin receptors and its action is mediated through the attached cumulus cells. In vitro it has been shown that FSH induces synthesis of a signal in the cumulus cells, which overcomes the meiosis arresting effect of hypoxanthine. We have shown that a group of sterols, meiosis activating sterols (MAS), induces oocyte maturation in vitro even in oocytes depleted of cumulus cells. MAS were identified as intermediates in the cholesterol biosynthesis between lanosterol and c…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Most of the 8,9-unsaturated sterols shown here to enhance oligodendrocyte formation have previously been shown to function as signaling lipids in oocytes by inducing the resumption of meiosis.
“Most of the 8,9-unsaturated sterols shown here to enhance oligodendrocyte formation have previously been shown to function as signaling lipids in oocytes by inducing the resumption of meiosis19,20”
From Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination (2018) · cites this paper as [19]
Past work suggested nuclear hormone receptors (NHRs) may play a role in the direct cellular targets of 8,9-unsaturated 'meiosis-activating sterols'.
“While the direct cellular targets of 8,9-unsaturated ‘meiosis-activating sterols’ remain poorly understood, past work suggested nuclear hormone receptors (NHRs) may play a role19”
From Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination (2018) · cites this paper as [19]
Cites
An oxysterol signalling pathway mediated by the nuclear receptor LXRα
Janowski, B. A., Willy, P. J., Devi, T. R., Falck, J. R., & Mangelsdorf, D. J. (1996) · Nature · doi:10.1038/383728a0 · Cited by 1,754 · see citing works
Oxysterols: Modulators of Cholesterol Metabolism and Other Processes
Schroepfer, G. J. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.1.361 · Cited by 965 · see citing works
Schultz, R. M., Montgomery, R. R., & Belanoff, J. R. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90085-4 · Cited by 419 · see citing works
Chemical structure of sterols that activate oocyte meiosis
Byskov, A. G., Andersen, C. Y., Nordholm, L., Thøgersen, H., Guoliang, X., Wassmann, O., Andersen, J. V., Guddal, E., & Roed, T. (1995) · Nature · doi:10.1038/374559a0 · Cited by 354 · see citing works
Self-citationDowns, S. M., Daniel, S. A. J., & Eppig, J. J. (1988) · Journal of Experimental Zoology · doi:10.1002/jez.1402450113 · Cited by 347 · see citing works
Eppig, J. J. (1982) · Developmental Biology · doi:10.1016/0012-1606(82)90314-1 · Cited by 286 · see citing works
Identification of maturation-inducing steroid in a teleost, the amago salmon (Oncorhynchus rhodurus)
Nagahama, Y., & Adachi, S. (1985) · Developmental Biology · doi:10.1016/0012-1606(85)90469-5 · Cited by 266 · see citing works
Rat oocyte maturation in vitro : Relief of cyclic AMP inhibition by gonadotropins
Dekel, N., & Beers, W. H. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.9.4369 · Cited by 252 · see citing works
Yoshida, Y., & Aoyama, Y. (1987) · Biochemical Pharmacology · doi:10.1016/0006-2952(87)90694-0 · Cited by 247 · see citing works
Amsterdam, A., Koch, Y., Lieberman, M. E., & Lindner, H. R. (1975) · The Journal of Cell Biology · doi:10.1083/jcb.67.3.894 · Cited by 221 · see citing works
Byskov, A. G., Andersen, C. Y., Hossaini, A., & Guoliang, X. (1997) · Molecular Reproduction and Development · doi:10.1002/(sici)1098-2795(199703)46:3 · Cited by 173 · see citing works
Self-citationMouse oocytes regulate granulosa cell steroidogenesis.
