Syncope in Children and Adolescents
Abstract
Most strategies for managing syncope in children reflect data from studies involving the adult population. In the future, there will be a great need for studies in children and adolescents suffering from recurrent syncope. To date, there has been no Food and Drug Administration-approved therapy for neurocardiogenic syncope (NCS), the most common cause of syncope in both adults and children. None of the clinical trials of pharmacotherapy in NCS has shown benefit over placebo. NCS should be considered a chronic condition, and the aim of the therapy should be to decrease recurrence of syncope rather than to completely eliminate it.
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Neurally mediated syncope accounts for 75% of pediatric syncope.
“Neurally mediated syncope accounts for 75% of pediatric syncope, followed by psychogenic or unexplained syncope in 8% to 15% of cases (623).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [623]
Psychogenic or unexplained syncope accounts for 8% to 15% of pediatric syncope.
“Neurally mediated syncope accounts for 75% of pediatric syncope, followed by psychogenic or unexplained syncope in 8% to 15% of cases (623).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [623]
Cites
The incidence of congenital heart disease.
Hoffman, J. I. E., & Kaplan, S. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01886-7 · Cited by 6,099 · see citing works
Developed in collaboration with, European Heart Rhythm Association (EHRA), Heart Failure Association (HFA), and Heart Rhythm Society (HRS), societies, E. B. T. F., European Society of Emergency Medicine (EuSEM), European Federation of Internal Medicine (EFIM), European Union Geriatric Medicine Society (EUGMS), American Geriatrics Society (AGS), European Neurological Society (ENS), et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp298 · Cited by 2,040 · see citing works
Risk Stratification in the Long-QT Syndrome
Priori, S. G., Schwartz, P. J., Napolitano, C., Bloise, R., Ronchetti, E., Grillo, M., Vicentini, A., Spazzolini, C., Nastoli, J., Bottelli, G., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022147 · Cited by 1,456 · see citing works
The Consensus Committee of the American Autonomic Society and the American Academy of Neurology (1996) · Neurology · doi:10.1212/wnl.46.5.1470 · Cited by 1,238 · see citing works
Effectiveness and Limitations of β-Blocker Therapy in Congenital Long-QT Syndrome
Moss, A. J., Zaręba, W., Hall, W. J., Schwartz, P. J., Crampton, R. S., Benhorin, J., Vincent, G. M., Locati, E. H., Priori, S. G., Napolitano, C., et al. (2000) · Circulation · doi:10.1161/01.cir.101.6.616 · Cited by 836 · see citing works
Prolongation of the QT Interval and the Sudden Infant Death Syndrome
Schwartz, P. J., Stramba‐Badiale, M., Segantini, A., Austoni, P., Bosi, G., Giorgetti, R., Grancini, F., Marni, E., Perticone, F., Rosti, D., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199806113382401 · Cited by 686 · see citing works
Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies
Vernino, S., Low, P. A., Fealey, R. D., Stewart, J. D., Farrugia, G., & Lennon, V. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009213431204 · Cited by 674 · see citing works
Guidelines on Management (diagnosis and treatment) of syncope ? update 2004
Brignole, M., Alboni, P., Benditt, D. G., Bergfeldt, L., Blanc, J., Thomsen, P. E. B., van Dijk, J. G., Fitzpatrick, A. P., Hohnloser, S. H., Janousek, J., et al. (2004) · EP Europace · doi:10.1016/j.eupc.2004.08.008 · Cited by 648 · see citing works
Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary.
Brignole, M., Alboni, P., Benditt, D. G., Bergfeldt, L., Blanc, J., Thomsen, P. E. B., van Dijk, J. G., Fitzpatrick, A. P., Hohnloser, S. H., Janoušek, J., et al. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.09.004 · Cited by 562 · see citing works
Idiopathic postural orthostatic tachycardia syndrome: An attenuated form of acute pandysautonomia?
