Cited by 283Cardiovascular Syncope and Autonomic DisordersNeurological and metabolic disordersCardiovascular and Diving-Related Complications

Syncope in Children and Adolescents

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Driscoll, David J, Jacobsen, Steven J, Porter, Co-burn J, Wollan, Peter C·1997·Journal of the American College of Cardiology

Abstract

Objectives The objectives of this study were to 1) define the incidence of syncope coming to medical attention among children and adolescents, 2) determine the outcome of syncope in these patients, and 3) determine changes over time in the evaluation and charges for evaluating this problem. Background Syncope occurs commonly in children and adolescents. However, the mid- and long-term outcome of children and adolescents who experience syncope is unknown. Methods Utilizing the Rochester Epidemiology Project, we determined the incidence, outcome and charges for medical evaluation for patients seeking medical attention for syncope during an early 5-year period (1950 to 1954) and a more recent 5-year period (1987 to 1991). Results The incidence of syncope coming to medical attention was 71.9 and 125.8/100,000 population for the early and more recent cohort, respectively. The incidence was higher for female than for male patients. The incidence peaked in 15- to 19-year old patients. Acute illness and noxious stimuli were associated with 24% and 23% of the episodes, respectively. Although long-term survival was not different from that of the general population, one child died suddenly, and another had hereditary prolonged QT interval syndrome. These were two of only six patients who had exertional syncope. Total charges for evaluation of syncope were similar in the two time periods. However, charges for testing procedures were greater for the more recent cohort. Conclusions In general, syncope in children and adolescents is a benign event. Syncope occurring during exercise may identify patients with a potentially fatal condition. Detailed evaluation should be considered for patients who have syncope during exercise or who have a family history of syncope, sudden death, myocardial disease or arrhythmias. It may be prudent to obtain an electrocardiogram for all patients who seek medical attention for syncope.

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  • By 18 years of age, an estimated 30% to 50% of children experience at least 1 fainting episode.

    “By 18 years of age, it is estimated that 30% to 50% of children experience at least 1 fainting episode, and syncope accounts for 3% of all pediatric ED visits (617–622).”

    From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [617]

    The Abstract says syncope is common in children and adolescents, and the Results report incidence of episodes coming to medical attention. Neither passage gives an estimate that 30% to 50% of children have fainted by age 18; incidence of medically attended episodes does not establish that lifetime proportion. (LLM, conf=0.78)

    Experimental — accuracy not yet measured
  • The incidence of pediatric syncope is higher in females and peaks between 15 to 19 years of age.

    “The incidence is higher in females and peaks between 15 to 19 years of age (617).”
  • Syncope accounts for 3% of all pediatric ED visits.

    “By 18 years of age, it is estimated that 30% to 50% of children experience at least 1 fainting episode, and syncope accounts for 3% of all pediatric ED visits (617–622).”

    From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [617]

    The Abstract reports the incidence of syncope coming to medical attention, while “Syncope in children” discusses children evaluated in an emergency room for syncope. Neither gives syncope as a proportion of all pediatric ED visits. Searches for the 3% figure and for emergency-room visit proportions found no supporting passage in our copy. (LLM, conf=0.73)

    Experimental — accuracy not yet measured

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Cites

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Research works printed but not linked: 6

  1. Kurland LT, Molgaard CA. The patient record in epidemiology. Sci Am 1981;245:54 -63.
  2. Savage D, Corwin L, McGee D, Kannel W, Wolf P. Epidemiologic features of isolated syncope: the Framingham Study. Stroke 1985;16:626 -9.
  3. Kapoor W, Karpf M, Wieand S, Peterson J, Levey GA. Prospective evaluation and follow-up of patients with syncope. N Engl J Med 1983;309:197-204.
  4. Kapoor W. Evaluation and outcome of patients with syncope. Medicine 1990;69:160 -75.
  5. Pratt J, Fleisher G. Syncope in children and adolescents. Pediatr Emerg Care 1989;5:80 -2.
  6. Gordon T, Moodie D, Passalacqua M, et al. A retrospective analysis of the cost-effective workup of syncope in children. Cleve Clin J Med 1987;54:391-4.

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Authors
Driscoll, D. J., Jacobsen, S. J., Porter, C.-B. J., & Wollan, P. C.
Affiliations
Mayo Clinic (US)
Corresponding author
Driscoll, David J
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
1997-04
Volume
29
Issue
5
Pages
1039-1045
ISSN
0735-1097 (ISSN-L)
OpenAlex
W1968783736
Cited by
283
References
0
Citations by year
2026: 5 · 2025: 5 · 2024: 4 · 2023: 2 · 2022: 7 · 2021: 12 · 2020: 11 · 2019: 5 · 2018: 6 · 2017: 16 · 2016: 10 · 2015: 8 · 2014: 13 · 2013: 19 · 2012: 13
FWCI
8.96
Type
journal article
Language
en
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Mayo Foundation for Medical Education and Research
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR030582, AR30582)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Neurological and metabolic disorders
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Keywords
syncope, children, adolescents, incidence, long-term outcomes, sudden death, exertional syncope, electrocardiogram, Rochester Epidemiology Project, sex differences
MeSH terms
Adolescent, Child, Female, Humans, Male, Minnesota, Syncope, Incidence, Syncope, Vasovagal

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