Chondroitin sulfate E promotes neurite outgrowth of rat embryonic day 18 hippocampal neurons

The Molecular Biology of Axon Guidance

Tessier‐Lavigne, M., & Goodman, C. S. (1996) · Science · doi:10.1126/science.274.5290.1123 · Cited by 3,311

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

Serafini, T., Kennedy, T. E., Gaiko, M. J., Mirzayan, C., Jessell, T., & Tessier-Lavigne, M. (1994) · Cell · doi:10.1016/0092-8674(94)90420-0 · Cited by 1,397

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.

Keino-Masu, K., Masu, M., Hinck, L., Leonardo, E., Chan, S., Culotti, J., & Tessier-Lavigne, M. (1996) · Cell · doi:10.1016/s0092-8674(00)81336-7 · Cited by 1,048

Regeneration of adult axons in white matter tracts of the central nervous system

Davies, S. J. A., Fitch, M. T., Memberg, S. P., Hall, A. K., Raisman, G., & Silver, J. (1997) · Nature · doi:10.1038/37776 · Cited by 737

Chondroitin Sulfate as a Regulator of Neuronal Patterning in the Retina

Brittis, P. A., Canning, D. R., & Silver, J. (1992) · Science · doi:10.1126/science.1738848 · Cited by 415

Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties.

Faissner, A., Clement, A. M., Lochter, A., Streit, A., Mandl, C., & Schachner, M. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.126.3.783 · Cited by 354

Interactions of developing neurons with the extracellular matrix

Letourneau, P. C., Condic, M., & Snow, D. M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-00915.1994 · Cited by 304

Cadherins in the Developing Central Nervous System: An Adhesive Code for Segmental and Functional Subdivisions

Redies, C., & Takeichi, M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0315 · Cited by 247

Developmental Regulation of the Sulfation Profile of Chondroitin Sulfate Chains in the Chicken Embryo Brain

Kitagawa, H., Tsutsumi, K., Tone, Y., & Sugahara, K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.50.31377 · Cited by 187

Structure/function relationships of axon-associated adhesion receptors of the immunoglobulin superfamily

Brümmendorf, T., & Rathjen, F. G. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80089-4 · Cited by 175

The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system

Galtrey, C. M., & Fawcett, J. W. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.09.006 · Cited by 575

Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans

Sugahara, K., & Kitagawa, H. (2000) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(00)00125-1 · Cited by 423

Composition of Perineuronal Net Extracellular Matrix in Rat Brain

Deepa, S. S., Carulli, D., Galtrey, C., Rhodes, K., Fukuda, J., Mikami, T., Sugahara, K., & Fawcett, J. W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600544200 · Cited by 367

Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors

Deepa, S. S., Umehara, Y., Higashiyama, S., Itoh, N., & Sugahara, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207105200 · Cited by 335

Chondroitin 6‐sulphate synthesis is up‐regulated in injured CNS, induced by injury‐related cytokines and enhanced in axon‐growth inhibitory glia

Properzi, G., Carulli, D., Asher, R. A., Muir, E. M., Camargo, L. M., Kuppevelt, T. H. V., ten Dam, G. B., Furukawa, Y., Mikami, T., Sugahara, K., et al. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03876.x · Cited by 190

Diversity and functions of glycosaminoglycan sulfotransferases

Habuchi, O. (2000) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(00)00016-7 · Cited by 173

Proteoglycans in the central nervous system: Plasticity, regeneration and their stimulation with chondroitinase ABC

Kwok, J. C. F., Afshari, F. T., García‐Alías, G., & Fawcett, J. W. (2008) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2008-00439 · Cited by 170

CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension

Gilbert, R. J., McKeon, R. J., Darr, A., Calabro, A. R., Hascall, V., & Bellamkonda, R. V. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.04.006 · Cited by 172