Schondorf, R., & Low, P. A. (1993) · Neurology · doi:10.1212/wnl.43.1_part_1.132 · Cited by 548 · see citing works
Postural orthostatic tachycardia syndrome: the Mayo clinic experience
Thieben, M. J., Sandroni, P., Sletten, D. M., Benrud-Larson, L. M., Fealey, R. D., Vernino, S., Low, P. A., Lennon, V. A., & Shen, W.-K. (2007) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)61027-6 · Cited by 516 · see citing works
Brignole, M., Menozzi, C., Moya, A., Andresen, D., Blanc, J. J., Krahn, A. D., Wieling, W., Beiras, X., Deharo, J. C., Russo, V., et al. (2012) · Circulation · doi:10.1161/circulationaha.111.082313 · Cited by 437 · see citing works
Misdiagnosis of epilepsy: many seizure-like attacks have a cardiovascular cause
Zaidi, A., Clough, P., Cooper, P., Scheepers, B., & Fitzpatrick, A. P. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00700-2 · Cited by 422 · see citing works
Dysautonomia in the joint hypermobility syndrome
Gazit, Y., Nahir, A. M., Grahame, R., & Jacob, G. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(03)00235-3 · Cited by 390 · see citing works
Survival in Childhood Pulmonary Arterial Hypertension
Barst, R. J., McGoon, M. D., Elliott, C. G., Foreman, A. J., Miller, D. P., & Ivy, D. D. (2011) · Circulation · doi:10.1161/circulationaha.111.026591 · Cited by 380 · see citing works
Management of Vasovagal Syncope: Controlling or Aborting Faints by Leg Crossing and Muscle Tensing
Krediet, C. T. P., van Dijk, N., Linzer, M., van Lieshout, J. J., & Wieling, W. (2002) · Circulation · doi:10.1161/01.cir.0000030939.12646.8f · Cited by 372 · see citing works
Cardiac Atrophy After Bed-Rest Deconditioning: A Nonneural Mechanism for Orthostatic Intolerance
Levine, B. D., Zuckerman, J. H., & Pawelczyk, J. A. (1997) · Circulation · doi:10.1161/01.cir.96.2.517 · Cited by 371 · see citing works
Low, P. A., & Benarroch, E. E. (2009) · Cited by 345 · see citing works
Sequelae of Kawasaki disease in adolescents and young adults
Burns, J. C., Shike, H., Gordon, J. B., Malhotra, A., Schoenwetter, M., & Kawasaki, T. (1996) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(96)00099-x · Cited by 335 · see citing works
AHA/ACCF Scientific Statement on the Evaluation of Syncope
Strickberger, S. A., Benson, D. W., Biaggioni, I., Callans, D. J., Cohen, M. I., Ellenbogen, K. A., Epstein, A. E., Friedman, P. A., Goldberger, J. J., Heidenreich, P. A., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.170274 · Cited by 331 · see citing works
Kapoor, W. N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200012213432507 · Cited by 322 · see citing works
Postural Tachycardia Syndrome (POTS)
Raj, S. R. (2013) · Circulation · doi:10.1161/circulationaha.112.144501 · Cited by 320 · see citing works
Hypertrophic Obstructive Cardiomyopathy
Nishimura, R. A., & Holmes, D. R. (2004) · New England Journal of Medicine · doi:10.1056/nejmcp030779 · Cited by 319 · see citing works
Postural tachycardia syndrome (POTS)
Lamotte, G., & Low, P. A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85492-4.00118-6 · Cited by 300 · see citing works
Clinical Aspects and Prognosis of Brugada Syndrome in Children
Probst, V., Denjoy, I., Meregalli, P. G., Amirault, J.-C., Sacher, F., Mansourati, J., Babuty, D., Villain, E., Victor, J., Schott, J., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.664219 · Cited by 298 · see citing works
AUTONOMIC FAILURE: A TEXTBOOK OF CLINICAL DISORDERS OF THE AUTONOMIC NERVOUS SYSTEM.
