Anthelmintic activity of essential oil of Ocimum sanctum and eugenol
Abstract
The essential oil of Ocimum sanctum and eugenol, tested in vitro, showed potent anthelmintic activity in the Caenorhabditis elegans model. Eugenol exhibited an ED(50) of 62.1 microg/ml. Eugenol being the predominant component of the essential oil, is suggested as the putative anthelmintic principle.
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Eugenol is widely known for its healing properties, including antimicrobial and anti-inflammatory effects.
“Eugenol is widely known for its healing properties, consisting of antimicrobial and anti-inflammatory effects [22,23,24] .”
From Untargeted metabolomics and targeted approach of essential oils to differentiate five Ocimum species using gas chromatography coupled with mass spectrometry (2024) · cites this paper as [22]
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Essential oil eugenol: Sources, extraction techniques and nutraceutical perspectives
Khalil, A. A., Rahman, U. U., Khan, M. R., Sahar, A., Mehmood, T., & Khan, M. (2017) · RSC Advances · doi:10.1039/c7ra04803c · Cited by 407 · see citing works
A review on phytochemical and pharmacological properties of holy basil (Ocimum sanctum L.)
Singh, D., & Chaudhuri, P. K. (2018) · Industrial Crops and Products · doi:10.1016/j.indcrop.2018.03.048 · Cited by 218 · see citing works
Phenylpropanoids, eugenol scaffold, and its derivatives as anticancer
Fadilah, F., Yanuar, A., Arsianti, A., & Andrajati, R. (2017) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2017.v10i3.16071 · Cited by 28 · see citing works
Jaiswal, R. P., Pasrija, A., Mishra, B., Gupta, P. K., & Mitra, R. (2024) · The Journal of Phytopharmacology · doi:10.31254/phyto.2024.13602 · Cited by 2 · see citing works
- Authors
- Asha, M. K., Prashanth, D., Murali, B., Padmaja, R., & Amit, A.
- Affiliations
- Natural Remedies (India) (IN)
- Corresponding author
- Prashanth, D.
- ORCID
- Murali, B.
- Venue
- Fitoterapia
- Publisher
- Elsevier BV
- Published
- 2001-08
- Volume
- 72
- Issue
- 6
- Pages
- 669-670
- ISSN
- 0367-326X (ISSN-L)
- OpenAlex
- W1973357027
- Cited by
- 151
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 7 · 2023: 7 · 2022: 8 · 2021: 13 · 2020: 4 · 2019: 8 · 2018: 4 · 2017: 7 · 2016: 4 · 2015: 9 · 2014: 12 · 2013: 11 · 2012: 8
- FWCI
- 4.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Fitoterapia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Insect Pest Control Strategies
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Keywords
- anthelmintic activity, Ocimum sanctum, essential oils, eugenol, Caenorhabditis elegans, in vitro antiparasitic activity
- MeSH terms
- Animals, Antinematodal Agents, Eugenol, Humans, Oils, Volatile, Plant Oils, Caenorhabditis elegans, Ocimum basilicum, Parasitic Sensitivity Tests
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