Chondroitin Sulfate Proteoglycans in the Nervous System: Inhibitors to Repair

Siebert, J. R., Conta, A. C., & Osterhout, D. J. (2014) · BioMed Research International · doi:10.1155/2014/845323 · Cited by 159

Recent advance in delivery system and tissue engineering applications of chondroitin sulfate

Yang, J., Shen, M., Wen, H., Luo, Y. F., Huang, R., Rong, L., & Xie, J. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115650 · Cited by 156

Neuronal Cell Adhesion, Mediated by the Heparin-binding Neuroregulatory Factor Midkine, Is Specifically Inhibited by Chondroitin Sulfate E

Ueoka, C., Kaneda, N., Okazaki, I., Nadanaka, S., Muramatsu, T., & Sugahara, K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002538200 · Cited by 137

Role of the Sulfation Pattern of Chondroitin Sulfate in its Biological Activities and in the Binding of Growth Factors

Nandini, C., & Sugahara, K. (2006) · Advances in pharmacology · doi:10.1016/s1054-3589(05)53012-6 · Cited by 132

Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-E

Mikami, T., Yasunaga, D., & Kitagawa, H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m809227200 · Cited by 124

Oversulfated Dermatan Sulfate Exhibits Neurite Outgrowth-promoting Activity toward Embryonic Mouse Hippocampal Neurons

Hikino, M., Mikami, T., Faissner, A., Vilela-Silva, A.-C. E. S., Pavão, M. S. G., & Sugahara, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308169200 · Cited by 126

Structural and Functional Characterization of Oversulfated Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from the Notochord of Hagfish

Nandini, C., Mikami, T., Ohta, M., Itoh, N., Akiyama-Nambu, F., & Sugahara, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404746200 · Cited by 123

6-Sulphated Chondroitins Have a Positive Influence on Axonal Regeneration

Lin, R., Rosahl, T. W., Whiting, P. J., Fawcett, J. W., & Kwok, J. C. F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021499 · Cited by 121

Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide library

Ito, Y., Hikino, M., Yajima, Y., Mikami, T., Sirko, S., von Holst, A., Faissner, A., Fukui, S., & Sugahara, K. (2004) · Glycobiology · doi:10.1093/glycob/cwi036 · Cited by 116

Human N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase cDNA Is Related to Human B Cell Recombination Activating Gene-associated Gene

Ohtake, S., Ito, Y., Fukuta, M., & Habuchi, O. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104922200 · Cited by 109

Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches

Rogers, C. J., Clark, P. M., Tully, S. E., Abrol, R., García, K. C., Goddard, W. A., & Hsieh‐Wilson, L. C. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102962108 · Cited by 116

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

Menezes, R., Vincent, R., Osorno, L., Hu, P., & Arinzeh, T. L. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.09.064 · Cited by 121

Novel 70-kDa Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains with a Unique Heterogenous Sulfation Pattern from Shark Skin, Which Exhibit Neuritogenic Activity and Binding Activities for Growth Factors and Neurotrophic Factors

Nandini, C., Itoh, N., & Sugahara, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412074200 · Cited by 107

Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Embryonic Pig Brain, Which Contain a Higher Proportion of L-Iduronic Acid than Those from Adult Pig Brain, Exhibit Neuritogenic and Growth Factor Binding Activities

Bao, X., Nishimura, S., Mikami, T., Yamada, S., Itoh, N., & Sugahara, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310877200 · Cited by 108

From barriers to bridges: chondroitin sulfate proteoglycans in neuropathology

Viapiano, M. S., & Matthews, R. T. (2006) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2006.08.007 · Cited by 103

Chondroitin Sulfate “Wobble Motifs” Modulate Maintenance and Differentiation of Neural Stem Cells and Their Progeny

Purushothaman, A., Sugahara, K., & Faissner, A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.298430 · Cited by 104

Sugar-dependent modulation of neuronal development, regeneration, and plasticity by chondroitin sulfate proteoglycans

Miller, G. M., & Hsieh‐Wilson, L. C. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.08.015 · Cited by 101