van Dijk, D. J. G. (2000) · Brain · doi:10.1093/brain/123.9.1972 · Cited by 297 · see citing works
The epidemic of orthostatic tachycardia and orthostatic intolerance
Robertson, D. (1999) · The American Journal of the Medical Sciences · doi:10.1016/s0002-9629(15)40480-x · Cited by 293 · see citing works
BREATHHOLDING SPELLS (CYANOTIC AND PALLID INFANTILE SYNCOPE)
LOMBROSO, C. T., & Lerman, P. (1967) · PEDIATRICS · doi:10.1542/peds.39.4.563 · Cited by 291 · see citing works
Autonomic failure: A textbook of clinical disorders of the autonomic nervous system
Toole, J. F. (1993) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(93)90257-y · Cited by 289 · see citing works
Syncope in Children and Adolescents
Driscoll, D. J., Jacobsen, S. J., Porter, C.-B. J., & Wollan, P. C. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00020-x · Cited by 283 · see citing works
Orthostatic intolerance and chronic fatigue syndrome associated with Ehlers-Danlos syndrome
Rowe, P. C., Barron, D. F., Calkins, H., Maumenee, I. H., Tong, P. Y., & Geraghty, M. T. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70173-3 · Cited by 230 · see citing works
Self-citationPachon M, J. C., Pachon M, E. I., Cunha Pachon, M. Z., Lobo, T. J., Pachon M, J. C., & Santillana P, T. G. (2011) · Europace · doi:10.1093/europace/eur163 · Cited by 230 · see citing works
Sarkozy, A., Boussy, T., Kourgiannides, G., Chierchia, G., Richter, S., Potter, T. D., Geelen, P., Wellens, F., Spreeuwenberg, M. D., & Brugada, P. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehl450 · Cited by 230 · see citing works
(1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.10.1207 · Cited by 213 · see citing works
Grubb, B. P. (2005) · New England Journal of Medicine · doi:10.1056/nejmcp042601 · Cited by 208 · see citing works
Madrid, A. H., Ortega, J., Rebollo, J. G., Manzano, J. G., Segovia, J. G., Sánchez, A., Peña, G., & Moro, C. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01155-4 · Cited by 205 · see citing works
THE EFFECT OF POSTURE UPON THE COMPOSITION AND VOLUME OF THE BLOOD IN MAN 1
Thompson, W. O., Thompson, P. K., & Dailey, M. E. (1928) · Journal of Clinical Investigation · doi:10.1172/jci100179 · Cited by 203 · see citing works
Sy, R. W., Gollob, M. H., Klein, G. J., Yee, R. K., Skanes, A. C., Gula, L. J., Leong‐Sit, P., Gow, R. M., Green, M. S., BIRNIE, D. H., et al. (2011) · Heart Rhythm · doi:10.1016/j.hrthm.2011.01.048 · Cited by 203 · see citing works
Arrhythmias in a Contemporary Fontan Cohort
Stephenson, E. A., Lü, M., Berul, C. I., Etheridge, S. P., Idriss, S. F., Margossian, R. E., Reed, J. H. C., Prakash, A., Sleeper, L. A., Vetter, V. L., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.03.079 · Cited by 198 · see citing works
Guidelines on management (diagnosis and treatment) of syncope—update 2004
Brignole, M., Alboni, P., & Benditt, D. G. (2005) · ACC Current Journal Review · doi:10.1016/j.accreview.2005.02.024 · Cited by 189 · see citing works
Prospective Study of Children With Cyanotic and Pallid Breath-Holding Spells
DiMario, F. J. (2001) · PEDIATRICS · doi:10.1542/peds.107.2.265 · Cited by 174 · see citing works
Reflex anoxic seizures ('white breath-holding'): nonepileptic vagal attacks.
Stephenson, J. B. P. (1978) · Archives of Disease in Childhood · doi:10.1136/adc.53.3.193 · Cited by 156 · see citing works
Syncope in pediatric patients presenting to an emergency department
Massin, M. M., Bourguignont, A., Coremans, C., Comté, L., Lepage, P., & Gérard, P. (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.01.048 · Cited by 156 · see citing works
Yao, Y., Shi, R., Wong, T., Zheng, L., Chen, W., Yang, L., Huang, W., Bao, J., & Zhang, S. (2012) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.111.966465 · Cited by 155 · see citing works
SYNCOPE IN THE PEDIATRIC PATIENT
Lewis, D. A., & Dhala, A. (1999) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70113-9 · Cited by 143 · see citing works
Idiopathic Orthostatic Intolerance and Postural Tachycardia Syndromes
Jacob, G., & Biaggioni, I. (1999) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199902000-00003 · Cited by 136 · see citing works
Outcomes and Associated Risk Factors for Aortic Valve Replacement in 160 Children
Karamlou, T., Jang, K., Williams, W. G., Caldarone, C. A., Arsdell, G. V., Coles, J. G., & McCrindle, B. W. (2005) · Circulation · doi:10.1161/circulationaha.105.541649 · Cited by 127 · see citing works
Syncope: Mechanisms and Management
(2005) · Wiley eBooks · doi:10.1002/9780470994801 · Cited by 127 · see citing works
Scott, W. A., Pongiglione, G., Bromberg, B. I., Schaffer, M. S., Deal, B. J., Fish, F. A., & Dick, M. (1995) · The American Journal of Cardiology · doi:10.1016/s0002-9149(99)80110-6 · Cited by 120 · see citing works