Vanderhyden, B. C., Cohen, J. N., & Morley, P. (1993) · Endocrinology · doi:10.1210/endo.133.1.8319589 · Cited by 166 · see citing works
Strömstedt, M., Rozman, D., & Waterman, M. R. (1996) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1996.0193 · Cited by 163 · see citing works
Schroepfer, G. J. (1982) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.51.070182.003011 · Cited by 143 · see citing works
Differential modulation of rat follicle cell gap junction populations at ovulation
Larsen, W. J., Wert, S. E., & Brunner, G. D. (1987) · Developmental Biology · doi:10.1016/0012-1606(87)90332-0 · Cited by 139 · see citing works
Mouse Oocytes Regulate Granulosa Cell Steroidogenesis Throughout Follicular Development
Vanderhyden, B. C., & Macdonald, E. A. (1998) · Biology of Reproduction · doi:10.1095/biolreprod59.6.1296 · Cited by 123 · see citing works
Oxberry, B. A., & Greenwald, G. S. (1982) · Biology of Reproduction · doi:10.1095/biolreprod27.2.505 · Cited by 105 · see citing works
Grøndahl, C. (1998) · Biology of Reproduction · doi:10.1095/biolreprod58.5.1297 · Cited by 100 · see citing works
Fagbohun, C. F., & Downs, S. M. (1991) · Biology of Reproduction · doi:10.1095/biolreprod45.6.851 · Cited by 92 · see citing works
Progesterone Inhibits Cholesterol Biosynthesis in Cultured Cells
Metherall, J. E., Waugh, K., & Li, H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.5.2627 · Cited by 91 · see citing works
Schorderet‐Slatkine, S., Schorderet, M., Boquet, P., Godeau, F., & Baulieu, É.-É. (1978) · Cell · doi:10.1016/0092-8674(78)90052-1 · Cited by 86 · see citing works
Sadler, K. C., & RUDERMAN, J. V. (1998) · Developmental Biology · doi:10.1006/dbio.1998.8869 · Cited by 84 · see citing works
Kondo, T., Yanagawa, T., Yoshida, N., & Yamashita, M. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8673 · Cited by 83 · see citing works
Inhibitors of sterol biosynthesis and their applications
MERCER, E. I. (1993) · Progress in Lipid Research · doi:10.1016/0163-7827(93)90016-p · Cited by 78 · see citing works
Guoliang, X., Byskov, A. G., & Andersen, C. Y. (1994) · Molecular Reproduction and Development · doi:10.1002/mrd.1080390104 · Cited by 77 · see citing works
Self-citationHegele‐Hartung, C., Kuhnke, J., Lessl, M., Grøndahl, C., Ottesen, J. L., Beier, H. M., Eisner, S., & Eichenlaub-Ritter, U. (1999) · Biology of Reproduction · doi:10.1095/biolreprod61.5.1362 · Cited by 72 · see citing works
Oocyte donation: the legislative framework in Western Europe
Gunning, J. (1998) · Human Reproduction · doi:10.1093/humrep/13.suppl_2.98 · Cited by 62 · see citing works
Genetic Defects in Postsqualene Cholesterol Biosynthesis
Moebius, F. F., Fitzky, B. U., & Glossmann, H. H. (2000) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(00)00235-6 · Cited by 60 · see citing works
Mouse oocytes suppress cAMP-induced expression of LH receptor mRNA by granulosa cells in vitro
Eppig, J. J., Pendola, F. L., & Wigglesworth, K. (1998) · Molecular Reproduction and Development · doi:10.1002/(sici)1098-2795(199803)49:3 · Cited by 60 · see citing works
Vaknin, K. M., Lazar, S., Popliker, M., & TSAFRIRI, A. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.1.299 · Cited by 59 · see citing works
Meiosis-Activating Sterol and the Maturation of Isolated Mouse Oocytes1
Downs, S. M., Ruan, B. H., & Schroepfer, G. J. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.1.80 · Cited by 56 · see citing works
Progestins block cholesterol synthesis to produce meiosis‐activating sterols
Lindenthal, B., Holleran, A. L., Aldaghlas, T., Ruan, B. H., Schroepfer, G. J., Wilson, W. K., & Kelleher, J. K. (2001) · The FASEB Journal · doi:10.1096/fj.00-0214com · Cited by 50 · see citing works