Heparin-binding Growth Factor, Pleiotrophin, Mediates Neuritogenic Activity of Embryonic Pig Brain-derived Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains

Bao, X., Mikami, T., Yamada, S., Faissner, A., Muramatsu, T., & Sugahara, K. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413423200 · Cited by 89

Overcoming neurite‐inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix

Cua, R. C., Lau, L. W., Keough, M. B., Midha, R., Apte, S., & Yong, V. W. (2013) · Glia · doi:10.1002/glia.22489 · Cited by 90

DSD-1-Proteoglycan/Phosphacan and receptor protein tyrosine phosphatase-beta isoforms during development and regeneration of neural tissues.

Faissner, A., Heck, N., Dobbertin, A., & Garwood, J. (2006) · Advances in Experimental Medicine and Biology · doi:10.1007/0-387-30128-3_3 · Cited by 88

Functional Analysis of the Chondroitin 6-Sulfotransferase Gene in Relation to Lymphocyte Subpopulations, Brain Development, and Oversulfated Chondroitin Sulfates

Uchimura, K., Kadomatsu, K., Nishimura, H., Muramatsu, H., Nakamura, E., Kurosawa, N., Habuchi, O., El-Fasakhany, F. M., Yoshikai, Y., & Muramatsu, T. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m104719200 · Cited by 86

Inhibition of Axon Growth by Oligodendrocyte Precursor Cells

Chen, Z. J., Ughrin, Y., & Levine, J. M. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1102 · Cited by 86

Using glyco-engineering to produce therapeutic proteins

Dicker, M., & Strasser, R. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1069271 · Cited by 73

Activation of phospholipase C pathways by a synthetic chondroitin sulfate‐E tetrasaccharide promotes neurite outgrowth of dopaminergic neurons

Sotogaku, N., Tully, S. E., Gama, C. I., Higashi, H., Tanaka, M., Hsieh‐Wilson, L. C., & Nishi, A. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04849.x · Cited by 79

Functions of Chondroitin Sulfate/Dermatan Sulfate Chains in Brain Development

Purushothaman, A., Fukuda, J., Mizumoto, S., ten Dam, G. B., Kuppevelt, T. H. V., Kitagawa, H., Mikami, T., & Sugahara, K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700630200 · Cited by 82

Glycan Engineering for Cell and Developmental Biology

Griffin, M. E., & Hsieh‐Wilson, L. C. (2016) · Cell chemical biology · doi:10.1016/j.chembiol.2015.12.007 · Cited by 77

Structural Characterization of Heparan Sulfate and Chondroitin Sulfate of Syndecan-1 Purified from Normal Murine Mammary Gland Epithelial Cells

Ueno, M., Yamada, S., Zako, M., Bernfield, M. R., & Sugahara, K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102089200 · Cited by 75

Increased processing of APLP2 and APP with concomitant formation of APP intracellular domains in BDNF and retinoic acid‐differentiated human neuroblastoma cells

Holback, S., Adlerz, L., & Iverfeldt, K. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03440.x · Cited by 72

Flexible Roles for Proteoglycan Sulfation and Receptor Signaling

Yu, P., Pearson, C. S., & Geller, H. M. (2018) · Trends in Neurosciences · doi:10.1016/j.tins.2017.10.005 · Cited by 67

NMR Chemical Shifts in Structural Biology of Glycosaminoglycans

Pomin, V. H. (2013) · Analytical Chemistry · doi:10.1021/ac401791h · Cited by 66

Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes

Deepa, S. S., Yamada, S., Fukui, S., & Sugahara, K. (2007) · Glycobiology · doi:10.1093/glycob/cwm021 · Cited by 65

Domain Structure of Chondroitin Sulfate E Octasaccharides Binding to Type V Collagen

Takagaki, K., Munakata, H., Kakizaki, I., Iwafune, M., Itabashi, T., & Endo, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106479200 · Cited by 66