Chronic orthostatic intolerance and the postural tachycardia syndrome (POTS)
Stewart, J. M. (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.06.084 · Cited by 116 · see citing works
Stewart, J. M., Gewitz, M. H., Weldon, A., & Munoz, J. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70025-9 · Cited by 110 · see citing works
The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope
Qingyou, Z., Junbao, D., & Chaoshu, T. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2006.07.031 · Cited by 108 · see citing works
Prevalence, incidence, and classification of epilepsy in the Faroes
Joensen, P. (1986) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1986.tb04642.x · Cited by 106 · see citing works
Exposure in vivo vs applied relaxation in the treatment of blood phobia
Öst, L., Lindahl, I.-L., Sterner, U., & Jerremalm, A. (1984) · Behaviour Research and Therapy · doi:10.1016/0005-7967(84)90001-9 · Cited by 100 · see citing works
(1990) · Mac Keith Press eBooks · Cited by 95 · see citing works
Maintenance of postural normotension in humans
Wieling, W., & LIESHOUT, J. J. V. (1997) · Cited by 89 · see citing works
Twenty-Five Year Experience With Balloon Aortic Valvuloplasty for Congenital Aortic Stenosis
Maskatia, S. A., Ing, F. F., Justino, H., Crystal, M. A., Mullins, C. E., Mattamal, R. J., Smith, E. O., & Petit, C. J. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.05.040 · Cited by 85 · see citing works
Anoxic-epileptic seizures: observational study of epileptic seizures induced by syncopes
Stephenson, J. B. P. (2005) · Archives of Disease in Childhood · doi:10.1136/adc.2005.075408 · Cited by 85 · see citing works
Selective association of fainting with blood-injury-illness fear
Connolly, J., Hallam, R., & Marks, I. M. (1976) · Behavior Therapy · doi:10.1016/s0005-7894(76)80214-6 · Cited by 84 · see citing works
Blood Volume Perturbations in the Postural Tachycardia Syndrome
Raj, S. R., & Robertson, D. (2007) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e318063c6c0 · Cited by 80 · see citing works
Orthostatic intolerance in pediatrics
Stewart, J. M. (2002) · The Journal of Pediatrics · doi:10.1067/mpd.2002.122727 · Cited by 77 · see citing works
Jordan, J., Shannon, J. R., Diedrich, A., Black, B. K., & Robertson, D. (2002) · Hypertension · doi:10.1161/hy1201.097202 · Cited by 69 · see citing works
Hypertrophic Cardiomyopathy in Childhood
Colan, S. D. (2010) · Heart Failure Clinics · doi:10.1016/j.hfc.2010.05.004 · Cited by 68 · see citing works
Syncope in children and adolescents
PRATT, J. L., & FLEISHER, G. R. (1989) · Pediatric Emergency Care · doi:10.1097/00006565-198906000-00002 · Cited by 68 · see citing works
The “Mess Trick” and the “Fainting Lark”
Howard, P. H., Leathart, G. L., Dornhorst, A. C., & Sharpey‐Schafer, E. P. (1951) · BMJ · doi:10.1136/bmj.2.4728.382 · Cited by 67 · see citing works
Kanjwal, K., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2010) · International Journal of Medical Sciences · doi:10.7150/ijms.7.62 · Cited by 66 · see citing works
Self-citationHypertrophic cardiomyopathy in childhood and adolescence – strategies to prevent sudden death
Östman‐Smith, I. (2010) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2010.00869.x · Cited by 64 · see citing works
Handbook of clinical neurology, vol. 15 (the epilepsies)
Foster, J. B. (1978) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(78)90170-3 · Cited by 64 · see citing works
Palmisano, P., Zaccaria, M., Luzzi, G., Nacci, F., Anaclerio, M., & Favale, S. (2012) · EP Europace · doi:10.1093/europace/eur419 · Cited by 63 · see citing works
Dong, J., Edelmann, L. J., Bajwa, A., Kornreich, R., & Desnick, R. J. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10450 · Cited by 63 · see citing works
Ventricular tachycardia in children
Rocchini, A. P., Chun, P. O., & Dick, M. (1981) · The American Journal of Cardiology · doi:10.1016/0002-9149(81)90218-6 · Cited by 60 · see citing works
Sudden cardiac death in the pediatric population.
Gillette, P. C., & Garson, A. (1992) · PubMed · Cited by 58 · see citing works
GUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF SYNCOPE (2009)
Moya‐Mitjans, À., Sutton, R., Ammirati, F., Blanc, J., Brignole, M., Dahm, J. B., Deharo, J., Gajek, J. J., Gjesdal, K., Krahn, A. D., et al. (2010) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2010-6-2-229-259 · Cited by 55 · see citing works
Cardiac Syncope in Pediatric Patients
MASSIN, M. M., Malekzadeh-Milani, S. G., & Benatar, A. A. (2007) · Clinical Cardiology · doi:10.1002/clc.28 · Cited by 50 · see citing works
Autonomic dysfunction presenting as postural tachycardia syndrome following traumatic brain injury.