TSAFRIRI, A. (1998) · Molecular Human Reproduction · doi:10.1093/molehr/4.5.483 · Cited by 47 · see citing works
Grøndahl, C., Lessl, M., Faerge, I., Hegele‐Hartung, C., Wassermann, K., & Ottesen, J. L. (2000) · Biology of Reproduction · doi:10.1095/biolreprod62.3.775 · Cited by 47 · see citing works
Leonardsen, L., Stromstedt, M., Jacobsen, D., Kristensen, K., Baltsen, M., Andersen, C. Y., & Byskov, A. G. (2000) · Reproduction · doi:10.1530/jrf.0.1180171 · Cited by 47 · see citing works
Self-citationCavilla, J. L., Kennedy, C. R., Baltsen, M., Klentzeris, L. D., Byskov, A. G., & Hartshorne, G. M. (2001) · Human Reproduction · doi:10.1093/humrep/16.3.547 · Cited by 46 · see citing works
Self-citationYoshida, Y., Yamashita, C., Noshiro, M., Fukuda, M., & Aoyama, Y. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0929 · Cited by 44 · see citing works
Human oocyte maturation in vitro is stimulated by meiosis-activating sterol
Grøndahl, C., Hansen, T. H., Marky-Nielsen, K., Ottesen, J. L., & Hyttel, P. (2000) · Human Reproduction · doi:10.1093/humrep/15.suppl_5.3 · Cited by 43 · see citing works
Ruan, B. H., Watanabe, S., Eppig, J. J., Kwoh, C., Dzidic, N., Pang, J., Wilson, W. K., & Schroepfer, G. J. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32499-8 · Cited by 38 · see citing works
6 Gonadotropin-lnduced Resumption of Oocyte Meiosis and Meiosis-Activating Sterols
Andersen, C. Y., Baltsen, M., & Byskov, A. G. (1998) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60273-2 · Cited by 37 · see citing works
Self-citationKyozuka, K., Deguchi, R., Yoshida, N., & Yamashita, M. (1997) · Developmental Biology · doi:10.1006/dbio.1996.8470 · Cited by 36 · see citing works
Ruan, B. H., Gerst, N., Emmons, G. T., Shey, J., & Schroepfer, G. J. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30045-6 · Cited by 34 · see citing works
Lu, Z., Xia, G., Byskov, A. G., & Andersen, C. Y. (2000) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00223-9 · Cited by 30 · see citing works
Self-citationBaltsen, M., & Byskov, A. G. (1999) · Biomedical Chromatography · doi:10.1002/(sici)1099-0801(199910)13:6 · Cited by 29 · see citing works
Self-citationDekel, N., Galiani, D., & Beers, W. H. (1988) · Biology of Reproduction · doi:10.1095/biolreprod38.3.517 · Cited by 29 · see citing works
Ayub, M., & LEVELL, M. J. (1990) · Biochemical Pharmacology · doi:10.1016/0006-2952(90)90456-u · Cited by 25 · see citing works
Brück, I., BÉZARD, J., Baltsen, M., Synnestvedt, B., Couty, I., Greve, T., & Duchamp, G. (2000) · Reproduction · doi:10.1530/jrf.0.1180351 · Cited by 22 · see citing works
Faerge, I., Grøndahl, C., Ottesen, J. L., & Hyttel, P. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.2.527 · Cited by 21 · see citing works
Elusive locus of control in biological development: Genetic versus developmental programs
Keller, E. F. (1999) · Journal of Experimental Zoology · doi:10.1002/(sici)1097-010x(19991015)285:3 · Cited by 14 · see citing works
Abdelmajid, H., Rivailler, P., Krantic, S. M., & Guerrier, P. (1994) · Experimental Cell Research · doi:10.1006/excr.1994.1163 · Cited by 12 · see citing works
Ruan, B. H., Wilson, W. K., & Schroepfer, G. J. (1998) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(98)00016-x · Cited by 11 · see citing works
Testicular concentration of meiosis-activating sterol is associated with normal testicular descent
Bøgh, I. B., Baltsen, M., Byskov, A. G., & Greve, T. (2001) · Theriogenology · doi:10.1016/s0093-691x(01)00459-9 · Cited by 10 · see citing works
Self-citationAndersen, C. Y., & Byskov, A. G. (2002) · Steroids · doi:10.1016/s0039-128x(02)00041-7 · Cited by 8 · see citing works
Self-citationSynthesis of Meiosis-Activating Sterols Containing Fluorine.
