The DOI matches its Crossref record; 33 of the 36 references it cites were found in a registry or an index.
Virtual reality as an adjunctive pain control during burn wound care in adolescent patients
Abstract
For daily burn wound care procedures, opioid analgesics alone are often inadequate. Since most burn patients experience severe to excruciating pain during wound care, analgesics that can be used in addition to opioids are needed. This case report provides the first evidence that entering an immersive virtual environment can serve as a powerful adjunctive, nonpharmacologic analgesic. Two patients received virtual reality (VR) to distract them from high levels of pain during wound care. The first was a 16-year-old male with a deep flash burn on his right leg requiring surgery and staple placement. On two occasions, the patient spent some of his wound care in VR, and some playing a video game. On a 100 mm scale, he provided sensory and affective pain ratings, anxiety and subjective estimates of time spent thinking about his pain during the procedure. For the first session of wound care, these scores decreased 80 mm, 80 mm, 58 mm, and 93 mm, respectively, during VR treatment compared with the video game control condition. For the second session involving staple removal, scores also decreased. The second patient was a 17-year-old male with 33.5% total body surface area deep flash burns on his face, neck, back, arms, hands and legs. He had difficulty tolerating wound care pain with traditional opioids alone and showed dramatic drops in pain ratings during VR compared to the video game (e.g. a 47 mm drop in pain intensity during wound care). We contend that VR is a uniquely attention-capturing medium capable of maximizing the amount of attention drawn away from the 'real world', allowing patients to tolerate painful procedures. These preliminary results suggest that immersive VR merits more attention as a potentially viable form of treatment for acute pain.
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“VR is so attention grabbing that it is being used to distract severe burn patients from their pain during severe burn wound cleaning, and burn patients report large reductions in the amount of time they spend thinking about their pain during painful medical procedures [22–25].”
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Sampling Electrocardiography Confirmation for a Virtual Reality Pain Management Tool
Matsangidou, M., Mauger, A. R., Ang, C. S., & Pattichis, C. S. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-49698-2_27 · Cited by 2
Turbyne, C., de Koning, P. P., Smit, D. J. A., & Denys, D. A. J. P. (2021) · Frontiers in Virtual Reality · doi:10.3389/frvir.2021.694511 · Cited by 2
“…competing theories attempting to explain the analgesic potential of virtual reality postulates that virtual reality is able to effectively distract an individual from noxious stimuli (Hoffman et al., 2000; Hoffman et al., 2001; Schneider et al., 2004; Gershon et al., 2004; Hoffman et al., 2011).”
BackgroundBoyun Ağrısı Tedavisinde Sanal Gerçeklik Uygulamaları
Korkmaz, B. E., & Şengül, Y. S. (2023) · Türkiye Sağlık Bilimleri ve Araştırmaları Dergisi · doi:10.51536/tusbad.1150411 · Cited by 2
Virtual Reality in Higher Education: A Case Study at the Air University's Squadron Officer College
Millican, T. (2017) · Cited by 2
Uses of Virtual Reality (VR) for Chronic Pain
Chi, B., Chau, B., & Ta, P. A. (2018) · Advances in psychology, mental health, and behavioral studies (APMHBS) book series · doi:10.4018/978-1-5225-7168-1.ch013 · Cited by 2
Virtual Reality Therapy for Acute/Procedural Pain
Frey, D. P., & Sharar, S. R. (2018) · Springer eBooks · doi:10.1007/978-3-319-95369-4_29 · Cited by 2
Automating Pain Reduction Using Biosensors and Realtime Adaptive VR
Bondin, L., & Dingli, A. (2020) · Advances in computational intelligence and robotics book series · doi:10.4018/978-1-7998-3499-1.ch008 · Cited by 2
Virtual Reality Distraction Analgesia
Sharar, S. R. (2006) · Cited by 2
Gorini, A. (2010) · Research Publications (Maastricht University) · doi:10.26481/dis.20100922ag · Cited by 2
The development of exhaled breath condensate: a noninvasive method of measuring airway inflammation
Rosias, P. P. R. (2008) · doi:10.26481/dis.20080214pr · Cited by 2
Sharar, S. R., Patterson, D. R., & Askay, S. W. (2007) · Elsevier eBooks · doi:10.1016/b978-0-7216-0334-6.50025-x · Cited by 2
Massov, L. (2021) · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare) · doi:10.26686/wgtn.17125649 · Cited by 3
The top 100 cited papers on mental health and virtual reality: a bibliometric analysis
Guan, Y., Wang, Y., Zhuang, D., Wei, W., Ma, L., Du, H., Fan, C. G., & Li, X. (2025) · Psychology Health & Medicine · doi:10.1080/13548506.2025.2460336 · Cited by 1
“VR has found applications in various fields, including education (Mikropoulos & Natsis, 2011), training (Ahlberg et al., 2007), healthcare (Hoffman et al., 2000), tourism (Guttentag, 2010), construction (Li et al., 2018), and games (McMahan et al., 2012), among others.”
Design and Evaluation of Pseudo-Haptic Techniques for Simulating Surface Stickiness in VR
Hirao, Y., Bourse, C., Hori, K., Narumi, T., Argelaguet, F., & Lécuyer, A. (2025) · Proceedings - International Symposium on Mixed and Augmented Reality, ISMAR · doi:10.1109/ismar67309.2025.00108 · Cited by 1
“Similar attention-diversion principles underlie pain-reduction studies that modulate sensory experience by shifting focus [18, 29, 16].”
Constantinescu, G.-G., & Iftene, A. (2025) · International Conference on Innovations in Intelligent Systems and Applications (INISTA) · doi:10.1109/inista68122.2025.11249661 · Cited by 1
“Several studies have highlighted the therapeutic benefits of VR-based exposure therapy in treating anxiety disorders and phobias [1], [2].”
Fontenot, M. R., Curatolo, M., Stacey, B. R., Flor, H., & Hoffman, H. G. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1622897 · Cited by 1
“The first published VR analgesia study (14) used a $90,000 USD VR system to distract burn patients during wound cleaning.”
Self-citationHealing-Oriented Patient-Centered Care in the Healthcare Environment
Liu, Y., Deng, Y., Feng, H., Liu, Z., & Osmani, M. (2026) · Buildings · doi:10.3390/buildings16030507 · Cited by 1
Metadata
- Authors
- Hoffman, H. G., Doctor, J. N., Patterson, D. R., Carrougher, G. J., & Furness, T. A.
- Affiliations
- University of Washington (US)
- Corresponding author
- Patterson, David R.
- Venue
- Pain
- Published
- 2000-03-01
- Volume
- 85
- Issue
- 1
- Pages
- 305-309
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2034120147
- Cited by
- 651
- References
- 36
- Citations by year
- 2026: 30 · 2025: 29 · 2024: 43 · 2023: 46 · 2022: 42 · 2021: 50 · 2020: 46 · 2019: 31 · 2018: 31 · 2017: 30 · 2016: 19 · 2015: 15 · 2014: 30 · 2013: 11 · 2012: 20
- FWCI
- 14.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of General Medical Sciences (GM42725-07, R01GM042725)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Health Sciences › Medicine › Surgery › Burn Injury Management and Outcomes
- Keywords
- virtual reality, burn wound care, procedural pain, distraction therapy, non-pharmacological analgesia, adolescents, opioid analgesics, pain intensity, anxiety, video games, staple removal, acute pain management
- MeSH terms
- Adolescent, Burns, Computer Graphics, Humans, Male, Pain, Pain Measurement, User-Computer Interface, Pain Management
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