Demonstration of the Pleiotrophin-binding Oligosaccharide Sequences Isolated from Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains of Embryonic Pig Brains

Bao, X., Muramatsu, T., & Sugahara, K. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507304200 · Cited by 67

Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains in the Development of Cerebellum

Mitsunaga, C., Mikami, T., Mizumoto, S., Fukuda, J., & Sugahara, K. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m510870200 · Cited by 64

Role of Chondroitin Sulfation Following Spinal Cord Injury

Hussein, R. K., Mencio, C. P., Katagiri, Y., Brake, A., & Geller, H. M. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00208 · Cited by 60

Semi-synthesis of chondroitin sulfate-E from chondroitin sulfate-A

Cai, C., Solakyildirim, K., Yang, B., Beaudet, J. M., Weyers, A. M., Linhardt, R. J., & Zhang, F. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.08.075 · Cited by 57

Appican, the Proteoglycan Form of the Amyloid Precursor Protein, Contains Chondroitin Sulfate E in the Repeating Disaccharide Region and 4-O-Sulfated Galactose in the Linkage Region

Tsuchida, K., Shioi, J., Yamada, S., Boghosian, G., Wu, A., Cai, H., Sugahara, K., & Robakis, N. K. R. K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105818200 · Cited by 55

Structural Determination of Five Novel Tetrasaccharides Containing 3-O-Sulfated d -Glucuronic Acid and Two Rare Oligosaccharides Containing a β- d -Glucose Branch Isolated from Squid Cartilage Chondroitin Sulfate E

Kinoshita‐Toyoda, A., Yamada, S., Haslam, S. M., Khoo, K., Sugiura, M., Morris, H. R., Dell, A., & Sugahara, K. (2004) · Biochemistry · doi:10.1021/bi049622d · Cited by 54

Isolation and Structural Determination of Novel Sulfated Hexasaccharides from Squid Cartilage Chondroitin Sulfate E That Exhibits Neuroregulatory Activities

Kinoshita, A., Yamada, S., Haslam, S. M., Morris, H. R., Dell, A., & Sugahara, K. (2001) · Biochemistry · doi:10.1021/bi015577n · Cited by 53

Targeted downregulation of N‐acetylgalactosamine 4‐sulfate 6‐O‐sulfotransferase significantly mitigates chondroitin sulfate proteoglycan‐mediated inhibition

Karumbaiah, L., Anand, S., Thazhath, R., Zhong, Y., McKeon, R. J., & Bellamkonda, R. V. (2011) · Glia · doi:10.1002/glia.21170 · Cited by 53

Biosynthesis of Glycosaminoglycans and Proteoglycans

Uyama, T., Kitagawa, H., & Sugahara, K. (2007) · Elsevier eBooks · doi:10.1016/b978-044451967-2/00036-2 · Cited by 54

A Functional Dermatan Sulfate Epitope Containing Iduronate(2-O-sulfate)α1–3GalNAc(6-O-sulfate) Disaccharide in the Mouse Brain

Bao, X., Pavão, M. S. G., dos Santos, J. C., & Sugahara, K. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503036200 · Cited by 50

Purification and Characterization ofN-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase from the Squid Cartilage

Ito, Y., & Habuchi, O. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909633199 · Cited by 50

Harnessing chondroitin sulphate in composite scaffolds to direct progenitor and stem cell function for tissue repair

Farrugia, B. L., Lord, M. S., Whitelock, J. M., & Melrose, J. (2018) · Biomaterials Science · doi:10.1039/c7bm01158j · Cited by 46

A highly sulfated chondroitin sulfate preparation, CS‐E, prevents excitatory amino acid‐induced neuronal cell death

Sato, Y., Nakanishi, K., Tokita, Y., Kakizawa, H., Ida‐Eto, M., Maeda, H. A., Matsui, F., Aono, S., Saito, A. M., Kuroda, Y., et al. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05107.x · Cited by 49