Wenckens, M., Grønvald, F. C., Hansen, J. B., Matsson, O., Trocha-Grimshaw, J., Hammerich, O., Søtofte, I., & Långström, B. (1998) · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · doi:10.3891/acta.chem.scand.52-0503 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 55 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Zarn, J. A., Brüschweiler, B. J., & Schlatter, J. R. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5785 · Cited by 486 · see citing works
Mehlmann, L. M. (2005) · Reproduction · doi:10.1530/rep.1.00793 · Cited by 484 · see citing works
Qiao, J., & Feng, H. L. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq032 · Cited by 479 · see citing works
Hurk, R. V. D., & Zhao, J. (2004) · Theriogenology · doi:10.1016/j.theriogenology.2004.08.005 · Cited by 418 · see citing works
Sutton‐McDowall, M. L. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg009 · Cited by 409 · see citing works
Meiosis in oocytes: predisposition to aneuploidy and its increased incidence with age
Jones, K. T. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmm043 · Cited by 228 · see citing works
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Hubler, Z., Allimuthu, D., Bederman, I., Elitt, M. S., Madhavan, M., Allan, K. C., Shick, H. E., Garrison, E., T. Karl, M., Factor, D. C., et al. (2018) · Nature · doi:10.1038/s41586-018-0360-3 · Cited by 226 · see citing works
Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes
Herman, G. E. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg072 · Cited by 189 · see citing works
Proteomic analysis of human follicular fluid from fertile women
Zamah, A. M., Hassis, M. E., Albertolle, M. E., & Williams, K. E. (2015) · Clinical Proteomics · doi:10.1186/s12014-015-9077-6 · Cited by 132 · see citing works
The signal pathway of gonadotrophins-induced mammalian oocyte meiotic resumption
Zhang, M., Ouyang, H. W., & Xia, G. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap031 · Cited by 130 · see citing works
The Regulation of Oocyte Maturation
Voronina, E., & Wessel, G. M. (2003) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)58003-6 · Cited by 127 · see citing works
Chen, L., Ma, M.-Y., Sun, M., Jiang, L.-Y., Zhao, X.-T., Fang, X.-X., Lam, S. M., Shui, G., Luo, J., Shi, X.-J., et al. (2019) · Journal of Lipid Research · doi:10.1194/jlr.ra119000201 · Cited by 108 · see citing works
Trösken, E. R., Adamska, M., Arand, M., Zarn, J. A., Patten, C., Völkel, W., & Lutz, W. K. (2006) · Toxicology · doi:10.1016/j.tox.2006.08.007 · Cited by 95 · see citing works
Lipid Metabolic Process Involved in Oocyte Maturation During Folliculogenesis
Liu, T., Qu, J., Tian, M., Yang, R. J., Song, X., Li, R., Yan, J., & Qiao, J. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.806890 · Cited by 83 · see citing works
Borman, S. M., Chaffin, C. L., Schwinof, K. M., Stouffer, R. L., & Zelinski, M. B. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.023390 · Cited by 69 · see citing works
Chen, X., Zheng, J., Zhang, J., Duan, M., Xu, H., Zhao, W., Yang, Y., Wang, C., & Xu, Y. B. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155610 · Cited by 67 · see citing works
Donnay, I., Faerge, I., Grøndahl, C., Verhaeghe, B., Sayoud, H., Ponderato, N., Galli, C., & Lazzari, G. (2004) · Theriogenology · doi:10.1016/j.theriogenology.2003.12.019 · Cited by 66 · see citing works