Kanjwal, K., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2010) · PubMed · Cited by 48 · see citing works
Self-citationAre Implantable Loop Recorders Useful in Detecting Arrhythmias in Children with Unexplained Syncope?
Dhahri, K. N. A., Potts, J. E., Chiu, C., Hamilton, R. M., & Sanatani, S. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02486.x · Cited by 46 · see citing works
Postural orthostatic tachycardia syndrome following Lyme disease.
Kanjwal, K., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2011) · PubMed · Cited by 44 · see citing works
Self-citationGanglionated plexi ablation in right atrium to treat cardioinhibitory neurocardiogenic syncope
Rebecchi, M., de Ruvo, E., Strano, S., Sciarra, L., Golia, P., Martino, A., & Calò, L. (2012) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-012-9666-5 · Cited by 41 · see citing works
Kanjwal, K., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2009) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-009-9452-1 · Cited by 38 · see citing works
Self-citationStanding, orthostatic stress, and autonomic function
Wieling, W. (1988) · Cited by 36 · see citing works
Clinical features and investigation of the primary autonomic failure syndromes
Bannister, R. (1992) · Medical Entomology and Zoology · Cited by 35 · see citing works
Zhao, L., JIAYOU, Z., Wu, Z., & De-ning, L. (2012) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2011.03320.x · Cited by 32 · see citing works
The Long-QT Syndrome — Bedside to Bench to Bedside
Vincent, G. M. (2003) · New England Journal of Medicine · doi:10.1056/nejmp030039 · Cited by 30 · see citing works
Effective Utilization of Home-Video Recordings for the Evaluation of Paroxysmal Events in Pediatrics
Sheth, R. D., & Bodensteiner, J. B. (1994) · Clinical Pediatrics · doi:10.1177/000992289403301001 · Cited by 27 · see citing works
Haensch, C., Lerch, H., Schlemmer, H., Jigalin, A., & Isenmann, S. (2009) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.168484 · Cited by 26 · see citing works
Distinguishing Benign Syncope from Life-Threatening Cardiac Causes of Syncope
Strieper, M. J. (2005) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2005.01.001 · Cited by 26 · see citing works
Dysautonomic (Orthostatic) Syncope
Grubb, B. P. (2005) · doi:10.1002/9780470994801.ch3 · Cited by 25 · see citing works
Ventricular arrhythmias and sudden death in children
Garson, A., Smith, R. T., Moak, J. P., Ross, B. A., & McNamara, D. G. (1985) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(85)80542-8 · Cited by 25 · see citing works
Yılmaz, S., Gökben, S., Levent, E., Serdaroğlu, G., & Özyürek, R. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.02.006 · Cited by 23 · see citing works
Kanjwal, K., Karabin, B. L., Kanjwal, Y., Saeed, B., & Grubb, B. P. (2010) · Clinical Cardiology · doi:10.1002/clc.20805 · Cited by 21 · see citing works
Self-citationGUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF SYNCOPE (2009)
Moya, A., Sutton, R., Ammirati, F., Blanc, J.-J., Brignole, M., Dahm, J. B., Deharo, J.-C., Gajek, J., Gjesdal, K., Krahn, A., et al. (2010) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2010-6-1-108-116 · Cited by 21 · see citing works
Wieling, W., & LIESHOUT, J. J. V. (2002) · Clinical Autonomic Research · doi:10.1007/s10286-002-0019-9 · Cited by 20 · see citing works
Right ventricular cardiomyopathy in the young: An emerging challenge
Hamilton, R. M., & Fidler, L. M. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.01.026 · Cited by 19 · see citing works
Kanjwal, K., Karabin, B. L., Sheikh, M. A., Kanjwal, Y., & Grubb, B. P. (2010) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-010-9506-4 · Cited by 15 · see citing works
Self-citationPsychogenic Syncope? A Cautionary Note
Kanjwal, K., Kanjwal, Y., Karabin, B. L., & Grubb, B. P. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02400.x · Cited by 14 · see citing works
Self-citationSyncope in the Child and Adolescent
Grubb, B. P., & Friedman, R. A. (2005) · Wiley eBooks · doi:10.1002/9780470994801.ch16 · Cited by 13 · see citing works
Paced breathing can prevent vasovagal syncope during head-up tilt testing.