The Glial Response to Injury and Its Role in the Inhibition of CNS Repair

Fawcett, J. W. (2007) · Springer eBooks · doi:10.1007/0-387-30128-3_2 · Cited by 46

Role of Extracellular Factors in Axon Regeneration in the CNS: Implications for Therapy

Gervasi, N. M., Kwok, J. C. F., & Fawcett, J. W. (2008) · Regenerative Medicine · doi:10.2217/17460751.3.6.907 · Cited by 42

Enzymatic synthesis of chondroitin sulfate E by N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase purified from squid cartilage

Habuchi, O., Moroi, R., & Ohtake, S. (2002) · Analytical Biochemistry · doi:10.1016/s0003-2697(02)00277-4 · Cited by 42

Mice Deficient in N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase Are Unable to Synthesize Chondroitin/Dermatan Sulfate containing N-Acetylgalactosamine 4,6-Bissulfate Residues and Exhibit Decreased Protease Activity in Bone Marrow-derived Mast Cells

Ohtake‐Niimi, S., Kondo, S., Ito, T., Kakehi, S., Ohta, T., Habuchi, H., Kimata, K., & Habuchi, O. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.084749 · Cited by 45

Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences Recognized by Monoclonal Antibody WF6

Pothacharoen, P., Kalayanamitra, K., Deepa, S. S., Fukui, S., Hattori, T., Fukushima, N., Hardingham, T., Kongtawelert, P., & Sugahara, K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702255200 · Cited by 41

Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain

Akatsu, C., Mizumoto, S., Kaneiwa, T., Maccarana, M., Malmström, A., Yamada, S., & Sugahara, K. (2010) · Glycobiology · doi:10.1093/glycob/cwq208 · Cited by 38

A novel chondroitin sulfate E from Dosidicus gigas cartilage and its antitumor metastatic activity

Peng, C., Wang, Q., Jiao, R., Xu, Y., Han, N., Wang, W., Zhu, C., & Li, F. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.117971 · Cited by 36

Small interfering RNA therapy against carbohydrate sulfotransferase 15 inhibits cardiac remodeling in rats with dilated cardiomyopathy

Watanabe, K., Arumugam, S., Sreedhar, R., Thandavarayan, R. A., Nakamura, T., Nakamura, M., Harima, M., Yoneyama, H., & Suzuki, K. (2015) · Cellular Signalling · doi:10.1016/j.cellsig.2015.03.004 · Cited by 33

Role of Region-Specific Brain Decellularized Extracellular Matrix on In Vitro Neuronal Maturation

Reginensi, D., Ortiz, D. A., Pravia, A., Burillo, A., Morales, F. L., Morgan, C., Jimenez, L., Dave, K. R., Pérez‐Pinzón, M. A., & Gittens, R. A. (2020) · Tissue Engineering Part A · doi:10.1089/ten.tea.2019.0277 · Cited by 35

Role of GalNAc4S-6ST in Astrocytic Tumor Progression

Kobayashi, T., Yan, H., Kurahashi, Y., Ito, Y., Maeda, H. A., Tada, T., Hongo, K., & Nakayama, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054278 · Cited by 34

Recognition of Sulfation Pattern of Chondroitin Sulfate by Uronosyl 2-O-Sulfotransferase

Ohtake, S., Kimata, K., & Habuchi, O. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508816200 · Cited by 34

Investigation of glycosaminoglycan mimetic scaffolds for neurite growth

Menezes, R., Hashemi, S., Vincent, R., Collins, G. L., Meyer, J., Foston, M. B., & Arinzeh, T. L. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.03.024 · Cited by 33

Structure of Pleiotrophin- and Hepatocyte Growth Factor-binding Sulfated Hexasaccharide Determined by Biochemical and Computational Approaches

Li, F., Nandini, C., Hattori, T., Bao, X., Murayama, D., Nakamura, T., Fukushima, N., & Sugahara, K. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.118703 · Cited by 33