Human immature oocytes grow during culture for IVM
Cavilla, J. L., Kennedy, C. R., Byskov, A. G., & Hartshorne, G. M. (2007) · Human Reproduction · doi:10.1093/humrep/dem178 · Cited by 65 · see citing works
Self-citationGrupen, C. G., & Armstrong, D. T. (2010) · Reproduction Fertility and Development · doi:10.1071/rd09307 · Cited by 60 · see citing works
Sutton‐McDowall, M. L., Gilchrist, R. B., & Thompson, J. G. (2005) · Reproduction Fertility and Development · doi:10.1071/rd04135 · Cited by 59 · see citing works
Bivens, C. L. M., Grøndahl, C., Murray, A., Blume, T., Su, Y., & Eppig, J. J. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.026351 · Cited by 58 · see citing works
Uhm, S. J., Gupta, M. K., Yang, J. H., Chung, H., Min, T. S., & Lee, H. T. (2010) · Theriogenology · doi:10.1016/j.theriogenology.2009.11.029 · Cited by 56 · see citing works
Studies of the role of steroid hormone in the regulation of oocyte maturation in cattle
Wang, H. F., Isobe, N., Kumamoto, K., Yamashiro, H., Yamashita, Y., & Terada, T. (2006) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-4-4 · Cited by 55 · see citing works
Developmental competence of in vivo and in vitro matured oocytes: A review
R, B. M., Demyda-Peyrás, S., Millán, M. M., & Género, E. R. (2011) · Biotechnology and Molecular Biology Reviews · doi:10.5897/bmbr2011.0015 · Cited by 51 · see citing works
Disorders of sterol synthesis: Beyond Smith–Lemli–Opitz syndrome
Herman, G. E., & Kratz, L. E. (2012) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.31340 · Cited by 50 · see citing works
O’Brien, M., Chantha, S.-C., Rahier, A., & Matton, D. P. (2005) · PLANT PHYSIOLOGY · doi:10.1104/pp.105.066639 · Cited by 48 · see citing works
Metabolism and Biological Activities of 4-Methyl-Sterols
Darnet, S. H., & Schaller, H. (2019) · Molecules · doi:10.3390/molecules24030451 · Cited by 43 · see citing works
Bivens, C. L. M., Lindenthal, B., O’Brien, M. J., Wigglesworth, K., Blume, T., Grøndahl, C., & Eppig, J. J. (2004) · Human Reproduction · doi:10.1093/humrep/deh436 · Cited by 41 · see citing works
Cukurcam, S., Betzendahl, I., Michel, G., Vogt, E.-J., Hegele‐Hartung, C., Lindenthal, B., & Eichenlaub-Ritter, U. (2006) · Human Reproduction · doi:10.1093/humrep/del442 · Cited by 39 · see citing works
Conservation and cloning of CYP51: a sterol 14α-demethylase from Mycobacterium smegmatis
Jackson, C. J., Lamb, D. C., Marczylo, T. H., Parker, J. E., Manning, N. J., Kelly, D. E., & Kelly, S. L. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)03078-4 · Cited by 39 · see citing works
Cunningham, D., DeBarber, A. E., Bir, N., Binkley, L., Merkens, L. S., Steiner, R. D., & Herman, G. E. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv042 · Cited by 38 · see citing works
Organelle transport during mouse oocyte differentiation in germline cysts
Ikami, K., Nuzhat, N., & Lei, L. (2016) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2016.12.002 · Cited by 37 · see citing works
Emerging roles for LXRs and LRH-1 in female reproduction
Mouzat, K., Baron, S., Marceau, G., Caira, F., Sapin, V., Volle, D. H., Lumbroso, S., & Lobaccaro, J. A. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.06.009 · Cited by 35 · see citing works
Kane, M. T. (2003) · Animal Reproduction Science · doi:10.1016/s0378-4320(03)00164-7 · Cited by 35 · see citing works
Are steroids dispensable for meiotic resumption in mammals?