Jáuregui‐Renaud, K., Márquez, M. F., Hermosillo, A. G., Sobrino, A., Lara, J. L., Kostine, A., & Cárdenas, M. (2003) · PubMed · Cited by 13 · see citing works
Arrhythmias in Pediatric Patients
Garson, A. (1984) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)31091-4 · Cited by 12 · see citing works
Rowe, P. C., Barron, D. F., Calkins, H. G., Maumenee, I. H., Tong, P. Y., & Geraghty, M. T. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70176-9 · Cited by 10 · see citing works
Self-citationRossi, L. N. (1989) · Child s Nervous System · doi:10.1007/bf00272112 · Cited by 10 · see citing works
Head‐up tilt testing in children and young people: A retrospective observational study
Dietz, S. M., Murfitt, J., Florence, L., Thakker, P., & Whitehouse, W. P. (2011) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2010.01951.x · Cited by 7 · see citing works
Postural Orthostatic Tachycardia Syndrome: A Rare Complication Following Electrical Injury
Kanjwal, K., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02634.x · Cited by 7 · see citing works
Self-citationÇeli̇k, M., Sarıtaş, B., Tatar, T., Özkan, M., Akay, T., & Aşlamacı, S. (2012) · The Anatolian Journal of Cardiology · doi:10.5152/akd.2012.099 · Cited by 6 · see citing works
[Pulmonary arterial hypertension in childhood].
Douwes, J. M., van Loon, R. L. E., Roothooft, M. T. R., & Berger, R. M. F. (2011) · PubMed · Cited by 4 · see citing works
Nadel im Heuhaufen - potentiell gefährliche Synkopen bei Kindern
Pfammatter (2011) · Praxis · doi:10.1024/1661-8157/a000734 · Cited by 2 · see citing works
[Application of the head-up tilt table test in children under 6 years old].
Lin, P., Wang, C., Cao, M.-J., Luo, H., Xu, Y., & Xie, Z. (2012) · PubMed · Cited by 2 · see citing works
Clinical features and evaluation of the primary autonomic failure syndromes
Bannister, R., Iodice, V., Vichayanrat, E., & Mathias, C. J. (2013) · Oxford University Press eBooks · doi:10.1093/med/9780198566342.003.0041 · Cited by 2 · see citing works
Flagged first, then by citations
5 of the 112 references couldn’t be matched to a known paper.
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2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.004 · Cited by 484 · see citing works
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000499 · Cited by 453 · see citing works
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000498 · Cited by 408 · see citing works
2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.003 · Cited by 327 · see citing works
Prospective Evaluation of Autonomic Dysfunction in Post-Acute Sequela of COVID-19
Jamal, S. M., Landers, D. B., Hollenberg, S. M., Turi, Z. G., Glotzer, T. V., Tancredi, J., & Parrillo, J. E. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.03.357 · Cited by 100 · see citing works
Coupal, K. E., Heeney, N. D., Hockin, B. C. D., Ronsley, R. J., Armstrong, K. R., Sanatani, S., & Claydon, V. E. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01197 · Cited by 42 · see citing works
SINGHI, P. D., & Saini, A. G. (2017) · The Indian Journal of Pediatrics · doi:10.1007/s12098-017-2488-9 · Cited by 21 · see citing works
Cui, Y., Zhang, J., Wang, Y., Liao, Y., Liu, K., Xu, W., WU, S. M., Sun, C., Zhang, C., Zhang, Q., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105595 · Cited by 13 · see citing works
Schunk, P. C., & Ruttan, T. (2018) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2017.12.005 · Cited by 14 · see citing works
Screening Pediatric Patients in New-Onset Syncope (SPINS) Study
Gupta, A., Menoch, M., Levasseur, K. A., & Gonzalez, I. E. (2019) · Clinical Pediatrics · doi:10.1177/0009922819885660 · Cited by 12 · see citing works
Cui, Y., Liao, Y., Zhang, Q., Yan, H., Liu, P., Wang, Y., Sun, Y. K., Xu, W., Liu, X., Du, J., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1017505 · Cited by 12 · see citing works
Zhu, W., Bian, X., & Lv, J. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1481749 · Cited by 8 · see citing works
Role of implantable loop recorders in patients with postural orthostatic tachycardia syndrome
Kanjwal, K., Qadir, R., Ruzieh, M., & Grubb, B. P. (2018) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.13441 · Cited by 8 · see citing works