Chondroitin sulfate-D promotes neurite outgrowth by acting as an extracellular ligand for neuronal integrin αVβ3

Shida, M., Mikami, T., Tamura, J.-I., & Kitagawa, H. (2019) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2019.06.004 · Cited by 31

Development of affinity-based delivery of NGF from a chondroitin sulfate biomaterial

Butterfield, K. C., Conovaloff, A. W., & Panitch, A. (2011) · Biomatter · doi:10.4161/biom.18791 · Cited by 31

Chondroitin sulfate of appican, the proteoglycan form of amyloid precursor protein, produced by C6 glioma cells interacts with heparin‐binding neuroregulatory factors

Umehara, Y., Yamada, S., Nishimura, S., Shioi, J., Robakis, N. K. R. K., & Sugahara, K. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01506-0 · Cited by 31

Chondroitin sulfate-binding peptides block chondroitin 6-sulfate inhibition of cortical neurite growth

Butterfield, K. C., Conovaloff, A. W., Caplan, M. R., & Panitch, A. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.04.070 · Cited by 31

Developmental changes in the biochemical and immunological characters of the carbohydrate moiety of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan

Shuo, T., Aono, S., Matsui, F., Tokita, Y., Maeda, H. A., Shimada, K., & Oohira, A. (2003) · Glycoconjugate Journal · doi:10.1023/b:glyc.0000025821.22618.33 · Cited by 31

Differential expression of phosphacan/RPTPβ isoforms in the developing mouse visual system

Klausmeyer, A., Garwood, J., & Faissner, A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21479 · Cited by 28

Coating of polyurethane scaffolds with collagen: comparison of coating and cross-linking techniques

Douglas, T., & Haugen, H. J. (2008) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-008-3393-6 · Cited by 27

Chondroitin Sulfate Promotes the Proliferation of Keloid Fibroblasts Through Activation of the Integrin and Protein Kinase B Pathways

Katayama, Y., Naitoh, M., KUBOTA, H. Y., Yamawaki, S., Aya, R., Ishiko, T., & Morimoto, N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21061955 · Cited by 24

Isolation and characterization of a novel chondroitin sulfate from squid liver integument rich in N-acetylgalactosamine(4,6-disulfate) and glucuronate(3-sulfate) residues

Shetty, A. K., Kobayashi, T., Mizumoto, S., 鳴海正樹, Kudo, Y., Yamada, S., & Sugahara, K. (2009) · Carbohydrate Research · doi:10.1016/j.carres.2009.02.029 · Cited by 26

Corneal Sulfated Glycosaminoglycans and Their Effects on Trigeminal Nerve Growth Cone Behavior In Vitro: Roles for ECM in Cornea Innervation

Schwend, T., Deaton, R., Zhang, Y., Caterson, B., & Conrad, G. W. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-10832 · Cited by 24

A characteristic chondroitin sulfate trisaccharide unit with a sulfated fucose branch exhibits neurite outgrowth-promoting activity: Novel biological roles of fucosylated chondroitin sulfates isolated from the sea cucumber Apostichopus japonicus

Shida, M., Mikami, T., Tamura, J., & Kitagawa, H. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.04.114 · Cited by 23

Neuroglycan C, a brain-specific part-time proteoglycan, with a particular multidomain structure

Oohira, A., Shuo, T., Tokita, Y., Nakanishi, K., & Aono, S. (2004) · Glycoconjugate Journal · doi:10.1023/b:glyc.0000043748.90896.83 · Cited by 23

The Utility of Formalin-fixed and Paraffin-embedded Tissue Blocks for Quantitative Analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA Expressed by Colorectal Cancer Cells

Ito, Y., Watanabe, M., Nishizawa, T., Omachi, T., Kobayashi, T., Kasama, S., Habuchi, O., & Nakayama, J. (2007) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.07004 · Cited by 21