TSAFRIRI, A., & Motola, S. (2007) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2007.08.005 · Cited by 34 · see citing works
Morrison, A. M. S., Goldstone, J. V., Lamb, D. C., Kubota, A., Lemaire, B., & Stegeman, J. J. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.12.009 · Cited by 33 · see citing works
Electron Transfer Pathways in Cholesterol Synthesis
Porter, T. D. (2015) · Lipids · doi:10.1007/s11745-015-4065-1 · Cited by 32 · see citing works
Jin, S., Zhang, M., Lei, L., Wang, C., Fu, M., Ning, G., & Xia, G. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.01.008 · Cited by 30 · see citing works
Gonadotropin-controlled mammal oocyte meiotic resumption
Zhang, M. (2006) · Frontiers in bioscience · doi:10.2741/2064 · Cited by 28 · see citing works
Meiosis-activating sterol protects oocytes from precocious chromosome segregation
Cukurcam, S. (2003) · Human Reproduction · doi:10.1093/humrep/deg378 · Cited by 28 · see citing works
Abnormalities of Oocyte Maturation: Mechanisms and Implications
Baldini, G. M., Lot, D., Malvası, A., Laganà, A. S., Vimercati, A., Dellino, M., Cicinelli, E., Baldini, D., & Trojano, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212197 · Cited by 25 · see citing works
Gómez‐Coronado, D., Lasunción, M. A., Martı́nez-Botas, J., & Fernández‐Suárez, M. E. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.08.015 · Cited by 24 · see citing works
Wang, C., Xu, B., Zhou, B., Zhang, C., Yang, J., Ouyang, H. W., Ning, G., Zhang, M., Shen, J., & Xia, G. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m800533-jlr200 · Cited by 21 · see citing works
Nascimento, A., Albornoz, M., Che, L., Visintin, J. A., & Bordignon, V. (2009) · Reproduction in Domestic Animals · doi:10.1111/j.1439-0531.2009.01368.x · Cited by 21 · see citing works
Unearthing the Janus-face cholesterogenesis pathways in cancer
Madan, B., Virshup, D. M., Nes, W. D., & Leaver, D. J. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114611 · Cited by 18 · see citing works
Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome
Bokal, E. V., Tacer, K. F., Vrbnjak, M., Lepoša, S., Virant‐Klun, I., Verdenik, I., & Rozman, D. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.01.013 · Cited by 18 · see citing works
Bergh, C. (2004) · Human Reproduction · doi:10.1093/humrep/deh388 · Cited by 18 · see citing works
The spectrum of in vitro maturation in clinical practice: the current insight
Ahmad, M. F., Elias, M. H., Jin, N. M., Abu, M. A., Syafruddin, S. E., Zainuddin, A. A., Suzuki, N., & Karim, A. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1192180 · Cited by 17 · see citing works
Frisso, G., Gelzo, M., Procopio, E., Sica, C., Lenza, M. P., Russo, A. D., Donati, M. A., Salvatore, F., & Corso, G. (2017) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2017.06.013 · Cited by 16 · see citing works
Molecular aspects of follicular development
Huang, Z., & Wells, D. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511921896.013 · Cited by 15 · see citing works
Methyl Paraben Affects Porcine Oocyte Maturation Through Mitochondrial Dysfunction
Huang, H., Huang, C., Li, Y., Liang, X., Kim, N., & Xu, Y. (2024) · Biomolecules · doi:10.3390/biom14111466 · Cited by 15 · see citing works
Guo, R., Wang, X., Li, Q., Sun, X., Zhang, J., & Hao, R. (2019) · Theriogenology · doi:10.1016/j.theriogenology.2019.11.012 · Cited by 15 · see citing works
Liver X Receptors and female reproduction: when cholesterol meets fertility!