Self-citationSynkopen bei Kindern und Jugendlichen
Müller, M. J., & Paul, T. (2018) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-018-0562-2 · Cited by 7 · see citing works
Yuan, P., Li, X., Tao, C., Du, X., Zhang, C., Du, J., Huang, Y., & Liao, Y. (2022) · International Journal of General Medicine · doi:10.2147/ijgm.s352928 · Cited by 7 · see citing works
Congenital Anomalous Origin of Coronary Artery Disease in Children With Syncope: A Case Series
Gao, Y., Zhang, Q., Sun, Y. K., & Du, J. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.879753 · Cited by 7 · see citing works
Kolarczyk, E. B., Szydłowski, L., Skierska, A., & Markiewicz‐Łoskot, G. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17124524 · Cited by 6 · see citing works
The Repolarization Period during the Head-Up Tilt Test in Children with Vasovagal Syncope
Kolarczyk, E. B., Markiewicz‐Łoskot, G., & Szydłowski, L. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17061908 · Cited by 6 · see citing works
Epidemiology of the syncope in children and adolescents in elite sport (EPISODE-S research)
Makarov, L. M., Komolyatova, V. N., Kiseleva, I. I., Aksenova, N. V., Беспорточный, Д. А., Балыкова, Л. А., & Паршина, Т. С. (2020) · Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) · doi:10.21508/1027-4065-2019-64-6-62-67 · Cited by 6 · see citing works
Dangerous noodle: A case of swallowing syncope and a review of 122 cases from the literature
Uraguchi, K., Kariya, S., Makihara, S., Oka, A., Ueeda, H., Noda, Y., & Nishizaki, K. (2018) · Journal of Arrhythmia · doi:10.1002/joa3.12130 · Cited by 5 · see citing works
Non-epileptic Paroxysmal Events
Armstrong‐Javors, A. (2022) · Springer eBooks · doi:10.1007/978-3-319-08290-5_8 · Cited by 4 · see citing works
Alnoor, M. S., Varner, H. K., Butler, I. J., Lankford, J. E., Zhu, L., & Numan, M. T. (2022) · Pediatric Cardiology · doi:10.1007/s00246-022-02815-1 · Cited by 4 · see citing works
Gumus, Y., & Senturk, E. (2022) · Cardiology in the Young · doi:10.1017/s1047951122001949 · Cited by 4 · see citing works
Oliveira, P. M. L., da Silva, R. M. F. L., Tonelli, H. D. A. F., Meira, Z. M. A., & Mota, C. D. C. C. (2023) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20220543 · Cited by 4 · see citing works
Micturition Syncope in Childhood
Marzuillo, P., Guarino, S., Tipo, V., Apicella, A., Grandone, A., Diplomatico, M., Polito, C., del Giudice, E. M., Manna, A. L., & Perrone, L. (2017) · Pediatric Emergency Care · doi:10.1097/pec.0000000000001345 · Cited by 4 · see citing works
Common Childhood Epilepsy Mimics
Samia, P., & Wilmshurst, J. M. (2020) · Springer eBooks · doi:10.1007/978-3-319-43153-6_23 · Cited by 4 · see citing works
The prevalence of loss of consciousness in children of school age
Makarov, L. M., Lesnitskaya, M. G., Комолятова, В. Н., & Kiseleva, I. I. (2020) · Health Care of the Russian Federation · doi:10.46563/0044-197x-2020-64-4-190-195 · Cited by 2 · see citing works
Park, E. G., Eom, T., Han, J. Y., Bin, J. H., Oh, J.-H., Kim, Y., & Yoo, I. H. (2024) · Translational Pediatrics · doi:10.21037/tp-24-252 · Cited by 2 · see citing works
Retrospective Evaluation of Patients Admitted With Complaints of Syncope
CEYLAN, N., Aydoğmuş, Ü., Karalök, Z. S., Taşkın, B. D., & Cahide, Y. (2016) · Cited by 2 · see citing works
Gonzalez-Garcia, J., Fernandez-Alvarez, R., Angelats-Romero, C. M., Ballestero, Y., Martinez, J., & Mintegi, S. (2019) · Pediatric Emergency Care · doi:10.1097/pec.0000000000001864 · Cited by 2 · see citing works
Neurally Mediated Syncope in Children and Adolescents: An Updated Narrative Review
da Silva, R. M. F. L., Oliveira, P. M. L., Tonelli, H. A. F., Meira, Z. M. A., & Mota, C. D. C. C. (2022) · The Open Cardiovascular Medicine Journal · doi:10.2174/18741924-v16-e2205110 · Cited by 2 · see citing works
Lukich, S., Sarin, A., Pierce, J., Russell, M. W. W., & Malas, N. (2023) · Journal of the Academy of Consultation-Liaison Psychiatry · doi:10.1016/j.jaclp.2023.03.006 · Cited by 2 · see citing works
Fatal Coronary Artery Anomaly Concealed in Young Athletes with Exertional Syncope