Glycans in Diseases and Therapeutics

Pavão, M. S. G. (2011) · Springer eBooks · doi:10.1007/978-3-642-16833-8 · Cited by 22

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase expression during early mouse embryonic development

Salgueiro, A. M., Filipe, M., & Belo, J. A. (2006) · The International Journal of Developmental Biology · doi:10.1387/ijdb.062168as · Cited by 21

Chondroitin sulfate, a major component of the perineuronal net, elicits inward currents, cell depolarization, and calcium transients by acting on AMPA and kainate receptors of hippocampal neurons

Maroto, M., Fernández‐Morales, J., Padín, J. F., Gonzalez, J., Hernández-Guijo, J. M., Montell, E., Vergés, J., de Diego, A. M. G., & de Diego, A. M. G. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12159 · Cited by 19

Chondroitin sulfate E alleviates β-amyloid toxicity in transgenic Caenorhabditis elegans by inhibiting its aggregation

Wang, X., Yang, Y., Zou, J., Li, Y., & Zhang, X. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.04.124 · Cited by 19

A chondroitin sulfate and hyaluronic acid lyase with poor activity to glucuronyl 4,6-O-disulfated N-acetylgalactosamine (E-type)–containing structures

Peng, C., Wang, Q., Wang, S., Wang, W., Jiao, R., Han, W., & Li, F. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra117.001238 · Cited by 19

Modeling large protein–glycosaminoglycan complexes using a fragment‐based approach

Samsonov, S. A., Zacharias, M., & de Beauchêne, I. C. (2019) · Journal of Computational Chemistry · doi:10.1002/jcc.25797 · Cited by 18

Perineuronal net deglycosylation associates with tauopathy‐induced gliosis and neurodegeneration

Logsdon, A. F., Foresi, B., Hu, S. J., Quah, E., Meuret, C. J., Le, J. P., Hendrickson, A. S., Redford, I. K., Kumar, A., Phan, B. A., et al. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16067 · Cited by 16

Functions of chondroitin/dermatan sulfate containing GalNAc4,6-disulfate

Habuchi, O. (2022) · Glycobiology · doi:10.1093/glycob/cwac030 · Cited by 16

Identification of chondroitin/dermatan sulfotransferases in the protochordate, Ciona intestinalis

Tetsukawa, A., Nakamura, J., & Fujiwara, S. (2010) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2010.06.009 · Cited by 16

Chondroitin Sulfate Induces Depression of Synaptic Transmission and Modulation of Neuronal Plasticity in Rat Hippocampal Slices

Albiñana, E., Luengo, J. G., Juárez, N. H., Baraibar, A. M., Montell, E., Vergés, J., Garcı́a, A. G., & Hernández-Guijo, J. M. (2015) · Neural Plasticity · doi:10.1155/2015/463854 · Cited by 14

Synthesis of sulfated phenyl 2-acetamido-2-deoxy-D-galactopyranosides. 4-O-Sulfated phenyl 2-acetamido-2-deoxy-β-D-galactopyranoside is a competitive acceptor that decreases sulfation of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

Sawada, T., Fujii, S., Nakano, H., Ohtake, S., Kimata, K., & Habuchi, O. (2005) · Carbohydrate Research · doi:10.1016/j.carres.2005.06.010 · Cited by 14

Selective inhibition of ventral temporal but not dorsal nasal neurites from mouse retinal explants during contact with chondroitin sulphate

Cheung, A. W. S., Lam, J. S. Y., & Chan, S. O. (2005) · Cell and Tissue Research · doi:10.1007/s00441-005-1104-x · Cited by 13

Moderate repulsive effects of E-unit-containing chondroitin sulfate (CSE) on behavior of retinal growth cones

Shimbo, M., Ando, S., Sugiura, N., Kimata, K., & Ichijo, H. (2012) · Brain Research · doi:10.1016/j.brainres.2012.11.011 · Cited by 12

Molecular Cloning of Squid N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase and Synthesis of a Unique Chondroitin Sulfate Containing E D Hybrid Tetrasaccharide Structure by the Recombinant Enzyme

Yamaguchi, T., Ohtake, S., Kimata, K., & Habuchi, O. (2007) · Glycobiology · doi:10.1093/glycob/cwm103 · Cited by 11

Structure and Biological Activities of Glycosaminoglycan Analogs from Marine Invertebrates: New Therapeutic Agents?