Lobaccaro, J. A., Gallot, D., Lumbroso, S., & Mouzat, K. (2013) · PubMed · doi:10.3275/8765 · Cited by 15 · see citing works
Stricker, S. A., Cline, C., & Goodrich, D. (2013) · Biological Bulletin · doi:10.1086/bblv224n3p137 · Cited by 13 · see citing works
Effects of lanosterol on in vitro maturation of porcine oocytes
Marco‐Jiménez, F., Llobat, L., & Vicente, J. S. (2009) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2009.04.008 · Cited by 13 · see citing works
Loft, A. G., Bergh, C., Ziebe, S., Lundin, K., Andersen, A. N., Wikland, M., Kim, H., & Arce, J. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.06.014 · Cited by 12 · see citing works
Ergosterol Is Critical for Sporogenesis in Cryptococcus neoformans
Matha, A. R., Xie, X., & Lin, X. (2024) · Journal of Fungi · doi:10.3390/jof10020106 · Cited by 11 · see citing works
Dietary phytosterols induce infertility in female mice via epigenomic modulations
Yamanashi, Y., Komine, T., Hirota, Y., Suzuki, H., Osuga, Y., & Takada, T. (2024) · Communications Biology · doi:10.1038/s42003-024-07233-y · Cited by 10 · see citing works
Park, S.-H., & Yu, I. (2012) · Zygote · doi:10.1017/s0967199412000585 · Cited by 10 · see citing works
Insights into female germ cell biology: from in vivo development to in vitro derivations
Kee, K., & Jung, D. (2014) · Asian Journal of Andrology · doi:10.4103/1008-682x.148077 · Cited by 9 · see citing works
Song, X., Tai, P., Yan, J., Xu, B., Chen, X., Ouyang, H. W., Zhang, M., & Xia, G. (2008) · Reproduction Fertility and Development · doi:10.1071/rd08085 · Cited by 8 · see citing works
Loft, A., Ziebe, S., Erb, K., Rasmussen, P. E., Agerholm, I., Hauge, B., Bungum, M., Bungum, L. J., Grøndahl, C., & Lyby, K. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.05.017 · Cited by 8 · see citing works
Hao, R., Zhang, C., Lv, L., Shi, L., & Yue, W. (2013) · Theriogenology · doi:10.1016/j.theriogenology.2013.05.005 · Cited by 7 · see citing works
Differences in Sterol Composition between Male and Female Gonads of Dominant Limpet Species
Kawashima, H., Ohnishi, M., & Ogawa, S. (2009) · Lipids · doi:10.1007/s11745-009-3308-4 · Cited by 7 · see citing works
Byskov, A. G., & Westergaard, L. G. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3479-7.10184-3 · Cited by 6 · see citing works
Self-citationde Souza, R. M. (2005) · doi:10.11606/d.10.2005.tde-19102006-115359 · Cited by 6 · see citing works
Kawashima, H., Ohnishi, M., & Ogawa, S. (2013) · Journal of Oleo Science · doi:10.5650/jos.62.465 · Cited by 5 · see citing works
Marco‐Jiménez, F., Vicente, J. S., & Viudes-de-Castro, M. P. (2011) · Zygote · doi:10.1017/s096719941100044x · Cited by 4 · see citing works
Byskov, A. G., & Westergaard, L. G. (2004) · Elsevier eBooks · doi:10.1016/b978-0-7216-9654-6.50193-4 · Cited by 4 · see citing works
Self-citationThe rational development of improved in vitro maturation of bovine oocytes
McDowall, M. (2004) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · Cited by 3 · see citing works
Song, X., Ouyang, H. W., Tai, P., Chen, X., Xu, B., Yan, J., Xia, G., & Zhang, M. (2009) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.2009.80150 · Cited by 2 · see citing works
Zırh, S., Zırh, E. B., Erol, S., Sokmensuer, L. K., Bozdağ, G., & Muftuoglu, S. F. (2024) · Scientific Reports · doi:10.1038/s41598-024-76281-5 · Cited by 2 · see citing works
Expression of Interleukin–6 and Interleukin-6 Receptor in Ovine Oocytes During In vitroMaturation
Zhao, X., Cang, M., Xiao-yu, G. A. O., Yang, M., Yuan, J., Zhu, B., Wang, Z., & Liu, D. (2012) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(12)60131-2 · Cited by 2 · see citing works
Dang, K. N., Hashan, M. R., Minh, L. H. N., Khalaf, K. M., Ibrahim, H. Y., Dessì, A., Azzam, M. A., Loc, T. T. H., Hirayama, K., & Huy, N. T. (2020) · Fertility & Reproduction · doi:10.1142/s2661318220500176 · Cited by 2 · see citing works
Sharma, K., Ammar, O. F., Fraire-Zamora, J. J., Uraji, J., Thomson, A., Aydin, B., Ezzati, M., Alteri, A., & Liperis, G. (2024) · Human Reproduction · doi:10.1093/humrep/deae080 · Cited by 1 · see citing works
Factors affecting the developmental competence of pig oocytes matured in vitro.
