Cited by 136Cancer survivorship and carePain Management and Opioid UseCancer-related cognitive impairment studies

Validation of the German Version of the Brief Fatigue Inventory

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Radbruch, Lukas, Sabatowski, Rainer, Elsner, Frank, Everts, Jan, Mendoza, Tito, Cleeland, Charles·2003·Journal of Pain and Symptom Management

Abstract

Sedation and tiredness are among the most frequent symptoms among cancer patients. A detailed assessment of these symptoms is necessary to evaluate therapeutic effects, such as the use of methylphenidate or comparison of different opioids. The Brief Fatigue Inventory (BFI) has been validated as a short and comprehensive instrument to assess severity of fatigue and fatigue-related impairment in cancer patients. We validated the German version of the BFI in patients with chronic cancer-related and noncancer-related pain treated in a tertiary pain center. Patients treated in the Pain Clinic of the Department of Anesthesiology completed the BFI, the minimal documentation system (MIDOS) and the short form SF-36 quality-of-life questionnaire (SF-36). Test-retest reliability was assessed with a second BFI immediately after the consultation and in a subgroup of patients after 3 to 7 days. Nineteen percent of the 117 patients were treated for cancer-related pain (C); the other patients suffered from chronic severe pain of nonmalignant origin (NC). Patients reported mean values for average fatigue of 3.9 (C) and 4.9 (NC), and for worst fatigue of 5.5 (C) and 6.2 (NC). The mean score of the 6 impairment items was 4.3 in both groups. Factor analysis led to a solution with one common factor for all nine items. Fatigue on the BFI correlated highly with 'feeling tired' in the SF-36 and with 'sedation' in MIDOS, and less with 'being worn out' in SF-36 and 'weakness' in MIDOS. Internal consistency was high, as was test-retest reliability, with a correlation of the intensity, mean scores of 0.93 and the impairment mean scores of 0.87. In conclusion, we found the German version of the BFI to be reliable and valid for cancer and noncancer patients. Minor differences were seen in the validation compared to the original version.

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Crossref · 10.1016/s0885-3924(03)00073-3

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Authors
Radbruch, L., Sabatowski, R., Elsner, F., Everts, J., Mendoza, T., & Cleeland, C.
Affiliations
  • RWTH Aachen University (DE)
  • University of Cologne (DE)
  • The University of Texas MD Anderson Cancer Center (US)
Corresponding author
Radbruch, Lukas
Venue
Journal of Pain and Symptom Management
Publisher
Elsevier BV
Published
2003-05
Volume
25
Issue
5
Pages
449-458
ISSN
0885-3924 (ISSN-L)
OpenAlex
W1971709946
Cited by
136
References
28
Citations by year
2026: 5 · 2025: 4 · 2024: 6 · 2023: 13 · 2022: 7 · 2021: 6 · 2020: 10 · 2019: 6 · 2018: 6 · 2017: 10 · 2016: 5 · 2015: 6 · 2014: 9 · 2013: 3 · 2012: 6
FWCI
1.50
Type
journal article
Language
en
Open access
Locations
  • Journal of Pain and Symptom Management (publishedVersion)
  • PubMed (publishedVersion)
  • RWTH Publications (RWTH Aachen) (submittedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
Keywords
Brief Fatigue Inventory, German version, fatigue analysis, cancer-related fatigue, chronic nonmalignant pain, sedation, test-retest reliability, internal consistency, SF-36, psychometric validation
MeSH terms
Adult, Aged, Aged, 80 and over, Fatigue, Female, Germany, Humans, Male, Middle Aged, Neoplasms, Pain, Pain Measurement, Severity of Illness Index, Time Factors, Reproducibility of Results

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