Kozlowski, E. O., Gomes, A. M., Silva, C. S., Pereira, M. S., Silva, A. C. E. S. D. V., & Pavão, M. S. G. (2011) · Springer eBooks · doi:10.1007/978-3-642-16833-8_7 · Cited by 11

Preparation of chondroitin sulfate libraries containing disulfated disaccharide units and inhibition of thrombin by these chondroitin sulfates

Numakura, M., Kusakabe, N., Ishige, K., Ohtake‐Niimi, S., Habuchi, H., & Habuchi, O. (2010) · Glycoconjugate Journal · doi:10.1007/s10719-010-9293-2 · Cited by 10

Inhibition of proteoglycan synthesis affects neuronal outgrowth and astrocytic migration in organotypic cultures of fetal ventral mesencephalon

Berglöf, E., Plantman, S., Johansson, S., & Strömberg, I. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21465 · Cited by 10

Redirection of Neurite Outgrowth by Coupling Chondroitin Sulfate Proteoglycans to Polymer Membranes

Man, A. J., Leach, J. K., & Bannerman, P. G. C. (2014) · Annals of Biomedical Engineering · doi:10.1007/s10439-014-0991-y · Cited by 9

A highly-sulfated chondroitin sulfate, CS-E, adsorbs specifically to neurons with nuclear condensation

Nakanishi, K., Ito, M., Sato, Y., & Oohira, A. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.08.009 · Cited by 9

Characterization of chondroitin sulfate from deer tip antler and osteogenic properties

Pothacharoen, P., Kodchakorn, K., & Kongtawelert, P. (2011) · Glycoconjugate Journal · doi:10.1007/s10719-011-9346-1 · Cited by 9

Knockout Mice and Proteoglycans

Kimata, K., Habuchi, O., Habuchi, H., & Watanabe, H. (2007) · Elsevier eBooks · doi:10.1016/b978-044451967-2/00087-8 · Cited by 10

Multifunctions of Sustainable Chondroitin Sulfates with Predominant Subtypes and Low Molecular Weights on Neurite Outgrowth

Xu, S., Qiu, M., Liang, L., Chen, Y., Wang, Y., Wu, J., & Chen, J. (2025) · Biomacromolecules · doi:10.1021/acs.biomac.4c01713 · Cited by 1

Differential effects of glycosaminoglycans on neurite outgrowth from hippocampal and thalamic neurones

Fernaud-Espinosa, I., Nieto‐Sampedro, M., & Bovolenta, P. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.6.1437 · Cited by 67

Core Protein of Chondroitin Sulfate Proteoglycan Promotes Neurite Outgrowth from Cultured Neocortical Neurons

Iijima, N., Oohira, A., Mori, T., Kitabatake, K., & Kohsaka, S. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb08207.x · Cited by 112

Oversulfated Dermatan Sulfate Exhibits Neurite Outgrowth-promoting Activity toward Embryonic Mouse Hippocampal Neurons

Hikino, M., Mikami, T., Faissner, A., Vilela-Silva, A.-C. E. S., Pavão, M. S. G., & Sugahara, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308169200 · Cited by 126

Evaluation of Chondroitin Sulfate Bioactivity in Hippocampal Neurones and the Astrocyte Cell Line U373: Influence of Position of Sulfate Groups and Charge Density

Rapp, A., Brandl, N., Volpi, N., & Huettinger, M. (2005) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2005.pto960106.x · Cited by 13