Bagg, M. A. (2007) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · Cited by 1 · see citing works
Schatten, G. P. (2002) · Nature Medicine · doi:10.1038/nm-fertilitys19 · Cited by 1 · see citing works
Role of Protein Phosphatase-2A (PP-2A) in the Control of Mitosis and Meiosis.Preprint
Tung, H. Y. L. (2020) · doi:10.14293/s2199-1006.1.sor-.pp2sopb.v1 · Cited by 1 · see citing works
Maternal Age and Oocyte Competence
Eichenlaub-Ritter, U., & Sun, F. (2004) · Springer eBooks · doi:10.1007/978-1-4419-8955-0_8
LA COMPETENCIA DEL OVOCITO: QUÉ, CÓMO Y CUÁNDO The Oocite Competence: What, How and When
Tarazona, A. M., López, A., & Olivera-Angel, M. (2010) · Acta Biológica Colombiana
Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells
Rung, E. (2006) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Regulación de la maduración de ovocitos por factores paracrinos
Lattanzi, M. L. (2010) · Repositorio Digital Institucional de la Universidad de Buenos Aires (Universidad de Buenos Aires)
Reproductive biology and cryobiology
Donnez, J., & Kim, S. S. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511921896.012
Gasperin, B. G. (2009) · Americanae (AECID Library)
Chemical Biology of Sterols, Triterpenoids and Other Natural Products
Zhou, W., & Guo, D. (2019) · MDPI eBooks · doi:10.3390/books978-3-03897-417-8
Lyons, D. A., & Almeida, R. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733692644.793550120
Poitrinal, A., Dupont, L., Dollet, S., Kerksiek, A., Chaput, L., Pereira, B., Lucas, C., Riche, L., Chansel‐Debordeaux, L., Prades, M., et al. (2026) · Cancers · doi:10.3390/cancers18091451
- Authors
- Byskov, A. G., Andersen, C. Y., & Leonardsen, L.
- Affiliations
- University of Copenhagen (DK)
- Corresponding author
- Byskov, Anne Grete
- Venue
- Molecular and Cellular Endocrinology
- Publisher
- Elsevier BV
- Published
- 2002-02
- Volume
- 187
- Issue
- 1-2
- Pages
- 189-196
- ISSN
- 0303-7207 (ISSN-L)
- OpenAlex
- W2089838946
- Cited by
- 88
- References
- 55
- Citations by year
- 2026: 1 · 2024: 6 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 1 · 2013: 5 · 2012: 5
- FWCI
- 7.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular and Cellular Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
- Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Reproductive Physiology in Livestock
- Keywords
- meiosis-activating sterols, oocyte maturation, meiotic resumption, germinal vesicle breakdown, follicular fluid, cholesterol biosynthesis, lanosterol, FSH signaling, signal transduction, cumulus cells, hypoxanthine, gonadotropin surge, sterol synthesis inhibitors
- MeSH terms
- Animals, Cell Differentiation, Cholestenes, Female, Gonadotropins, Humans, Meiosis, Oocytes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