Ifuku, T., Nakatani, K., Ueno, K., Yamashita, N., & Imoto, Y. (2024) · Case Reports in Pediatrics · doi:10.1155/2024/6390066 · Cited by 2 · see citing works
2018 KHRS guideline for the evaluation and management of syncope-Part 1
Park, J., Cha, M.-J., Kim, D. H., Kim, Y. R., Mun, H. S., Bae, E. J., Seo, D. W., Song, M. K., Ahn, J., Yoon, H. D., et al. (2018) · International Journal of Arrhythmia · doi:10.18501/arrhythmia.2018.009 · Cited by 1 · see citing works
Micturition syncope with asystole in a paediatric patient
Trivedi, M. K., & Arora, G. (2020) · Cardiology in the Young · doi:10.1017/s1047951120004473 · Cited by 1 · see citing works
2018 KHRS guideline for the evaluation and management of syncope-Part 2
Kim, Y. R., Chun, K. J., Kim, J. S., Mun, H. S., Park, J., Seo, D. W., Song, M. K., Ahn, J. H., Yoon, H. J., Lee, D. I., et al. (2018) · International Journal of Arrhythmia · doi:10.18501/arrhythmia.2018.010 · Cited by 1 · see citing works
Zhang, M., Cao, X., & Zhang, Y. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-02693-z · Cited by 1 · see citing works
Lee, D. W. (2025) · Korean Journal of Pediatrics · doi:10.3345/cep.2025.00927 · Cited by 1 · see citing works
Síncope em idade pediátrica: avaliação e estratificação de risco
Álvares, S. (2016) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.25753/birth&growthmj.v24.i2.8558
A case report of cardiogenic syncope in the adolescent.
Gayduk, O. I., Иванусь, С. Г., Gayduk, T. A., Shvirid, I. I., Крамаренко, Л. Н., & Baralej, T. V. (2018) · Medicni perspektivi · doi:10.26641/2307-0404.2018.1(part2).126937
Aproximación clínica al paciente con trastorno de conciencia episódico
Palomo, M. J. S., del Barrio, M. T. A., & Izquierdo, A. Y. (2019) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/j.med.2019.02.002
Differenzialdiagnose der Synkope
Hahn, A., & Khalil, M. (2021) · Pädiatrie up2date · doi:10.1055/a-1193-9060
Outcomes of Inpatient Child Neurology Consultations
Ekici, A., Havalı, C., BALDAN, E., Bostancı, M., & KILIÇ, N. (2021) · OSMANGAZİ JOURNAL OF MEDICINE · doi:10.20515/otd.1017060
Philouze, P., Montoy, M., & Céruse, P. (2022) · European Annals of Otorhinolaryngology Head and Neck Diseases · doi:10.1016/j.anorl.2022.01.003
The Differential Diagnosis of Epilepsy
Zuberi, S. M., & Symonds, J. D. (2016) · Springer eBooks · doi:10.1007/978-3-319-39144-1_5
Recurrent syncope in a 16‐year‐old boy
Gunn, S., Dragulescu, A., Livingston, J., Avila, L., Abohweyere, J., Almadani, M., & Kukreti, V. (2022) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.16249
Cohen, G. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-76174-1.00007-9
Philouze, P., Montoy, M., & Céruse, P. (2022) · Annales françaises d Oto-rhino-laryngologie et de Pathologie Cervico-faciale · doi:10.1016/j.aforl.2021.12.008
Rivera, D. M. T., Gayanilo, M. A., & Swati, S. (2022) · Springer eBooks · doi:10.1007/978-3-031-10494-7_12
Synkope im Kindes- und Jugendalter aus kardiologischer Sicht
Bahlmann, J. (2024) · Kinder- und Jugendmedizin · doi:10.1055/a-2205-3528
Peličić, M., Petrić, M., Pešterac, A., & Tadić, B. V. (2024) · Medicinski podmladak · doi:10.5937/mp75-49877
Ramaswamy, P. (2025) · American Academy of PediatricsItasca, IL eBooks · doi:10.1542/9781610028219-79
- Authors
- Kanjwal, K., & Calkins, H.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Calkins, Hugh
- Venue
- Cardiology Clinics
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 33
- Issue
- 3
- Pages
- 397-409
- ISSN
- 0733-8651 (ISSN-L)
- OpenAlex
- W2179226474
- Cited by
- 52
- References
- 112
- Citations by year
- 2025: 4 · 2024: 5 · 2023: 2 · 2022: 13 · 2021: 2 · 2020: 6 · 2019: 4 · 2018: 7 · 2017: 6 · 2016: 3
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cardiology Clinics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
- Keywords
- syncope, recurrent syncope, vasovagal syncope, children, adolescents, pharmacotherapy, syncope management, syncope recurrence
- MeSH terms
- Adolescent, Child, Humans, Recurrence, Incidence, Tilt-Table Test, Syncope, Vasovagal, Disease Management
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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